Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Yi-Chen Zhang"'
Autor:
Wei-Chi Luo, Shi-Qi Mei, Zi-Jian Huang, Zhi-Hong Chen, Yi-Chen Zhang, Ming-Yi Yang, Jia-Qi Liu, Jing-Yan Xu, Xiao-Rong Yang, Ri-Wei Zhong, Li-Bo Tang, Lin-Xi Yin, Yu Deng, Ying-Long Peng, Chang Lu, Bao-Long Chen, Dong-Xian Ke, Hai-Yan Tu, Jin-Ji Yang, Chong-Rui Xu, Yi-Long Wu, Qing Zhou
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The effects of gut microbiota and metabolites on the responses to immune checkpoint inhibitors (ICIs) in advanced epidermal growth factor receptor (EGFR) wild-type non-small cell lung cancer (NSCLC) have been studied. However, the
Externí odkaz:
https://doaj.org/article/09696509dfd34aa9a776fab02e6b047a
Autor:
Xue-Wu Wei, Chang Lu, Yi-Chen Zhang, Xue Fan, Chong-Rui Xu, Zhi-Hong Chen, Fen Wang, Xiao-Rong Yang, Jia-Yi Deng, Ming-Yi Yang, Qing Gou, Shi-Qi Mei, Wei-Chi Luo, Ri-Wei Zhong, Wen-Zhao Zhong, Jin-Ji Yang, Xu-Chao Zhang, Hai-Yan Tu, Yi-Long Wu, Qing Zhou
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTMetabolism reprogramming within the tumor microenvironment (TME) can have a profound impact on immune cells. Identifying the association between metabolic phenotypes and immune cells in lung adenocarcinoma (LUAD) may reveal mechanisms of resi
Externí odkaz:
https://doaj.org/article/69ff1c8e561c44988808d82daaa7d78f
Autor:
Xue Chen, Ying Wang, Jia-Nan Wang, Yi-Chen Zhang, Ye-Ran Zhang, Ru-Xu Sun, Bing Qin, Yuan-Xin Dai, Hong-Jing Zhu, Jin-Xiang Zhao, Wei-Wei Zhang, Jiang-Dong Ji, Song-Tao Yuan, Qun-Dong Shen, Qing-Huai Liu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 2, Pp 294-318 (2024)
Abstract Diabetic retinopathy (DR) is a leading cause of irreversible vision loss in working-age populations. Fat mass and obesity-associated protein (FTO) is an N6-methyladenosine (m6A) demethylase that demethylates RNAs involved in energy homeostas
Externí odkaz:
https://doaj.org/article/6a40c1bfa3554e66b172849242c8d92f
Autor:
Jun-Wei Su, Cheng-Di Weng, Xiao-Cheng Lin, Mei-Mei Fang, Xiao Xiao, Yi-Chen Zhang, Xu-Chao Zhang, Jian Su, Chong-Rui Xu, Hong-Hong Yan, Hua-Jun Chen, Yi-Long Wu, Jin-Ji Yang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Mesenchymal–epithelial transition ( MET ) amplification is a crucial oncogenic driver and a resistance mechanism to epidermal growth factor receptor tyrosine kinase inhibitors (TKIs) of non-small-cell lung cancer (NSCLC). Fluorescence i
Externí odkaz:
https://doaj.org/article/0ef134b3e84a4a9f9ebf044f8db4c295
Autor:
Hai‐Yan Tu, Kai Yin, Xiaotian Zhao, E‐E Ke, Si‐Pei Wu, Yang‐Si Li, Mei‐Mei Zheng, Si‐Yang Maggie Liu, Chong‐Rui Xu, Yue‐Li Sun, Jia‐Xin Lin, Xiao‐Yan Bai, Yi‐Chen Zhang, Qing Zhou, Jin‐Ji Yang, Wen‐Zhao Zhong, Bing‐Chao Wang, Xu‐Chao Zhang, Dongqin Zhu, Lingling Yang, Qiuxiang Ou, Yi‐Long Wu
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1581-1594 (2023)
The efficacy of immunotherapy in advanced HER2‐mutated non‐small‐cell lung cancer (NSCLC) remains incomprehensively studied. A total of 107 NSCLC patients with de novo HER2 mutations were retrospectively studied at Guangdong Lung Cancer Institu
Externí odkaz:
https://doaj.org/article/d5aadd22e14b45079cd59c661d0f474c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immune checkpoint inhibitors (ICIs), especially anti-programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) antibodies, have made dramatic progress in the treatment of lung cancer, especially for patients with cancers not driven by oncogenes. Ho
Externí odkaz:
https://doaj.org/article/e04b0aaab54a4f96a61ae575b86b5c63
Autor:
Xi Cao, Ting-Ting Shi, Chuan-Hai Zhang, Wan-Zhu Jin, Li-Ni Song, Yi-Chen Zhang, Jing-Yi Liu, Fang-Yuan Yang, Charles N Rotimi, Aimin Xu, Jin-Kui Yang
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/0a98677da82b4528bfcba5837ed80ae4
Autor:
Si‐Yang Liu, Jia‐Ying Zhou, Wen‐Feng Li, Hao Sun, Yi‐Chen Zhang, Hong‐Hong Yan, Zhi‐Hong Chen, Chun‐Xiang Chen, Jun‐Yi Ye, Jin‐Ji Yang, Qing Zhou, Xu‐Chao Zhang, Yi‐Long Wu
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 1, Pp 337-345 (2020)
Abstract Background In previous studies, the predictive role of BIM deletion polymorphism with respect to responses to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) has been controversial. The potential reasons for these i
Externí odkaz:
https://doaj.org/article/7dcc8de355ce485a84faf5181d3fa486
Autor:
Xi Cao, Ting-Ting Shi, Chuan-Hai Zhang, Wan-Zhu Jin, Li-Ni Song, Yi-Chen Zhang, Jing-Yi Liu, Fang-Yuan Yang, Charles N Rotimi, Aimin Xu, Jin-Kui Yang
Publikováno v:
eLife, Vol 11 (2022)
Identification of key regulators of energy homeostasis holds important therapeutic promise for metabolic disorders, such as obesity and diabetes. ACE2 cleaves angiotensin II (Ang II) to generate Ang-(1-7) which acts mainly through the Mas1 receptor.
Externí odkaz:
https://doaj.org/article/c970ae0f3da243d49bac27f104caddbe
Autor:
Xi Cao, Xin-Meng Lu, Xiu Tuo, Jing-Yi Liu, Yi-Chen Zhang, Li-Ni Song, Zhi-Qiang Cheng, Jin-Kui Yang, Zhong Xin
Publikováno v:
Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-8 (2019)
Abstract Objective Endoplasmic reticulum (ER) stress and mitochondrial function affected intramuscular fat accumulation. However, there is no clear evident on the effect of the regulation of ER stress and mitochondrial function by Angiotensin-convert
Externí odkaz:
https://doaj.org/article/d4c39bd367f4476a853da3914fbc105d