Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yi-Jhu Lu"'
Autor:
Yi-Jhu Lu, Ya-Ju Wu, Lu-Jen Chen, Bor-Sheng Ko, Tzu-Ching Chang, Yi-Ju Wu, Shu-Man Liang, Yee-Jee Jan, Jun-Yang Liou
Publikováno v:
Toxins, Vol 13, Iss 8, p 568 (2021)
Chronic kidney disease (CKD) is a commonly occurring complex renal syndrome that causes overall mortality in many diseases. The clinical manifestations of CKD include renal tubulointerstitial fibrosis and loss of renal function. Metallothionein-I/II
Externí odkaz:
https://doaj.org/article/1a60749f8b6e4d3daa50957e839f7494
Autor:
Bor-Sheng Ko, Yi-Jhu Lu, Wen-Ling Yao, Tzu-An Liu, Shean-Shong Tzean, Tang-Long Shen, Jun-Yang Liou
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76320 (2013)
Leukemia stem cells (LSCs) are a limitless cell source for the initiation and maintenance of leukemia. Activation of the Wnt/β-catenin pathway is required for the survival and development of LSCs. Therefore, targeting β-catenin is considered a ther
Externí odkaz:
https://doaj.org/article/f3bd9e88841441e19b7787a73aca60d1
Autor:
Jun-Yang Liou, Lu-Jen Chen, Shu-Man Liang, Chih-Cheng Wu, Bor-Sheng Ko, Shaw-Fang Yet, Chih-Hui Chin, Yi-Jhu Lu, Yee-Jee Jan, Cheng-Chin Kuo
Publikováno v:
Aging (Albany NY)
Inflammation of the vascular microenvironment modulates distinct types of vascular cells, and plays important roles in promoting atherosclerosis, stenosis/restenosis, and vascular-related diseases. Nik-related kinase (Nrk), a member of the Ste20-type
Autor:
Bor-Sheng Ko, Shu-Man Liang, Yi-Ju Wu, Yi-Jhu Lu, Jun-Yang Liou, Linyi Chen, Shih-Sheng Jiang, Song-Kun Shyue, Yee-Jee Jan
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 6, Pp 1-13 (2019)
Cell Death and Disease, Vol 10, Iss 6, Pp 1-13 (2019)
Decreased expression of metallothionein-1 (MT-1) is associated with a poor prognosis in hepatocellular carcinoma (HCC). Here, we found that MT-1 expression was suppressed by 14-3-3ε, and MT-1 overexpression abolished 14-3-3ε-induced cell proliferat
Autor:
Yi-Ju Wu, Shyh-Chang Chen, John Wang, Shu-Man Liang, Bor-Sheng Ko, Yee-Jee Jan, Song-Kun Shyue, Jun-Yang Liou, Tzu-An Liu, Yi-Jhu Lu, Chia-Chia Liu
Publikováno v:
Oncotarget
14-3-3ε is overexpressed in hepatocellular carcinoma (HCC) and its expression significantly associates with a poor prognostic outcome. To uncover how 14-3-3ε contributes to the tumor progression of HCC, we investigated the potential downstream targ
Publikováno v:
Journal of Vascular Surgery. 59(2):483-491
BackgroundStroke patients with diabetes have a higher mortality rate, worse neurologic outcome, and more severe disability than those without diabetes. Results from clinical trials comparing the outcomes of stroke seen with intensive glycemic control
Autor:
Yung-Jen Chuang, Yee-Jee Jan, Yi-Ju Wu, Jun-Yang Liou, Bor-Sheng Ko, Yi-Ting Lin, Cheng-Chin Kuo, Yi-Jhu Lu, Shu-Man Liang, Song-Kun Shyue, Ya-Ju Wu
Publikováno v:
Cancers
Volume 11
Issue 2
Cancers, Vol 11, Iss 2, p 168 (2019)
Volume 11
Issue 2
Cancers, Vol 11, Iss 2, p 168 (2019)
Focal adhesion kinase (FAK) plays an important role in vascular development, including the regulation of endothelial cell (EC) adhesion, migration, proliferation, and survival. 3&rsquo
deoxyadenosine (cordycepin) is known to suppress FAK express
deoxyadenosine (cordycepin) is known to suppress FAK express
Autor:
Shaw-Fang Yet, Yi-Jhu Lu, Bor-Sheng Ko, Jun-Yang Liou, Yee-Jee Jan, Shu-Man Liang, Song-Kun Shyue
Publikováno v:
Scientific Reports
Maintaining stemness of leukemic stem cells (LSCs) and reciprocal interactions between leukemia and stromal cells support leukemic progression and resistance to chemotherapy. Targeting the niche-based microenvironment is thus a new approach for leuke
Autor:
Wen-Ling Yao, Tang-Long Shen, Shu-Man Liang, Yi-Jhu Lu, Tzu-An Liu, Shean-Shong Tzean, Jun-Yang Liou, Chia-Chia Liu, Bor-Sheng Ko
Publikováno v:
Anti-cancer agents in medicinal chemistry. 14(1)
Cordycepin, also known as 3-deoxyadenosine, is an analogue of adenosine extracted from the traditional Chinese medicine “Dong Chong Xia Cao”. Cordycepin is an active small molecular weight compound and is implicated in modulating multiple physiol
96
Ischemic stroke is a leading cause of death and disability in the worldwide and diabetes is the most rapidly increasing risk factor for stroke. Among patients with recent stroke, 70% have overt diabetes or prediabetes characterized by impaire
Ischemic stroke is a leading cause of death and disability in the worldwide and diabetes is the most rapidly increasing risk factor for stroke. Among patients with recent stroke, 70% have overt diabetes or prediabetes characterized by impaire
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/10772832012689658273