Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yi-Qun Zhan"'
Autor:
Wen Zhang, Kai Liu, Guang-Ming Ren, Yu Wang, Ting Wang, Xian Liu, Dong-Xu Li, Yang Xiao, Xu Chen, Ya-Ting Li, Yi-Qun Zhan, Shen-Si Xiang, Hui Chen, Hui-Ying Gao, Ke Zhao, Miao Yu, Chang-Hui Ge, Chang-Yan Li, Zhi-Qiang Ge, Xiao-Ming Yang, Rong-Hua Yin
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-15 (2023)
Abstract BRISC (BRCC3 isopeptidase complex) is a deubiquitinating enzyme that has been linked with inflammatory processes, but its role in liver diseases and the underlying mechanism are unknown. Here, we investigated the pathophysiological role of B
Externí odkaz:
https://doaj.org/article/976a22490ada4e1e947f031064c6b5e8
Autor:
Wen Zhang, Lei Wang, Xue-Hua Sun, Xian Liu, Yang Xiao, Jie Zhang, Ting Wang, Hui Chen, Yi-Qun Zhan, Miao Yu, Chang-Hui Ge, Chang-Yan Li, Guang-Ming Ren, Rong-Hua Yin, Xiao-Ming Yang
Publikováno v:
Military Medical Research, Vol 8, Iss 1, Pp 1-12 (2021)
Abstract Background Toll-like receptor 5 (TLR5)-mediated pathways play critical roles in regulating the hepatic immune response and show hepatoprotective effects in mouse models of hepatic diseases. However, the role of TLR5 in experimental models of
Externí odkaz:
https://doaj.org/article/ba965b6bc0da4b2cbd7f794c213543cb
Autor:
Ke Zhao, Jin‐Fang Liu, Ya‐Xin Zhu, Xiao‐Ming Dong, Rong‐Hua Yin, Xian Liu, Hui‐Ying Gao, Feng‐Jun Xiao, Rui Gao, Qi Wang, Yi‐Qun Zhan, Miao Yu, Hui Chen, Hong‐Mei Ning, Cai‐Bo Zhang, Xiao‐Ming Yang, Chang‐Yan Li
Publikováno v:
Advanced Science, Vol 9, Iss 5, Pp n/a-n/a (2022)
Abstract Hematopoietic stem and progenitor cells (HSPCs) possess the remarkable ability to regenerate the whole blood system in response to ablated stress demands. Delineating the mechanisms that maintain HSPCs during regenerative stresses is increas
Externí odkaz:
https://doaj.org/article/1fd99d2df6e14542b000dd3d7bfac1d0
Autor:
Teng Luo, Fei-Xiang Zhang, Ke Zhao, Hui-Ying Gao, Shou-Guo Zhang, Lin Wang, Gui-Fang Dou, Ting Liu, Miao Yu, Yi-Qun Zhan, Hui Chen, Xiao-Ming Yang, Chang-Yan Li
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The compound [3-(1H-benzimidazol-2-methylene)-5-(2-methylphenylaminosulfo)-2-indolone], known as Indo5, is a novel selective inhibitor of c-Met and Trks, and it is a promising anticancer candidate against hepatocellular carcinoma (HCC). Assessing the
Externí odkaz:
https://doaj.org/article/378e2e5e4cf0476aa9a076f4272e65c4
Autor:
Teng Luo, Shou-Guo Zhang, Ling-Fei Zhu, Fei-Xiang Zhang, Wei Li, Ke Zhao, Xiao-Xue Wen, Miao Yu, Yi-Qun Zhan, Hui Chen, Chang-Hui Ge, Hui-Ying Gao, Lin Wang, Xiao-Ming Yang, Chang-Yan Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Human hepatocellular carcinoma (HCC) lacks effective curative therapy and there is an urgent need to develop a novel molecular-targeted therapy for HCC. Selective tyrosine kinase inhibitors have shown promise in treating cancers i
Externí odkaz:
https://doaj.org/article/0cef8bb1993441e5b04c9941734793d5
Autor:
Ke Zhao, Wei-Wei Zheng, Xiao-Ming Dong, Rong-Hua Yin, Rui Gao, Xiu Li, Jin-Fang Liu, Yi-Qun Zhan, Miao Yu, Hui Chen, Chang-Hui Ge, Hong-Mei Ning, Xiao-Ming Yang, Chang-Yan Li
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190794 (2018)
EDAG is multifunctional transcriptional regulator primarily expressed in the linloc-kit+Sca-1+ hematopoietic stem cells (HSC) and CD34+ progenitor cells. Previous studies indicate that EDAG is required for maintaining hematopoietic lineage commitment
Externí odkaz:
https://doaj.org/article/2248367e296840d6a36c3abb3f78ce9e
Autor:
Yu-E Hao, Dong-Fang He, Rong-Hua Yin, Hui Chen, Jian Wang, Shao-Xia Wang, Yi-Qun Zhan, Chang-Hui Ge, Chang-Yan Li, Miao Yu, Xiao-Ming Yang
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 688-704 (2015)
G protein‐coupled receptor kinase interactor 2 (GIT2) is a signaling scaffold protein involved in regulation of cytoskeletal dynamics and the internalization of G protein‐coupled receptors (GPCRs). The short‐splice form of GIT2 is expressed in
Externí odkaz:
https://doaj.org/article/6668a2d10b3f474e8560c7d2bf9786b6
Autor:
Xiang-Zhen Kong, Rong-Hua Yin, Hong-Mei Ning, Wei-Wei Zheng, Xiao-Ming Dong, Yang Yang, Fei-Fei Xu, Jian-Jie Li, Yi-Qun Zhan, Miao Yu, Chang-Hui Ge, Jian-Hong Zhang, Hui Chen, Chang-Yan Li, Xiao-Ming Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91557 (2014)
Hematopoiesis is a complex process regulated by sets of transcription factors in a stage-specific and context-dependent manner. THAP11 is a transcription factor involved in cell growth, ES cell pluripotency, and embryogenesis. Here we showed that THA
Externí odkaz:
https://doaj.org/article/7089654e462a4d59bed8e880ff8f2dd1
Autor:
Rui Huang, Long Zhao, Hui Chen, Rong-Hua Yin, Chang-Yan Li, Yi-Qun Zhan, Jian-Hong Zhang, Chang-hui Ge, Miao Yu, Xiao-Ming Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96246 (2014)
Mitochondria are involved in the regulation of cell differentiation processes, but its function changes and molecular mechanisms are not yet clear. In this study, we found that mitochondrial functions changed obviously when K562 cells were induced to
Externí odkaz:
https://doaj.org/article/da196f3df5944096a9a79c7ad718b694
Autor:
Yi-Qun Zhan, Yuan Wang, Miao Yu, Rong-Hua Yin, Xiao-Ming Yang, Pan Song, Chang-Yan Li, Chang-Hui Ge, Jian Hong, Xuelian Yao
Publikováno v:
Biochemistry and Cell Biology. 99:223-230
Abraxas brother protein 1 (ABRO1) is a subunit of the deubiquitinating enzyme BRCC36-containing isopeptidase complex and plays important roles in cellular responses to stress by interacting with its binding partners, such as ubiquitin-specific peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f733274023f5f5e3da11467ac5b0f42
https://doi.org/10.1139/bcb-2019-0279
https://doi.org/10.1139/bcb-2019-0279