Continual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China

Autor: Yao Wang, Xin Fan, He Wang, Timothy Kudinha, Ya-Ning Mei, Fang Ni, Yu-Hong Pan, Lan-Mei Gao, Hui Xu, Hai-Shen Kong, Qing Yang, Wei-Ping Wang, Hai-Yan Xi, Yan-Ping Luo, Li-Yan Ye, Meng Xiao, China Hospital Invasive Fungal Surveillance Net (CHIF-NET) Study Group, Zi-Yong Sun, Zhong-Jv Chen, Ying-Chun Xu, Mei Kang, Yu-Ling Xiao, Kang Liao, Peng-Hao Guo, Hua Yu, Lin Yin, Da-Wen Guo, Lan-Ying Cui, Peng-Peng Liu, Hong He, Yan Jin, Hui Fan, Yun-Song Yu, Jie Lin, Ruo-Yu Li, Zhe Wan, Ling Ma, Shuai-Xian Du, Wen-En Liu, Yan-Ming Li, Tie-Li Zhou, Qing Wu, Xin-Lan Hu, Ning Li, Rong Zhang, Hong-Wei Zhou, Yi-Min Li, Dan-Hong Su, Qiang-Qiang Zhang, Li Li, Yun Xia, Li Yan, Zhi-Dong Hu, Na Yue, Yan Jiang, Zhi-Yong Liu, Yu-Ting Zheng, Wei Cao, Yun-Zhuo Chu, Fu-Shun Li, Yun Liu, Yuan-Hong Xu, Ying Huang, Wei Jia, Gang Li, Huo-Xiang Lv, Qing-Feng Hu, Xiu-Li Xu, Xiao-Yan Chen, Xiao-Ling Ma, Huai-Wei Lu, Yin-Mei Yang, Hui-Ling Chen, Jian-Sheng Huang, Hui Jing, Bin San, Yan Du, Hong-Jie Liang, Bin Yang, Yu-Lan Lin, Shan-Mei Wang, Qiong Ma, Hong-Mei Zhao, Li-Wen Liu, Qing Zhang, Fei Xia, Jin-Ying Wu, Mao-Li Yi, Xiang-Yang Chen, Wei-Ping Lu, Xiao-Yan Zeng, Jing Zhang, Jing Wang, Xiao-Guang Xiao, Jia-Yin Liang, Fan-Hua Huang, Gui-Ling Zou, Xue-Fei Du, Xiao-Ming Wang, Xu-Feng Ji, Yong Liu, Zhi-Jie Zhang, Yu-Xing Ni, Sheng-Yuan Zhao, Xiu-Lan Song, Chun-Yan Xu, Lin Meng, Xian-Feng Zhang, Jian-Hong Zhao, Hong-Lian Wei, Xue-Song Xu, Weil Li, Yu-Ping Wang, Mei Xu, Yun-Duo Wang, Jing Song, Tian-Pen Cui, Zhi-Min Hu, Ting-Yin Zhou, Hai-Qing Hu, Xiao-Min Xu, Shan-Yan Liang, Lin-Qiang Deng, Hui Chen, Xiao-Jun Sun, Hai-Bin Wang, Jian-Bang Kang, Tie-Ying Hou, Ping Ji, Na Chen, Wen-Jun Sui, Hai-Tong Gu, Xiao-Qin Ha, Yuan-Yuan Zhang, Shu-Feng Wang, Hong Lu, Yi-Hai Gu, Xuan Hou, Rong Tang, Yan-Yan Guo, Fei Huang, Long-Hua Hu, Xiao-Yan Hu, Juan Li, Lian-Hua Wei, Dan Liu, Yan-Qiu Han, Yi-Hui Yao, Jian-Sheng Wang, Jie Wang, Wei Li, Li-Ping Ning, Wei-Qing Song, Yu-Jie Wang, Liang Luan

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

BackgroundThere have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. Here we report on the epidemiology and antifungal susceptibility of C. tropicalis causing invasive candidiasis in China, fr

Externí odkaz: https://doaj.org/article/f5afcd8390ff4114824aab7f3902e06d

Integrated histological and molecular analyses of rebiopsy samples at osimertinib progression improve post-progression survivals: A single-center retrospective study

Autor: Jian Su, Yu-Er Gao, Jianxing Xiang, Zhi Xie, Hong-Hong Yan, Zhen Wang, Yi-Long Wu, Xuan Lin, Yi-Hui Yao, Jin-Ji Yang, Shi-Ling Zhang, Xu-Chao Zhang, Qing Zhou, Hai-Yan Tu, Analyn Lizaso, Jiang-Tao Cheng, Shuyin Chen, Hua-Jun Chen

Publikováno v: Lung Cancer. 150:97-106

Background This single-center retrospective cohort study sought to investigate the impact of rebiopsy analysis after osimertinib progression in improving the survival outcomes. Methods Eighty-nine patients with EGFR T790M-positive advanced NSCLC who

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dffa15fd3c737aa16a92b9c1111b25
https://doi.org/10.1016/j.lungcan.2020.10.010

Next-generation sequencing of tissue and liquid rebiopsy favors post-progression outcomes of EGFR T790M-positive NSCLC patients treated with osimertinib

Autor: Shi-Ling Zhang, Hong-Hong Yan, Xu-Chao Zhang, Hai-Yan Tu, Hua-Jun Chen, Yi-Long Wu, Jian Su, Qing Zhou, Yi-Hui Yao, Yu-Er Gao, Jiangtao Cheng, Zhen Wang, Jin-Ji Yang, Zhi Xie

Publikováno v: Journal of Clinical Oncology. 38:e21563-e21563

e21563 Background: Osimertinib is standard of care for patients with advanced non–small-cell lung cancer (NSCLC) carrying acquired epidermal growth factor receptor ( EGFR) T790M mutation. However, few studies have been conducted to investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa05f44bffe7cbce369881f80d7f3ef6
https://doi.org/10.1200/jco.2020.38.15_suppl.e21563

Clinical outcomes of NSCLC patients with acquired RET rearrangement after resistance to osimertinib

Autor: Jin Kang, Jia-Tao Cheng, Chang Lu, Hai-Yan Tu, Xu-Chao Zhang, Jin-Ji Yang, Qing Zhou, Xiang-Meng Li, Yi-Long Wu, Yi-Hui Yao

Publikováno v: Journal of Clinical Oncology. 37:e20626-e20626

e20626 Background: Resistance mechanisms to osimertinib have raised growing concerns, but those with acquired RET rearrangement is poorly characterized. Methods: We retrospectively identified advanced, EGFR-mutant NSCLC (non-small-cell lung cancer) p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0d0a98a43f94e1fc72af8ddeeea5153
https://doi.org/10.1200/jco.2019.37.15_suppl.e20626