B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis

Autor: Tzu-Hui Hsu, Yu-Chan Chang, Yi-Yuan Lee, Chi-Long Chen, Michael Hsiao, Fan-Ru Lin, Li-Han Chen, Chun-Hung Lin, Takashi Angata, Fu-Tong Liu, Kuo-I Lin

Publikováno v: Cell Death and Disease, Vol 15, Iss 9, Pp 1-12 (2024)

Abstract Transforming growth factor (TGF)-β signaling is critical for epithelial-mesenchymal transition (EMT) and colorectal cancer (CRC) metastasis. Disruption of Smad-depednent TGF-β signaling has been shown in CRC cells. However, TGF-β receptor

Externí odkaz: https://doaj.org/article/5c06befb64fc4da281f145e65c4f03c0

Nipple-areolar complex (NAC) or skin flap ischemia necrosis post nipple-sparing mastectomy (NSM)—analysis of clinicopathologic factors and breast magnetic resonance imaging (MRI) features

Autor: Hung-Wen Lai, Yi-Yuan Lee, Shou-Tung Chen, Chiung-Ying Liao, Tsung-Lin Tsai, Dar-Ren Chen, Yuan-Chieh Lai, Wen-Pin Kao, Wen-Pei Wu

Publikováno v: World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-13 (2023)

Abstract Background The purpose of this study is to identify clinicopathologic factors and/or preoperative MRI vascular patterns in the prediction of ischemia necrosis of the nipple-areola complex (NAC) or skin flap post nipple-sparing mastectomy (NS

Externí odkaz: https://doaj.org/article/5389dec4022543d8bd2ac5969a7a0309

Data from Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-cell Receptor Signaling in Chronic Lymphocytic Leukemia

Autor: Kuo-I Lin, Yu-Ju Chen, Hwei-Fang Tien, Takashi Angata, Yi-Yuan Lee, Margarita Zamanova, Chi-Yuan Yao, Liang-In Lin, Kuen-Tyng Lin, Shao-Hsing Weng, Ho-Yang Tsai, Shang-Ju Wu, Hsin-Yi Wu, Jung-Lin Wu

Application of B-cell receptor (BCR) pathway inhibitor ibrutinib for chronic lymphocytic leukemia (CLL) is a major breakthrough, yet the downstream effects following inhibition of BCR signaling and during relapse await further clarification. By compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c11b04b681d0a0ba9cfea8f67f9c85a
https://doi.org/10.1158/1541-7786.c.6545424.v1

Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-cell Receptor Signaling in Chronic Lymphocytic Leukemia

Autor: Jung-Lin Wu, Hsin-Yi Wu, Shang-Ju Wu, Ho-Yang Tsai, Shao-Hsing Weng, Kuen-Tyng Lin, Liang-In Lin, Chi-Yuan Yao, Margarita Zamanova, Yi-Yuan Lee, Takashi Angata, Hwei-Fang Tien, Yu-Ju Chen, Kuo-I Lin

Publikováno v: Molecular Cancer Research. 20:1222-1232

Application of B-cell receptor (BCR) pathway inhibitor ibrutinib for chronic lymphocytic leukemia (CLL) is a major breakthrough, yet the downstream effects following inhibition of BCR signaling and during relapse await further clarification. By compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a22505cc5e66212ef289a0706f4c119
https://doi.org/10.1158/1541-7786.mcr-21-0722

A community resource for paired genomic and metabolomic data mining

Autor: Lars Ridder, Tim S. Bugni, Jamshid Amiri Moghaddam, Florian Huber, Elke Dittmann, Kelly C. Weldon, Louis-Félix Nothias, Douglas Sweeney, Mingxun Wang, Paul R. Jensen, Letícia V. Costa-Lotufo, Christine Beemelmanns, Katherine R. Duncan, Nadine Ziemert, Xuanji Li, Dulce G. Guillén Matus, Chao Du, Neha Garg, Jae Seoun Hur, Elizabeth I. Parkinson, Raphael Reher, Nicholas J. Tobias, Alex A. Blacutt, Emily C Pierce, Michelle Schorn, J. Michael Beman, Simon Rogers, María Victoria Berlanga-Clavero, Martin Baunach, Fan Zhang, Deepa D. Acharya, Harald Gross, Hamada Saad, M. Caroline Roper, Anna Edlund, Jason M. Crawford, Daniel Petras, Alexandra Calteau, Benjamin-Florian Hempel, Seoung Rak Lee, Max Crüsemann, Neil L. Kelleher, Hosein Mohimani, David P. Fewer, Shaurya Chanana, Carmen Saenz, Lena Gerwick, Ki-Hyun Kim, Roderich D. Süssmuth, Jörn Piel, Diego Romero, Marnix H. Medema, Anelize Bauermeister, Christopher Drozd, Regan J. Thomson, Anne Boullie, Michael W. Mullowney, Karine Pires, Andrew C. McAvoy, Alexander A. Aksenov, Saefuddin Aziz, Raquel Castelo-Branco, Julia M. Gauglitz, Mitchell N. Muskat, Bart Cuypers, Emily C. Gentry, Yi Yuan Lee, Eric J. N. Helfrich, Tam Dang, Pieter C. Dorrestein, Liu Cao, Rachel J. Dutton, Gilles P. van Wezel, Helge B. Bode, Margherita Sosio, Asker Daniel Brejnrod, Gajender Aleti, Leonard Kaysser, Amaro E. Trindade-Silva, Willam W. Metcalf, Irina Koester, Tiago Leao, Katherine D. Bauman, Jessica C. Little, Evgenia Glukhov, Ellis C. O’Neill, Justin J. J. van der Hooft, Alyssa M. Demko, Alexander B. Chase, Marc G. Chevrette, Bradley S. Moore, Christian Martin H, Kapil Tahlan, Cameron R. Currie, Allegra T. Aron, Muriel Gugger, Kyo Bin Kang, Víctor J. Carrión, Michael J. Rust, Gabriele M. König, Carlos Molina-Santiago, Søren J. Sørensen, Marianna Iorio, Jean-Claude Dujardin, Daniel Männle, Chung Sub Kim, Laura M. Sanchez, Katherine N. Maloney, Stefan Verhoeven, Tristan de Rond

Publikováno v: Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2021, ⟨10.1038/s41589-020-00724-z⟩
Nature Chemical Biology 17 (2021) 4
Nature Chemical Biology, 17(4), 363-368
Nature Chemical Biology, 17(4), 363-368. Nature Publishing Group
Nat Chem Biol
Schorn, M A, Verhoeven, S, Ridder, L, Huber, F, Acharya, D D, Aksenov, A A, Aleti, G, Moghaddam, J A, Aron, A T, Aziz, S, Bauermeister, A, Bauman, K D, Baunach, M, Beemelmanns, C, Beman, J M, Berlanga-Clavero, M V, Blacutt, A A, Bode, H B, Boullie, A, Brejnrod, A, Bugni, T S, Calteau, A, Cao, L, Carrión, V J, Castelo-Branco, R, Chanana, S, Chase, A B, Chevrette, M G, Costa-Lotufo, L V, Crawford, J M, Currie, C R, Cuypers, B, Dang, T, de Rond, T, Demko, A M, Dittmann, E, Du, C, Drozd, C, Dujardin, J-C, Dutton, R J, Edlund, A, Fewer, D P, Garg, N, Gauglitz, J M, Gentry, E C, Gerwick, L, Glukhov, E, Gross, H, Gugger, M, Matus, D G G, Helfrich, E J N, Hempel, B-F, Hur, J-S, Iorio, M, Jensen, P R, Kang, K B, Kaysser, L, Kelleher, N L, Kim, C S, Kim, K H, Koester, I, König, G M, Leao, T, Lee, S R, Lee, Y-Y, Li, X, Little, J C, Maloney, K N, Männle, D, Martin H., C, McAvoy, A C, Metcalf, W W, Mohimani, H, Molina-Santiago, C, Moore, B S, Mullowney, M W, Muskat, M, Nothias, L-F, O'Neill, E C, Parkinson, E I, Petras, D, Piel, J, Pierce, E C, Pires, K, Reher, R, Romero, D, Roper, M C, Rust, M, Saad, H, Saenz, C, Sanchez, L M, Sørensen, S J, Sosio, M, Süssmuth, R D, Sweeney, D, Tahlan, K, Thomson, R J, Tobias, N J, Trindade-Silva, A E, van Wezel, G P, Wang, M, Weldon, K C, Zhang, F, Ziemert, N, Duncan, K R, Crüsemann, M, Rogers, S, Dorrestein, P C, Medema, M H & van der Hooft, J J J 2021, ' A community resource for paired genomic and metabolomic data mining ', Nature Chemical Biology, vol. 17, no. 4, pp. 363-368 . https://doi.org/10.1038/s41589-020-00724-z
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Chemical Biology, 2021, ⟨10.1038/s41589-020-00724-z⟩
Nature chemical biology

International audience; Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)genome data, aiding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bab3cd944ad174c6905009e2841f0d
https://hal-pasteur.archives-ouvertes.fr/pasteur-03153704/document