Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Yi-Hua Qiu"'
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Dopamine is a neurotransmitter and has been found to regulate lymphocytes by acting on dopamine receptors (DRs). CD4+ T cells express all the five subtypes of DRs, D1R to D5R. Although CD4+ T cells have been involved in pathogenes
Externí odkaz:
https://doaj.org/article/fb782672aa384f2090c5caa07fd85713
Publikováno v:
Iranian Journal of Immunology, Vol 20, Iss 1, Pp 16-25 (2023)
Background: Recent research in our laboratory shows that CD4+ T cells express the β2 adrenergic receptor (β2-AR), and the sympathetic neurotransmitter norepinephrine regulates the function of T cells via β2-AR signaling. However, the immunoregulat
Externí odkaz:
https://doaj.org/article/42a1518c6f70439cbd5db4704b50ebd1
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2771-2777 (2022)
Interleukin 17A (IL-17A) was previously shown to be a key pro-inflammatory factor in diabetes mellitus and associated complications. However, the role of IL-17A in diabetic encephalopathy remains poorly understood. In this study, we established a mou
Externí odkaz:
https://doaj.org/article/d87f0454c67e43969e6e26a5a2925791
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Cerebellar ataxias (CAs) consist of a heterogeneous group of neurodegenerative diseases hallmarked by motor deficits and deterioration of the cerebellum and its associated circuitries. Neuroinflammatory responses are present in CA brain, but how neur
Externí odkaz:
https://doaj.org/article/c14f16cc2a1140e6b78d0305ce6c72fd
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 3, Pp 1240-1254 (2017)
Background/Aims: Regulatory T (Treg) cells have been associated with neuroprotection by inhibiting microglial activation in animal models of Parkinson's disease (PD), a progressive neurodegenerative disease characterized by dopaminergic neuronal loss
Externí odkaz:
https://doaj.org/article/d7e42b497fe445399aac7eaf23461c3a
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 22092-22108 (2014)
Transforming growth factor (TGF)-β1, a cytokine that can be expressed in the brain, is a key regulator of the brain’s responses to injury and inflammation. Alzheimer’s disease (AD), the most common neurodegenerative disorder, involves inflammato
Externí odkaz:
https://doaj.org/article/63be75df30f44227be6ae6bfa4737408
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116549 (2015)
Neuroinflammation has been reported to be associated with Alzheimer's disease (AD) pathogenesis. Neuroinflammation is generally considered as an outcome of glial activation; however, we recently demonstrated that T helper (Th)17 cells, a subpopulatio
Externí odkaz:
https://doaj.org/article/ac44bf2f9cbf40dea4aaa2a805bfcc0a
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75786 (2013)
Neuroinflammation, especially innate immunocyte-mediated neuroinflammation, has been reported to participate in pathogenesis of Alzheimer's disease (AD). However, the involvement of adaptive immune cells, such as CD4(+) T lymphocytes, in pathogenesis
Externí odkaz:
https://doaj.org/article/c1d78b5d98244c589c350dbdfca7dcb2
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65860 (2013)
Dopamine (DA), a neurotransmitter in the nervous system, has been shown to modulate immune function. We have previously reported that five subtypes of DA receptors, including D1R, D2R, D3R, D4R and D5R, are expressed in T lymphocytes and they are inv
Externí odkaz:
https://doaj.org/article/30522d6c35a547f1b0169c900942ab84
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 1, p 25 (2015)
Interleukin (IL)-10, an anti-inflammatory cytokine, is expressed in the brain and can inhibit microglial activation. Herein, we utilized lipopolysaccharide (LPS)-induced inflammatory Parkinson’s disease (PD) cell model to determine whether microgli
Externí odkaz:
https://doaj.org/article/34454dc343564c09bad384e070bd15e5