Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Yi-Min Zheng"'
Autor:
Pei Li, Yajie Liu, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yi-Min Zheng, Claire Carlin, Joseph S. Bednash, Jeffrey C. Horowitz, Rama K. Mallampalli, Linda J. Saif, Eugene M. Oltz, Daniel Jones, Jianrong Li, Richard J. Gumina, Shan-Lu Liu
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTThe rapid evolution of SARS-CoV-2 variants presents a constant challenge to the global vaccination effort. In this study, we conducted a comprehensive investigation into two newly emerged variants, BA.2.87.1 and JN.1, focusing on their neutra
Externí odkaz:
https://doaj.org/article/95cbede0c59042fca721a9fccb79db49
Autor:
Jia-Cheng Lu, Lei-Lei Wu, Yi-Ning Sun, Xiao-Yong Huang, Chao Gao, Xiao-Jun Guo, Hai-Ying Zeng, Xu-Dong Qu, Yi Chen, Dong Wu, Yan-Zi Pei, Xian-Long Meng, Yi-Min Zheng, Chen Liang, Peng-Fei Zhang, Jia-Bin Cai, Zhen-Bin Ding, Guo-Huan Yang, Ning Ren, Cheng Huang, Xiao-Ying Wang, Qiang Gao, Qi-Man Sun, Ying-Hong Shi, Shuang-Jian Qiu, Ai-Wu Ke, Guo-Ming Shi, Jian Zhou, Yi-Di Sun, Jia Fan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Intratumoral immune status influences tumor therapeutic response, but it remains largely unclear how the status determines therapies for patients with intrahepatic cholangiocarcinoma. Here, we examine the single-cell transcriptional and TCR
Externí odkaz:
https://doaj.org/article/1395aad7bace40e0b84d6d1fe593d121
Autor:
Zhong-Chen Li, Jie Wang, He-Bin Liu, Yi-Min Zheng, Jian-Hang Huang, Jia-Bin Cai, Lei Zhang, Xin Liu, Ling Du, Xue-Ting Yang, Xiao-Qiang Chai, Ying-Hua Jiang, Zheng-Gang Ren, Jian Zhou, Jia Fan, De-Cai Yu, Hui-Chuan Sun, Cheng Huang, Feng Liu
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113877- (2024)
Summary: Combination therapy (lenvatinib/programmed death-1 inhibitor) is effective for treating unresectable hepatocellular carcinoma (uHCC). We reveal that responders have better overall and progression-free survival, as well as high tumor mutation
Externí odkaz:
https://doaj.org/article/373fb5f605da44d19f76ab1177c0032c
Autor:
Julia N. Faraone, Panke Qu, Negin Goodarzi, Yi-Min Zheng, Claire Carlin, Linda J. Saif, Eugene M. Oltz, Kai Xu, Daniel Jones, Richard J. Gumina, Shan-Lu Liu
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Immune evasion by SARS-CoV-2 paired with immune imprinting from monovalent mRNA vaccines has resulted in attenuated neutralizing antibody responses against Omicron subvariants. In this study, we characterized two new XBB variants rising in circulatio
Externí odkaz:
https://doaj.org/article/b692e73b9e114a7989eec498d6f2e331
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Purpose We aimed to study the association between adjusted mtDNA levels in human trophectoderm biopsy samples and the developmental potential of euploid and mosaic blastocysts. Methods We analyzed relative mtDNA levels in 2,814 blastocysts o
Externí odkaz:
https://doaj.org/article/41142f413d164305b6b0e64d58b64e02
Autor:
Julia N. Faraone, Panke Qu, Yi-Min Zheng, Claire Carlin, Daniel Jones, Ashish R. Panchal, Linda J. Saif, Eugene M. Oltz, Richard J. Gumina, Shan-Lu Liu
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113193- (2023)
Summary: The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to challenge the efficacy of vaccination efforts against coronavirus disease 2019 (COVID-19). The Omicron XBB lineage of SARS-CoV-2 has presented dramati
Externí odkaz:
https://doaj.org/article/cfda189123b9471392add9cb35e71aba
Autor:
Panke Qu, Julia N. Faraone, John P. Evans, Yi-Min Zheng, Claire Carlin, Mirela Anghelina, Patrick Stevens, Soledad Fernandez, Daniel Jones, Ashish R. Panchal, Linda J. Saif, Eugene M. Oltz, Baoshan Zhang, Tongqing Zhou, Kai Xu, Richard J. Gumina, Shan-Lu Liu
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112443- (2023)
Summary: Omicron subvariants continuingly challenge current vaccination strategies. Here, we demonstrate nearly complete escape of the XBB.1.5, CH.1.1, and CA.3.1 variants from neutralizing antibodies stimulated by three doses of mRNA vaccine or by B
Externí odkaz:
https://doaj.org/article/7a63990573e945a0aca2c8dcdaa8973d
Autor:
Panke Qu, John P. Evans, Chaitanya Kurhade, Cong Zeng, Yi-Min Zheng, Kai Xu, Pei-Yong Shi, Xuping Xie, Shan-Lu Liu
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT The rapid spread and strong immune evasion of the SARS-CoV-2 Omicron subvariants has raised serious concerns for the global COVID-19 pandemic. These new variants exhibit generally reduced fusogenicity and increased endosomal entry pathway ut
Externí odkaz:
https://doaj.org/article/64d9ebd5e9174140a944051f3ce76ca7
Autor:
Chao Gao, Si-wei Wang, Jia-cheng Lu, Xiao-qiang Chai, Yuan-cheng Li, Peng-fei Zhang, Xiao-yong Huang, Jia-bin Cai, Yi-min Zheng, Xiao-jun Guo, Guo-ming Shi, Ai-wu Ke, Jia Fan
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Background Kinase suppressor of Ras 2 (KSR2) is a regulator of MAPK signaling that is overactivated in most hepatocellular carcinoma (HCC). We sought to determine the role of KSR2 in HCC pathogenesis. Methods We tested the level of KSR2 in H
Externí odkaz:
https://doaj.org/article/1420ed705a324cb1a2f47b22f124007a
Autor:
Peng Liu, Si-Jia Sun, Ying-Jie Ai, Xu Feng, Yi-Min Zheng, Yun Gao, Jin-Ye Zhang, Lei Zhang, Yi-Ping Sun, Yue Xiong, Miao Lin, Hai-Xin Yuan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-11 (2022)
Abstract Increased glycolysis is a hallmark of tumor, which can provide tumor cells with energy and building blocks to promote cell proliferation. Recent studies have shown that not only the expression of glycolytic genes but also their subcellular l
Externí odkaz:
https://doaj.org/article/23611dc058cb4a4ca2ba58136cb8053d