Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yi X. Xia"'
Autor:
Tsuyomu Ikenoue, Michihiro Fujiwara, Katsunori Iwasaki, Tetsuya Yoshikawa, Kenichi Mishima, Yi X. Xia, Nobuaki Egashira, Naoya Aoo, Tomoaki Ikeda
Publikováno v:
Behavioural Brain Research. 151:209-217
We previously reported that rats exposed to neonatal hypoxic-ischemic (HI) insult showed selective and long-lasting learning and memory impairments in the plus maze, 8-arm radial maze, choice reaction time (CRT) task, and water maze, and that they sh
Autor:
Tsuyomu Ikenoue, Yi X. Xia, Katsunori Iwasaki, Michihiro Fujiwara, Kenichi Mishima, Tomoaki Ikeda, Tetsuya Yoshikawa
Publikováno v:
Behavioural Brain Research. 136:161-170
We examined for 18 weeks the effect of dexamethasone treatment on learning and memory impairment produced by hypoxic-ischemic stress at postnatal day 7 in rat in addition to brain histological study. Dexamethasone of 0.5 mg/kg was injected i.p. 4 h b
Publikováno v:
Neuroscience Letters. 329:33-36
The free radical scavenger 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), which has been approved in Japan for use in patients with cerebral infarction, was used to treat ischemic-hypoxic brain damage in neonatal rats. Seven-day-old rat pups were sub
Autor:
Yi X. Xia, Arturo Ota, Kiyotaka Toshimori, Tsuyomu Ikenoue, Xiao Y. Xia, Hiroshi Sameshima, Tomoaki Ikeda
Publikováno v:
American Journal of Obstetrics and Gynecology. 180:1254-1262
Objective: This study was intended to investigate the temporal changes in heat shock protein 72 expression and microtubule-associated protein 2 disappearance in rat brain at 2 different ages after hypoxic-ischemic insult. Study Design: Both 5-day-old
Autor:
Arturo Ota, Yi X. Xia, Hiroshi Sameshima, Tomoaki Ikeda, Tsuyomu Ikenoue, Xiao Y. Xia, Koji Abe
Publikováno v:
American Journal of Obstetrics and Gynecology. 179:1075-1078
Objective: Our purpose was to determine whether hypoxic-ischemic brain damage would be protected against by advance conditioning of the animal with 4 hours of hypoxic exposure. Study Design: Neonatal rats were exposed on postnatal day 7 to (1) 4 hour
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 20(7)
In order to delineate the spatial and temporal patterns of glial cell line-derived neurotrophic factor (GDNF) expression following ischemic/hypoxic injury in immature and neonatal brain, GDNF protein levels and immunocytochemistry were studied in rat
Selective and long-term learning impairment following neonatal hypoxic-ischemic brain insult in rats
Autor:
Yi X. Xia, Michihiro Fujiwara, Tetsuya Yoshikawa, Katsunori Iwasaki, Tsuyomu Ikenoue, Tomoaki Ikeda, Kenichi Mishima
Publikováno v:
Behavioural brain research. 118(1)
We examined four different learning and memory tasks in rats which had been subjected to left carotid artery ligation followed by 2 h hypoxia (8% oxygen) when they were 7 days old. The examination began on the 4th week after insult and continued to 1
Publikováno v:
Journal of the Society for Gynecologic Investigation. 7(2)
We investigated the effect of hyperthermic pretreatment 24 hours before hypoxic-ischemic exposure on neuronal cell damage in 7-day-old rats.Newborn rats were separated on postnatal day 7 into two groups: 1) preheated (those exposed to 2 hours of hype
Publikováno v:
American journal of obstetrics and gynecology. 182(2)
Objectives: Hypoxic-ischemic tolerance can be induced in neonatal rats through hyperthermic preconditioning. The purposes of this study were to determine the interval between hyperthermic preconditioning and a subsequent hypoxic-ischemic insult that
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 17(7)
Expression of GDNF in developing rat brain from PND 1 to 14 and on PND 21 was examined immunocytochemically. At PND 1, intense diffuse immunoreactivity was noted within the cytoplasm of a diverse group of neuronal and nonneuronal cells, including cho