Výsledky vyhledávání - "Yi-Quan Jiang"

Akademický článek

A Prospective, Single-Arm, Phase 2 Study of Modified Transarterial Chemoembolization Using Low-Dose Chemotherapy with Blank Microspheres Plus Low-Dose Lenvatinib and Microwave Ablation in Patients with Large (≥7 cm) Unresectable Hepatocellular Carcinoma: The TALEM Trial

Autor: Zhi-Mei Huang, Xue Han, Jian Wang, Ling Gu, Lu Tang, Shao-Yong Wu, Tian Di, Ying-Wen Hou, Wan Yee Lau, Yi-Quan Jiang, Jin-Hua Huang

Publikováno v: Liver Cancer, Pp 1-13 (2024)

Introduction: For patients with large unresectable hepatocellular carcinoma (HCC), the effectiveness of conventional transarterial chemoembolization (cTACE) remains suboptimal. This study investigated the efficacy and safety of modified TACE using lo

Externí odkaz: https://doaj.org/article/c8867ce335db4e1c8405b9245905b46a

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Akademický článek

Investigating Mechanisms of Response or Resistance to Immune Checkpoint Inhibitors by Analyzing Cell-Cell Communications in Tumors Before and After Programmed Cell Death-1 (PD-1) Targeted Therapy: An Integrative Analysis Using Single-cell RNA and Bulk-RNA Sequencing Data

Autor: Yi-Quan Jiang, Zi-Xian Wang, Ming Zhong, Lu-Jun Shen, Xue Han, Xuxiazi Zou, Xin-Yi Liu, Yi-Nan Deng, Yang Yang, Gui-Hua Chen, Wuguo Deng, Jin-Hua Huang

Publikováno v: OncoImmunology, Vol 10, Iss 1 (2021)

Currently, a significant proportion of cancer patients do not benefit from programmed cell death-1 (PD-1)-targeted therapy. Overcoming drug resistance remains a challenge. In this study, single-cell RNA sequencing and bulk RNA sequencing data from sa

Externí odkaz: https://doaj.org/article/69931149762342a5b49c13e2823b4304

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Akademický článek

Efficacy of Hepatic Resection vs. Radiofrequency Ablation for Patients With Very-Early-Stage or Early-Stage Hepatocellular Carcinoma: A Population-Based Study With Stratification by Age and Tumor Size

Autor: Yi-Quan Jiang, Zi-Xian Wang, Yi-Nan Deng, Yang Yang, Guo-Ying Wang, Gui-Hua Chen

Publikováno v: Frontiers in Oncology, Vol 9 (2019)

Background: Because of the poor health conditions of elderly patients (age >65) with very-early-stage and early-stage hepatocellular carcinoma (HCC), primary treatment via hepatic resection (HR), or radiofrequency ablation (RFA) must be considered. H

Externí odkaz: https://doaj.org/article/bb0aa1db64ef4253a0f7eb80b3b0d5fb

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Preoperative identification of microvascular invasion in hepatocellular carcinoma by XGBoost and deep learning

Autor: Yinan Deng, Guoying Wang, Kaining Zeng, Na Cheng, Xi-Jing Yan, Yi-Quan Jiang, Wei-Min Tang, Jian-ning Chen, Wen-Jing Huan, Wen-Qi Shi, Gui-hua Chen, Yang Yang, Kai Ma, Yefeng Zheng, Shilei Cao, Yang Haozhen, Chun-Kui Shao, Su-E Cao, Jin Wang

Publikováno v: Journal of Cancer Research and Clinical Oncology

Purpose Microvascular invasion (MVI) is a valuable predictor of survival in hepatocellular carcinoma (HCC) patients. This study developed predictive models using eXtreme Gradient Boosting (XGBoost) and deep learning based on CT images to predict MVI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49ffd700f7e57f8818b7cd8bb9ad547
https://doi.org/10.1007/s00432-020-03366-9

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LncRNA RP11-307C12.11 promotes the growth of hepatocellular carcinoma by acting as a molecular sponge of miR-138

Autor: Yi-Quan Jiang, Yiming Huang, Haibo Li, Tong Zhang, Kaining Zeng, Yusheng Cheng, Tingting Xia, Yang Yang, Yinan Deng

Publikováno v: Liver Research, Vol 3, Iss 3, Pp 240-249 (2019)

Background: Abnormal expression of long non-coding RNAs (lncRNAs) has been found in almost all tumors in humans, providing numerous potential diagnostic and prognostic biomarkers, and therapeutic targets. Materials and methods: The Cancer Genome Atla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6a239e4175284ad398f04de21ecb29
https://doi.org/10.1016/j.livres.2019.11.003

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Transarterial chemoembolization (TACE) combined with apatinib versus TACE combined with sorafenib in advanced hepatocellular carcinoma patients: a multicenter retrospective study

Autor: Binkui Li, Yun Zheng, Yanping Ma, Jiliang Qiu, Yunfei Yuan, Zining Xu, Guoying Wang, Zhiyu Qiu, Zhentao Yu, Lujun Shen, Wei He, Mengting Shi, Yi-Quan Jiang

Publikováno v: Ann Transl Med

BACKGROUND: The combination of transarterial chemoembolization (TACE) with sorafenib has demonstrated superior efficacy over sorafenib and TACE monotherapy in hepatocellular carcinoma (HCC). Apatinib, a new targeted agent, has been recently reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439ef01dfaadd2c3f2b0c432ee785ee7
https://pubmed.ncbi.nlm.nih.gov/33708910

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Autor: Jinhua Huang, Zi-Xian Wang, Wuguo Deng, Yinan Deng, Yang Yang, Xue Han, Xuxiazi Zou, Ming Zhong, Lujun Shen, Yi-Quan Jiang, Guihua Chen, Xin-Yi Liu

Publikováno v: Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e63ca33d6e5378a0fb0bd7dd8107bf7
https://doi.org/10.1080/2162402x.2021.1908010

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Investigating Cell-Cell Crosstalk in Pre- and Post- Programmed Cell Death-1 (PD-1) Targeted Therapy Tumours Using Single-Cell RNA-Sequencing Analysis

Autor: Zi-Xian Wang, Yi-Quan Jiang, Jinhua Huang, Guihua Chen, Xue Han, Xin-Yi Liu, Wuguo Deng, Yinan Deng, Lujun Shen, Yang Yang

Publikováno v: SSRN Electronic Journal.

Background: Currently, a significant proportion of cancer patients cannot benefit from programmed cell death-1 (PD-1) targeted therapy. An intractable problem exists regarding how to overcome the drug resistance. Methods: Single-cell RNA sequence dat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70838bbcce4635368f5ecccdab3f845b
https://doi.org/10.2139/ssrn.3716883

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