Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Yi-Chao Lee"'
Autor:
Christine Chin-jung Hsieh, Yu-Chun Lo, Hsin-Hui Wang, Hsin-Ying Shen, You-Yin Chen, Yi-Chao Lee
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Tuberous sclerosis complex (TSC) is a genetic disease that causes benign tumors and dysfunctions in many organs, including the brain. Aside from the brain malformations, many individuals with TSC exhibit neuropsychiatric symptoms. Among thes
Externí odkaz:
https://doaj.org/article/a48f3e7ef6f041c48905c4ead522ee93
Autor:
Hsin-Chuan Lin, Yung-Hao Ching, Chi-Chen Huang, Ping-Chieh Pao, Yi-Hua Lee, Wen-Chang Chang, Tzu-Jen Kao, Yi-Chao Lee
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Abstract Background Promyelocytic leukemia zinc finger (Plzf), a transcriptional regulator involved in a lot of important biological processes during development, has been implied to maintain neural stem cells and inhibit their differentiation into n
Externí odkaz:
https://doaj.org/article/9ae4e5a8016c47c3a8950a02088b3e76
Autor:
Yi-Chao Lee, Wan-Chen Huang, Jiann-Her Lin, Tzu-Jen Kao, Hui-Ching Lin, Kuen-Haur Lee, Hsin-Chuan Lin, Che-Kun James Shen, Wen-Chang Chang, Chi-Chen Huang
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-17 (2018)
Abstract Background The brain predominantly expressed RING finger protein, Znf179, is known to be important for embryonic neuronal differentiation during brain development. Downregulation of Znf179 has been observed in motor neurons of adult mouse mo
Externí odkaz:
https://doaj.org/article/7f3fe636c1a9433494d9cf7962b1d9ce
Autor:
Chung-Che Wu, Pin-Tse Lee, Tzu-Jen Kao, Szu-Yi Chou, Ruei-Yuan Su, Yi-Chao Lee, Shiu-Hwa Yeh, Jing-Ping Liou, Tsung-I Hsu, Tsung-Ping Su, Cheng-Keng Chuang, Wen-Chang Chang, Jian-Ying Chuang
Publikováno v:
Redox Biology, Vol 19, Iss , Pp 74-80 (2018)
The accumulation of reactive oxygen species (ROS) commonly occurs during normal aging and during some acute/chronic progressive disorders. In order to avoid oxidative damage, scavenging of these radicals is important. Previously, we identified zinc f
Externí odkaz:
https://doaj.org/article/391fa9488de0464ea6a09ab351cb1bb0
Autor:
Yuan-Chin Tsai, Tao Zeng, Wassim Abou-Kheir, Hsiu-Lien Yeh, Juan Juan Yin, Yi-Chao Lee, Wei-Yu Chen, Yen-Nien Liu
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-12 (2018)
Abstract Background ETS variant gene 6 (ETV6) is a putative tumor suppressor and repressed by epidermal growth factor receptor (EGFR) signaling in prostate cancer. Since EGFR antagonists seem ineffective in castration-resistant prostate cancer (CRPC)
Externí odkaz:
https://doaj.org/article/bcc7075fd05c42819df65e50360b5198
Autor:
Min-Ru Ho, Tsung-Ting Tsai, Chia-Ling Chen, Ming-Kai Jhan, Cheng-Chieh Tsai, Yi-Chao Lee, Chun-Han Chen, Chiou-Feng Lin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Dengue virus (DENV) infection in neuronal cells was speculated to trigger neuropathy. Herein, we determined the blockade of DENV infection by targeting endocytic pathways in vitro and in vivo. In DENV-infected mouse brains, we previously sho
Externí odkaz:
https://doaj.org/article/9000d0df5a274de08cebf48ccb2294cd
Autor:
Jian-Ying Chuang, Tzu-Jen Kao, Shu-Hui Lin, An-Chih Wu, Pin-Tse Lee, Tsung-Ping Su, Shiu-Hwa Yeh, Yi-Chao Lee, Chung-Che Wu, Wen-Chang Chang
Publikováno v:
Redox Biology, Vol 11, Iss , Pp 135-143 (2017)
After sudden traumatic brain injuries, secondary injuries may occur during the following days or weeks, which leads to the accumulation of reactive oxygen species (ROS). Since ROS exacerbate brain damage, it is important to protect neurons against th
Externí odkaz:
https://doaj.org/article/7f16fa2978d04b0aae7efe54ceb3bb84
Autor:
Ming-Kai Jhan, Tsung-Ting Tsai, Chia-Ling Chen, Cheng-Chieh Tsai, Yi-Lin Cheng, Yi-Chao Lee, Chiung-Yuan Ko, Yee-Shin Lin, Chih-Peng Chang, Liang-Tzung Lin, Chiou-Feng Lin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Activated microglial cells are present in dengue virus (DENV)-infected brains; however, the possible effects of DENV on microglia remain unclear. Here, we demonstrated DENV caused infection, including viral entry, RNA replication, viral prot
Externí odkaz:
https://doaj.org/article/e17c7c248ff54c3b94756749756ab941
Publikováno v:
Data in Brief, Vol 4, Iss C, Pp 235-238 (2015)
The data in this article is related to the research article entitled, “Targeting of Multiple Oncogenic Signaling Pathways by Hsp90 Inhibitor Alone or in Combination with Berberine for Treatment of Colorectal Cancer” [1]. Overexpression of survivi
Externí odkaz:
https://doaj.org/article/cf21b5cdc482493bafed01b7857645c2
Autor:
Han-Fang Wu, Yi-Ju Chen, Su-Zhen Wu, Chi-Wei Lee, I-Tuan Chen, Yi-Chao Lee, Chi-Chen Huang, Chung-Hsi Hsing, Chih-Wei Tang, Hui-Ching Lin
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Epoxyeicosatrienoic acids (EETs) are derived from arachidonic acid and metabolized by soluble epoxide hydrolase (sEH). The role of EETs in synaptic function in the central nervous system is still largely unknown. We found that pharmacological inhibit
Externí odkaz:
https://doaj.org/article/ef3d991706ae413fa6ff50506c182736