Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yi-Chun Isabella Tsai"'
Autor:
Sandra Kümper, H. Christian Eberl, Katrin Rittinger, Chun-wa Chung, Daniel Thomas, Henrik Johansson, David House, Yi-Chun Isabella Tsai, Luigi Martino, Marcel Muelbaier, Ken G. M. Fantom
Publikováno v:
Journal of the American Chemical Society
Modification of proteins with polyubiquitin chains is a key regulatory mechanism to control cellular behavior and alterations in the ubiquitin system are linked to many diseases. Linear (M1-linked) polyubiquitin chains play pivotal roles in several c
Autor:
Jane E Clarkson, David P. Dixon, David House, Stephen R. Martin, Chun-wa Chung, Katrin Rittinger, Yi-Chun Isabella Tsai, Henrik Johansson
Publikováno v:
Cell Chemical Biology
Summary Protein ubiquitination plays a key role in the regulation of cellular processes, and misregulation of the ubiquitin system is linked to many diseases. So far, development of tool compounds that target enzymes of the ubiquitin system has been