Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yi-Qiang Liang"'
Autor:
Fumihiko Takeuchi, Yi-Qiang Liang, Masato Isono, Michiko Tajima, Zong Hu Cui, Yoko Iizuka, Takanari Gotoda, Toru Nabika, Norihiro Kato
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 5 (2021)
Despite remarkable progress made in human genome-wide association studies, there remains a substantial gap between statistical evidence for genetic associations and functional comprehension of the underlying mechanisms governing these associations. A
Externí odkaz:
https://doaj.org/article/6a7b30442db64ccfbb761c89a4f06dc0
Autor:
Tadashi Okamura, Rieko Yanobu-Takanashi, Fumihiko Takeuchi, Masato Isono, Koichi Akiyama, Yukiko Shimizu, Motohito Goto, Yi-Qiang Liang, Ken Yamamoto, Tomohiro Katsuya, Akihiro Fujioka, Keizo Ohnaka, Ryoichi Takayanagi, Toshio Ogihara, Yukio Yamori, Norihiro Kato
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49055 (2012)
Background/objectiveThe CDKAL1 gene is among the best-replicated susceptibility loci for type 2 diabetes, originally identified by genome-wide association studies in humans. To clarify a physiological importance of CDKAL1, we examined effects of a gl
Externí odkaz:
https://doaj.org/article/300ce441f73e4252bb1dfceb572b9220
Autor:
Fumihiko Takeuchi, Yi-Qiang Liang, Hana Shimizu-Furusawa, Masato Isono, Mia Yang Ang, Kotaro Mori, Taizo Mori, Eiji Kakazu, Sachiyo Yoshio, Norihiro Kato
Publikováno v:
Life Science Alliance; Oct2023, Vol. 6 Issue 10, p1-19, 19p
Autor:
Fumihiko Takeuchi, Yi-Qiang Liang, Hana Shimizu-Furusawa, Masato Isono, Mia Yang Ang, Kotaro Mori, Taizo Mori, Eiji Kakazu, Sachiyo Yoshio, Norihiro Kato
BackgroundNon-alcoholic fatty liver disease (NAFLD) develops from fatty liver to steatohepatitis during which multiple cell types may play different roles. Aiming to understand the tissue composition of cell types, their gene expression and global ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1d18d89ea5e1a26487b807e3e4337a
https://doi.org/10.1101/2022.07.12.499681
https://doi.org/10.1101/2022.07.12.499681
Publikováno v:
Hypertension Research. 43:655-666
Cholesteryl ester transfer protein (CETP) mediates a step in reverse cholesterol transport, which channels cholesterol from peripheral tissues back to the liver. Mice and rats are CETP-deficient species, which assumedly contribute to rodent atheroscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd3e7356e9b148766da17a237775e22
https://doi.org/10.1038/s41440-020-0401-9
https://doi.org/10.1038/s41440-020-0401-9
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(2)
Certain classes of antihypertensive drug may exert specific, blood pressure (BP)-independent protective effects on end-organ damages such as left ventricular hypertrophy, although the overall evidence has not been definitive in clinical trials. To un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef129e0b03bcac19ab1003ebcec76af
https://pubmed.ncbi.nlm.nih.gov/34879704
https://pubmed.ncbi.nlm.nih.gov/34879704
Autor:
Zong Hu Cui, Masato Isono, Fumihiko Takeuchi, Norihiro Kato, Yoko Iizuka, Takanari Gotoda, Yi-Qiang Liang, Michiko Tajima, Toru Nabika
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 5 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms
article-version (VoR) Version of Record
Despite remarkable progress made in human genome-wide association studies, there remains a substantial gap between statistical evidence for genetic associations and functional comprehension of the underlying mechanisms governing these associations. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33af4277ebef3c07abd6b46ec4b92a77
http://dmm.biologists.org/content/14/5/dmm048090
http://dmm.biologists.org/content/14/5/dmm048090
Autor:
Lei Li, Yi-Qiang Liang, Tatsuya Sawamura, Hana Shimizu, Fumihiko Takeuchi, Norihiro Kato, Yasunari Matsuzaka, Akemi Kakino, Michiko Tajima, Tomoji Mashimo, Takehito Kaneko, Tomohisa Akamatsu, Masato Isono
Publikováno v:
Stroke. 51(6)
Background and Purpose— oxLDL (oxidized low-density lipoprotein) has been known for its potential to induce endothelial dysfunction and used as a major serological marker of oxidative stress. Recently, LOX-1 (lectin-like oxidized low-density lipopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88efab159da27d2146885317137cb944
https://pubmed.ncbi.nlm.nih.gov/32397936
https://pubmed.ncbi.nlm.nih.gov/32397936
Autor:
Zhi-Hao Wen, De-Qing Huang, Ming-Jian Huang, Chao-Xin Pan, Qing-Gao Wang, Yi-Qiang Liang, Yan Pang, Ya-Ping Cao, Qian-Yu Li
Publikováno v:
Journal of Hainan Medical University; Jul2021, Vol. 27 Issue 14, p1-6, 6p
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 22:455-480
Aim It is challenging to identify causal (or target) genes at individual loci detected using genome-wide association studies (GWAS). In order to follow up GWAS loci, we investigated functional genes at homologous loci identified using human lipid GWA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a5d1fee502b7a4b9b99ccec9ef6f33
https://doi.org/10.5551/jat.27706
https://doi.org/10.5551/jat.27706