Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yi-Min Ku"'
Publikováno v:
Journal of Pharmacy Practice. 18:422-431
The use of mycophenolate mofetil (MMF), in combination with cyclosporine (CsA) or tacrolimus (FK) and corticosteroids, has been shown to improve clinical outcomes through significant reduction in the incidence of acute rejection in solid organ transp
Publikováno v:
Clinical Pharmacology & Therapeutics. 68:478-486
Pharmacokinetic studies of intravenous and oral cyclosporine (cyclosporin) were performed in 22 healthy African American (n = 11) and white (n = 11) volunteers. Blood cyclosporine concentrations were measured by high performance liquid chromatography
Publikováno v:
Pharmacotherapy. 19:753-759
Dextromethorphan (DM) is metabolized in the body to dextrophan (DT) and 3-methoxymorphinan (3-MM) by cytochrome P450 (CYP) 2D6 and 3A4, respectively, and cyclosporine (CsA) is a known substrate of CYP3A4. We attempted to determine if the urine metabo
Autor:
Yi-Min Ku, David I. Min
Publikováno v:
Therapeutic Drug Monitoring. 20:219-223
This study aims to assess the predictability of individual tacrolimus (FK) concentrations at different time points for the area under the curve (AUC) and to find the best sampling time for the abbreviated AUC to predict the total body exposure of FK.
Publikováno v:
Journal of Pharmacy Technology. 12:58-61
Objective: To examine the stability of tacrolimus in a total parenteral nutrition (TPN) solution over 24 hours at room temperature. Study Method: Admixtures of tacrolimus 0.1 mg/mL in TPN, containing amino acids 4.25%, dextrose 25%, and electrolytes,
Autor:
Yi-Min Ku, Paul J. Perry, Ferdinand O. Ukah, Maureen Martin, David I. Min, Lawrence G. Hunsicker, Kay Ashton
Publikováno v:
Transplantation. 62:123-125
This study investigated the effect of grapefruit juice on cyclosporine A (CsA) bioavailability in 10 renal transplant patients. Under CsA steady state conditions, patients were randomly administered their usual dose of CsA with either 8 ounces of gra
Publikováno v:
Journal of clinical pharmacology. 41(3)
This study aims to determine the effect of grapefruit juice (GJ) on microemulsion cyclosporine (CsA) in 11 African American subjects, and it was compared to those in 11 Caucasian subjects. Each subject received two oral doses of CsA with water (W) or
Autor:
Yi Min Ku, Claudia Corwin, You Min Wu, David I. Min, Lawrence G. Hunsicker, Stephen C. Rayhill
Publikováno v:
Pharmacotherapy. 19(7)
A 38-year-old woman with type 1 diabetes underwent kidney-pancreas transplantation. Her postoperative course was complicated due to recurrent acute graft rejections and pancreatitis. After initial immunosuppression with microemulsion cyclosporine, my
Autor:
Yi-Min Ku
Publikováno v:
Journal of Pharmacy Practice; Dec2005, Vol. 18 Issue 6, p422-431, 10p
Publikováno v:
Journal of clinical pharmacology. 36(5)
A study was conducted to examine the effect of grapefruit juice on the disposition of quinidine sulfate and changes of QT intervals after oral administration to twelve healthy male volunteers. Participants received two oral doses of quinidine sulfate