Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yi-Rong Peng"'
Publikováno v:
eLife, Vol 11 (2022)
The genesis of broad neuronal classes from multipotential neural progenitor cells has been extensively studied, but less is known about the diversification of a single neuronal class into multiple types. We used single-cell RNA-seq to study how newly
Externí odkaz:
https://doaj.org/article/a10efda4c53b4e888c1b7ce1e26c7c78
Autor:
Lin Zhang, Cavallini, Martina, Junqiang Wang, Ruiqi Xin, Qiangge Zhang, Guoping Feng, Sanes, Joshua R., Yi-Rong Peng
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/16/2024, Vol. 121 Issue 16, p1-12, 63p
Autor:
Andreas Liu, Elliott S. Milner, Yi-Rong Peng, Hannah A. Blume, Michael C. Brown, Gregory S. Bryman, Alan J. Emanuel, Philippe Morquette, Nguyen-Minh Viet, Joshua R. Sanes, Paul D. Gamlin, Michael Tri H. Do
Publikováno v:
Science. 379:376-381
Light regulates physiology, mood, and behavior through signals sent to the brain by intrinsically photosensitive retinal ganglion cells (ipRGCs). How primate ipRGCs sense light is unclear, as they are rare and challenging to target for electrophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bbe7679b2f47c086c065048ac3397b3
https://doi.org/10.1126/science.ade2024
https://doi.org/10.1126/science.ade2024
Autor:
Joshua Hahn, Aboozar Monavarfeshani, Mu Qiao, Allison Kao, Yvonne Kölsch, Ayush Kumar, Vincent P Kunze, Ashley M. Rasys, Rose Richardson, Herwig Baier, Robert J. Lucas, Wei Li, Markus Meister, Joshua T. Trachtenberg, Wenjun Yan, Yi-Rong Peng, Joshua R. Sanes, Karthik Shekhar
The basic plan of the retina is conserved across vertebrates, yet species differ profoundly in their visual needs (Baden et al., 2020). One might expect that retinal cell types evolved to accommodate these varied needs, but this has not been systemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e292aa86660bfaac7497790821a1b790
https://doi.org/10.1101/2023.04.07.536039
https://doi.org/10.1101/2023.04.07.536039
Autor:
Dejan Juric, Yi-Rong Peng, Joshua R. Sanes, Alexi McAdams, Aviv Regev, Wenjun Yan, Karthik Shekhar, Tavé van Zyl
Publikováno v:
Proc Natl Acad Sci U S A
Increased intraocular pressure (IOP) represents a major risk factor for glaucoma, a prevalent eye disease characterized by death of retinal ganglion cells; lowering IOP is the only proven treatment strategy to delay disease progression. The main dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f893056d2fbebbe973cf602e9274f34
https://doi.org/10.1073/pnas.2001250117
https://doi.org/10.1073/pnas.2001250117
The genesis of broad neuronal classes from multipotential neural progenitor cells has been extensively studied, but less is known about the diversification of a single neuronal class into multiple types. We used single-cell RNA-seq to study how newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fee32296a330fc9be9d108b2fbbd083
https://doi.org/10.1101/2021.10.21.465277
https://doi.org/10.1101/2021.10.21.465277
Autor:
Alapakkam P. Sampath, Yi-Rong Peng
Publikováno v:
Neuron
LRRTM4 is a trans-synaptic adhesion protein regulating glutamatergic synapse assembly on dendrites of central neurons. In the mouse retina, we find that LRRTM4 is enriched at GABAergic synapses on axon terminals of rod bipolar cells (RBCs). Knockout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c046e191d2aaa335b24671d6e2acb8d
https://doi.org/10.1016/j.neuron.2020.02.027
https://doi.org/10.1016/j.neuron.2020.02.027
Autor:
Yi-Rong Peng, Karthik Shekhar, Dejan Juric, Joshua R. Sanes, Wenjun Yan, Tavé van Zyl, Aviv Regev
Publikováno v:
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Most irreversible blindness results from retinal disease. To advance our understanding of the etiology of blinding diseases, we used single-cell RNA-sequencing (scRNA-seq) to analyze the transcriptomes of ∼85,000 cells from the fovea and peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163ddbb446c84798c6eb972866d2f718
https://doi.org/10.1038/s41598-020-66092-9
https://doi.org/10.1038/s41598-020-66092-9
Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina
Autor:
Joshua R. Sanes, Dustin Herrmann, Yi-Rong Peng, Anna Sappington, Michael Tri H. Do, Karthik Shekhar, Gregory S. Bryman, Aviv Regev, Tavé van Zyl, Wenjun Yan
Publikováno v:
PMC
High-acuity vision in primates, including humans, is mediated by a small central retinal region called the fovea. As more accessible organisms lack a fovea, its specialized function and its dysfunction in ocular diseases remain poorly understood. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f1e7ddb4f95309bb1f3a40afdadba9
https://hdl.handle.net/1721.1/125240
https://hdl.handle.net/1721.1/125240