Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Yi-Li Chen"'
Autor:
Yongmei Wang, Yi-Li Chen, Hui Xu, Gul E. Rana, Xiaorong Tan, Mengying He, Qingqing Jing, Qi Wang, Guifeng Wang, Zuoquan Xie, Chunhe Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHumanization is typically adopted to reduce the immunogenicity of murine antibodies generated by hybridoma technology when used in humans.MethodsTwo different strategies of antibody humanization are popularly employed, including “comple
Externí odkaz:
https://doaj.org/article/4de509a4348b4b1e9ee265d2f6b70fc5
Autor:
Hung-Wen Tsai, Yi-Li Chen, Chun-I Wang, Ching‑Chuan Hsieh, Yang-Hsiang Lin, Pei-Ming Chu, Yuh-Harn Wu, Yi-Ching Huang, Cheng-Yi Chen
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-19 (2023)
Abstract Background Hepatocellular carcinoma (HCC) accounts for almost 80% of all liver cancer cases and is the sixth most common cancer and the second most common cause of cancer-related death worldwide. The survival rate of sorafenib-treated advanc
Externí odkaz:
https://doaj.org/article/9487078003154bbba829185bf6e97f8d
Autor:
Xin‐Yuan Liu, Yi‐Li Chen, Guo‐Jian Liu, Xiang‐Nan Deng, Yue Cui, Jie Tan, Xing‐Chen Dong, Hua‐Ying Li, Gan‐Jun Chen, Zhi‐Min Ou, Chun‐He Wang
Publikováno v:
FEBS Open Bio, Vol 12, Iss 9, Pp 1644-1656 (2022)
Dinutuximab (ch14.18) was the first approved monoclonal antibody against the tumor‐associated antigen disialoganglioside GD2. Despite its success in treating neuroblastoma (NB), it triggers a significant amount of neuropathic pain in patients, poss
Externí odkaz:
https://doaj.org/article/81bf6d4c32d14a42b60844d317b002a4
Autor:
Xingchen Dong, Huanhuan Li, Min Pei, Jie Tan, Ganjun Chen, Santai Li, Zuobin Xie, Qi Wang, Guifeng Wang, Yi‐Li Chen, Chunhe Wang
Publikováno v:
FEBS Open Bio, Vol 12, Iss 7, Pp 1325-1335 (2022)
Current treatment options for diabetic neuralgia are limited and unsatisfactory. Tanezumab, a monoclonal antibody that blocks nerve growth factor (NGF) signaling, has been shown to be effective in relieving the clinical symptoms of osteoarthritis pai
Externí odkaz:
https://doaj.org/article/a9606ba2735548999bd7b89e87cd8e56
Publikováno v:
Plants, Vol 12, Iss 15, p 2880 (2023)
The advancement of mass spectrometry technologies has revolutionised plant metabolomics research by enabling the acquisition of raw metabolomics data. However, the identification, analysis, and visualisation of these data require specialised tools. E
Externí odkaz:
https://doaj.org/article/2c88df2963a347689510f7ea2a678d30
Autor:
Yuning Chen, Ya-Nan Zhang, Renhong Yan, Guifeng Wang, Yuanyuan Zhang, Zhe-Rui Zhang, Yaning Li, Jianxia Ou, Wendi Chu, Zhijuan Liang, Yongmei Wang, Yi-Li Chen, Ganjun Chen, Qi Wang, Qiang Zhou, Bo Zhang, Chunhe Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract The evolution of coronaviruses, such as SARS-CoV-2, makes broad-spectrum coronavirus preventional or therapeutical strategies highly sought after. Here we report a human angiotensin-converting enzyme 2 (ACE2)-targeting monoclonal antibody, 3
Externí odkaz:
https://doaj.org/article/35219e6c1dc04f9e9c101622932521d1
Autor:
Songlin Mu, Zhijuan Liang, Yongmei Wang, Wendi Chu, Yi‐Li Chen, Qi Wang, Guifeng Wang, Chunhe Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/2c491c0ad96e42348e50acb6e5888efb
Autor:
Wendi Chu, Hui Xu, Yanfei Wang, Yongle Xie, Yi‐Li Chen, Xiaorong Tan, Chenghao Huang, Guifeng Wang, Qi Wang, Wenxin Luo, Ningshao Xia, Meiyu Geng, Zuoquan Xie, Chunhe Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 4, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/3380a1567889485c9ccaf6fa9be24759
Autor:
Hong-Yun Zeng, He-Nan Bao, Yi-Li Chen, Ding-Kang Chen, Kun Zhang, Shuai-Kang Liu, La Yang, Yong-Kang Li, Nan Yao
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Ceramide synthases (CSs) produce ceramides from long-chain bases (LCBs). However, how CSs regulate immunity and cell death in Arabidopsis thaliana remains unclear. Here, we decipher the roles of two classes of CS, CSI (LAG1 HOMOLOG 2, LOH2) and CSII
Externí odkaz:
https://doaj.org/article/1a314ccdbe904084a628eec55932f263
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Sphingolipids are a class of membrane lipids that serve as vital structural and signaling bioactive molecules in organisms ranging from yeast to animals. Recent studies have emphasized the importance of sphingolipids as signaling molecules in the dev
Externí odkaz:
https://doaj.org/article/fe9cb6db875146cba667fdbb2dd18409