Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Yi-Chao Zheng"'
Autor:
Junyu Wu, Guoyi Tang, Chien-Shan Cheng, Ranna Yeerken, Yau-Tuen Chan, Zhiwen Fu, Yi-Chao Zheng, Yibin Feng, Ning Wang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-27 (2024)
Abstract Hepatic, biliary, and pancreatic cancer pose significant challenges in the field of digestive system diseases due to their highly malignant nature. Traditional Chinese medicine (TCM) has gained attention as a potential therapeutic approach w
Externí odkaz:
https://doaj.org/article/867c45ebbbcd4f019051d6418fc38d44
Autor:
MAA Mamun, Ying Liu, Yin-Ping Geng, Yi-Chao Zheng, Ya Gao, Jian-Gang Sun, Long-Fei Zhao, Li-Juan Zhao, Hong-Min Liu
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Neddylation is the writing of monomers or polymers of neural precursor cells expressed developmentally down-regulated 8 (NEDD8) to substrate. For neddylation to occur, three enzymes are required: activators (E1), conjugators (E2), and ligato
Externí odkaz:
https://doaj.org/article/71c327e1d8c144daa2fb53f4e7f00f0f
Autor:
M A A Mamun, Yu Zhang, Jin-Yuan Zhao, Dan-Dan Shen, Ting Guo, Yi-Chao Zheng, Li-Juan Zhao, Hong-Min Liu
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-18 (2023)
Abstract Dysregulation of various cells in the tumor microenvironment (TME) causes immunosuppressive functions and aggressive tumor growth. In combination with immune checkpoint blockade (ICB), epigenetic modification-targeted drugs are emerging as a
Externí odkaz:
https://doaj.org/article/6534692e6a934b02adba820e03bdc48a
Autor:
Dandan Shen, Bo Wang, Ya Gao, Lijuan Zhao, Yaping Bi, Jinge Zhang, Ning Wang, Huiqin Kang, Jingru Pang, Ying Liu, Luping Pang, Zhe-Sheng Chen, Yi-Chao Zheng, Hong-Min Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 5, Pp 2193-2205 (2022)
N6-Methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA, playing critical role in various bioprocesses. Like other epigenetic modifications, m6A modification can be catalyzed by the methyltransferase complex and erased
Externí odkaz:
https://doaj.org/article/98247e8d5ae54b518d2fddda30b18034
Autor:
Dan-Dan Shen, Jing-Ru Pang, Ya-Ping Bi, Long-Fei Zhao, Yin-Rui Li, Li-Juan Zhao, Ya Gao, Bo Wang, Ning Wang, Liuya Wei, Huiqin Guo, Hong-Min Liu, Yi-Chao Zheng
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Histone lysine-specific demethylase 1 (LSD1) expression has been shown to be significantly elevated in gastric cancer (GC) and may be associated with the proliferation and metastasis of GC. It has been reported that LSD1 repressed
Externí odkaz:
https://doaj.org/article/8e174da3639944fca2b165b40cea5f06
Autor:
Yuanjun Lu, Yau-Tuen Chan, Hor-Yue Tan, Cheng Zhang, Wei Guo, Yu Xu, Rakesh Sharma, Zhe-Sheng Chen, Yi-Chao Zheng, Ning Wang, Yibin Feng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Abstract Background Drug resistance to sorafenib greatly limited the benefits of treatment in patients with hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) participate in the development of drug resistance. The key miRNA regulators related to the
Externí odkaz:
https://doaj.org/article/c6716c82b15d4a1198f87fe713035cd7
Autor:
Long-Fei Zhao, Jin-Ge Zhang, Feng-Yu Qi, Wei-Yan Hou, Yin-Rui Li, Dan-Dan Shen, Li-Juan Zhao, Lin Qi, Hong-Min Liu, Yi-Chao Zheng
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1068-1076 (2022)
Sex differences are evident in the incidence and mortality of diverse cancers. With the development of personalized approaches in cancer treatment, the impact of sex differences has not been systematically incorporated into preclinical and clinical c
Externí odkaz:
https://doaj.org/article/d955467a03b8423b90180d92d22a8a7b
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/c4e60ac35793459ca8fed9ee4adf2d4d
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Ubiquitin-conjugating enzyme E2 M (UBE2M) and ubiquitin-conjugating enzyme E2 F (UBE2F) are the two NEDD8-conjugating enzymes of the neddylation pathway that take part in posttranslational modification and change the activity of target prote
Externí odkaz:
https://doaj.org/article/6166adac24e84375bef1b03902505d05
Autor:
Yi-Chao Zheng, Long-Zhen Wang, Li-Jie Zhao, Li-Juan Zhao, Qian-Na Zhan, Jin-Lian Ma, Bin Zhang, Meng-Meng Wang, Zhi-Ru Wang, Jin-Feng Li, Ying Liu, Zhe-Sheng Chen, Dan-Dan Shen, Xue-Qi Liu, Meng Ren, Wen-Lei Lv, Wen Zhao, Ying-Chao Duan, Hong-Min Liu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 1, Pp 185-193 (2016)
Background/Aims: Human SIRT1 is reported to be involved in tumorgenesis, mainly due to its modulating effect on p53 by deacetylation on lysine382. A large quantity of SIRT1 inhibitors was applied in chemotherapeutic study, but few of them were applie
Externí odkaz:
https://doaj.org/article/b5950129454c4ef5b1fd2a5ca7ffddfa