Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Yi-Kuo Yu"'
Autor:
Mehdi Hamaneh, Yi-Kuo Yu
Publikováno v:
Cancer Informatics, Vol 22 (2023)
Motivation: The PAM50 signature/method is widely used for intrinsic subtyping of breast cancer samples. However, depending on the number and composition of the samples included in a cohort, the method may assign different subtypes to the same sample.
Externí odkaz:
https://doaj.org/article/3f6d5e7938464bfeb40e872557769ad1
Autor:
Mehdi Hamaneh, Yi-Kuo Yu
Publikováno v:
Cancer Informatics, Vol 21 (2022)
Motivation: The precise diagnosis of the major subtypes, lung adenocarcinoma and lung squamous cell carcinoma, of non-small-cell lung cancer is of practical importance as some treatments are subtype-specific. However, in some cases diagnosis via the
Externí odkaz:
https://doaj.org/article/c26448a5c33f48b59d7ccd5a25ac0780
Autor:
Nahid Kondori, Amra Kurtovic, Beatriz Piñeiro-Iglesias, Francisco Salvà-Serra, Daniel Jaén-Luchoro, Björn Andersson, Gelio Alves, Aleksey Ogurtsov, Annika Thorsell, Johannes Fuchs, Timur Tunovic, Nina Kamenska, Anders Karlsson, Yi-Kuo Yu, Edward R. B. Moore, Roger Karlsson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Bloodstream infections (BSIs), the presence of microorganisms in blood, are potentially serious conditions that can quickly develop into sepsis and life-threatening situations. When assessing proper treatment, rapid diagnosis is the key; besides clin
Externí odkaz:
https://doaj.org/article/bd737f0c29ee4ee58af47563e061cd86
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Objective RAId is a software package that has been actively developed for the past 10 years for computationally and visually analyzing MS/MS data. Founded on rigorous statistical methods, RAId’s core program computes accurate E-values for
Externí odkaz:
https://doaj.org/article/a6bb175c924040f8a5c19792e8fc6a80
Autor:
Kai Wang, Anthony K. Guzman, Zi Yan, Shouping Zhang, Michael Y. Hu, Mehdi B. Hamaneh, Yi-Kuo Yu, Seda Tolu, Jinghang Zhang, Holly E. Kanavy, Kenny Ye, Boris Bartholdy, Eric E. Bouhassira
Publikováno v:
Cell Reports, Vol 26, Iss 10, Pp 2580-2592.e7 (2019)
Summary: Efficiency of reprogramming of human cells into induced pluripotent stem cells (iPSCs) has remained low. We report that individual adult human CD49f+ long-term hematopoietic stem cells (LT-HSCs) can be reprogrammed into iPSCs at close to 50%
Externí odkaz:
https://doaj.org/article/aed2c90697724a36a39ffa8c96951556
Autor:
Mehdi B Hamaneh, Yi-Kuo Yu
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220742 (2019)
Reprogramming of somatic cells to induced pluripotent stem cells, by overexpressing certain factors referred to as the reprogramming factors, can revolutionize regenerative medicine. To provide a coherent description of induced pluripotency from the
Externí odkaz:
https://doaj.org/article/7b6b08bef07f4b4e8660987851320f28
Autor:
Gelio Alves, Yi-Kuo Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91225 (2014)
Meta-analysis methods that combine P-values into a single unified P-value are frequently employed to improve confidence in hypothesis testing. An assumption made by most meta-analysis methods is that the P-values to be combined are independent, which
Externí odkaz:
https://doaj.org/article/944d835378594f3489ebd642daedb4ed
Autor:
Mehdi Bagheri Hamaneh, Yi-Kuo Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110936 (2014)
Identifying similar diseases could potentially provide deeper understanding of their underlying causes, and may even hint at possible treatments. For this purpose, it is necessary to have a similarity measure that reflects the underpinning molecular
Externí odkaz:
https://doaj.org/article/f3080a2785d342ba880652ac0f4ffa17
Autor:
Aleksandar Stojmirović, Yi-Kuo Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100098 (2014)
Organizing experimentally determined protein associations as a hierarchy can be a good approach to elucidating the content of protein complexes and the modularity of subcomplexes. Several challenges exist. First, intrinsically sticky proteins, such a
Externí odkaz:
https://doaj.org/article/cbc6479b473147b99770a68524aee6f8
Autor:
Gelio Alves, Yi-Kuo Yu
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22647 (2011)
Given the expanding availability of scientific data and tools to analyze them, combining different assessments of the same piece of information has become increasingly important for social, biological, and even physical sciences. This task demands, t
Externí odkaz:
https://doaj.org/article/3474a0020ea34c199caca8bdc5a7b233