Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yi-Ping Ye"'
Publikováno v:
Investigational New Drugs. 40:370-388
The Hedgehog/Glioma-associated oncogene homolog (HH/GLI) signaling pathway regulates self-renewal of rare and highly malignant cancer stem cells, which have been shown to account for the initiation and maintenance of tumor growth as well as for drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dc1e14a45adfd7dbd1e46b4e508bb9d
https://doi.org/10.1007/s10637-021-01187-2
https://doi.org/10.1007/s10637-021-01187-2
Publikováno v:
Pharmacological research. 169
The neuroactive steroid allopregnanolone (ALLO) is an endogenous positive allosteric modulator of GABA type A receptor (GABAAR), and the down-regulation of its biosynthesis have been attributed to the development of mood disorders, such as depression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3027063cd5aa1dd9291d8d0b82ad67
https://pubmed.ncbi.nlm.nih.gov/34019980
https://pubmed.ncbi.nlm.nih.gov/34019980
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 44(23)
This study aims to investigate the PPARγ agonists isolated from the aqueous extract of Siegesbeckia pubescens( SPA) and their anti-inflammatory activities in vitro. The 293 T cells transfected transiently with PPARγ recombinant plasmid were used as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eea1cf9f6630a1ed7f2a67943703fbe7
https://pubmed.ncbi.nlm.nih.gov/32237357
https://pubmed.ncbi.nlm.nih.gov/32237357
Publikováno v:
Phytochemistry Letters. 23:26-32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63cce30d4a74723b236637454fe9c57f
https://doi.org/10.1016/j.phytol.2017.11.007
https://doi.org/10.1016/j.phytol.2017.11.007
Publikováno v:
Bioorganic & Medicinal Chemistry. 39:116166
Constitutive activation of Hedgehog (Hh) pathway is intimately related with the occurrence and development of several malignancies, such as medulloblastoma (MB) and other tumors. Therefore, small molecular inhibitors of Hh pathway are urgently needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5e07c58befddcd44225b80517649bb
https://doi.org/10.1016/j.bmc.2021.116166
https://doi.org/10.1016/j.bmc.2021.116166
Autor:
Feng-Yang Chen, Hongxiang Sun, Li-Juan Gao, Li-Fei Zhou, Yi-Ping Ye, Wenhai Huang, Shi-Fang Xu, Jia-Wen Zhao, Shu-Juan Hao, Xiaoyu Li
Publikováno v:
European Journal of Pharmacology. 789:370-384
Stephanthraniline A (STA), a C21 steroid isolated from Stephanotis mucronata (Blanco) Merr., was previously shown to inhibit T cells activation and proliferation in vitro and in vivo. The purpose of this study was to further evaluate the in vivo immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4668201bf79bc9b82b6c60d411c4bf2c
https://doi.org/10.1016/j.ejphar.2016.06.022
https://doi.org/10.1016/j.ejphar.2016.06.022
Publikováno v:
Journal of Ethnopharmacology. 257:112677
Ethnopharmacological relevance The genus Albizia (Leguminosae) comprises about 150 species and some species have been used for the treatment of rheumatism, stomachache, cough, diarrhea, and wounds in traditional and local medicine. The aim of the rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f91a2ab8bb1e4ac59e563b68f44b75f
https://doi.org/10.1016/j.jep.2020.112677
https://doi.org/10.1016/j.jep.2020.112677
Autor:
Jia-Wen, Zhao, Feng-Yang, Chen, Li-Juan, Gao, Shi-Fang, Xu, Shu-Juan, Hao, Yi-Ping, Ye, Xiao-Yu, Li
Publikováno v:
Natural product communications. 11(12)
Two new 8, 14-seco skeleton C(21) steroidal aglycones, cynanbungeigenin A (1) and cynanbungeigenin B (2), were isolated from the hydrolyzed extract of the EtOAc soluble extract of the roots of Cynanchum bungei. Their structures were determined on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0285eb4faf06103a8b586c57361e70e2
https://pubmed.ncbi.nlm.nih.gov/30508336
https://pubmed.ncbi.nlm.nih.gov/30508336
Publikováno v:
Phytomedicine. 22:510-515
Objective The leaves and bark of Metasequoia glyptostroboides are used as anti-microbic, analgesic and anti-inflammatory drug for dermatic diseases in Chinese folk medicine. However, the pharmacological effects and material basis responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29cd62d058fc84669333ad1368ad62d
https://doi.org/10.1016/j.phymed.2015.03.006
https://doi.org/10.1016/j.phymed.2015.03.006
Autor:
Li-Juan Gao, Wen-Jing Huang, Shi-Fang Xu, Yang Wei, Xiaoyu Li, Li-Fei Zhou, Yi-Ping Ye, Wen-Fu Tan, Feng-Yang Chen
Publikováno v:
Cancer letters. 420
Uncontrolled excessive activation of Hedgehog (Hh) signaling pathway is linked to a number of human malignant tumorigenesis. To obtain valuable Hh pathway inhibitors from natural product, in present study, a pair of novel epimers, Cynanbungeigenin C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a10164fcc9421fb58d5e10a9ae4e42
https://pubmed.ncbi.nlm.nih.gov/29425683
https://pubmed.ncbi.nlm.nih.gov/29425683