Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yi Ting Koh"'
Autor:
Joel Crespo, Yi Ting Koh, Ningjie Hu, Paul A Moore, Ezio Bonvini, Andrew L Glasebrook, Andrea P Martin, Robert J Benschop
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245917 (2021)
Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how anti-human CD3 therapy works based on recent longitudinal studies of short-term administration. Altho
Externí odkaz:
https://doaj.org/article/284cea3843ea48808b3b32fa3cdf258b
Autor:
William A. Rose, Angela J. Okragly, Ningjie N. Hu, Montanea R. Daniels, Andrea P. Martin, Yi Ting Koh, Kristine Kikly, Robert J. Benschop
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Breaking tolerance is a key event leading to autoimmunity, but the exact mechanisms responsible for this remain uncertain. Here we show that the alarmin IL-33 is able to drive the generation of autoantibodies through induction of the B cell survival
Externí odkaz:
https://doaj.org/article/d1228f9ab1f94cada93acf6e5a47d8bd
Autor:
Sylvia Kam, Nirmal Kavalloor Visruthan, Jocelyn Y. X. Lim, Ai Ling Koh, Terrence Thomas, Natalie Yi Ting Koh, Jan Hau Lee
Publikováno v:
Annals of the Academy of Medicine, Singapore. 50(2)
Autor:
Yi Ting Koh, Andrew L. Glasebrook, Ningjie Hu, Ezio Bonvini, Joel Crespo, Andrea P. Martin, Robert J. Benschop, Paul A. Moore
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245917 (2021)
PLoS ONE
PLoS ONE
Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how anti-human CD3 therapy works based on recent longitudinal studies of short-term administration. Altho
Autor:
Ningjie N. Hu, William A. Rose, Yi Ting Koh, Kristine Kay Kikly, Angela J. Okragly, Montanea R. Daniels, Andrea P. Martin, Robert J. Benschop
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Breaking tolerance is a key event leading to autoimmunity, but the exact mechanisms responsible for this remain uncertain. Here we show that the alarmin IL-33 is able to drive the generation of autoantibodies through induction of the B cell survival
Autor:
Argyrios N. Theofilopoulos, Rosana Gonzalez-Quintial, Dwight H. Kono, Yi Ting Koh, Bruce Beutler, Roberto Baccala, Brian R. Lawson, Michael E. Stern
Publikováno v:
Nature Reviews Rheumatology. 6:146-156
Evidence strongly suggests that excessive or protracted signaling, or both, by cell-surface or intracellular innate immune receptors is central to the pathogenesis of most autoimmune and autoinflammatory rheumatic diseases. The initiation of aberrant
Publikováno v:
The Prostate. 69:571-584
BACKGROUND Androgen ablation (AA) causes apoptosis of normal and neoplastic prostate cells. It is a standard treatment for advanced prostate cancer. Androgen ablation-mediated immunological effects include bone marrow hyperplasia, thymic regeneration
Publikováno v:
Scientific Reports
Polydimethylsiloxane (PDMS) has been extensively exploited to study stem cell physiology in the field of mechanobiology and microfluidic chips due to their transparency, low cost and ease of fabrication. However, its intrinsic high hydrophobicity ren
Publikováno v:
Vaccine. 23:2639-2646
Immunization with naked plasmid DNA elicits strong cell-mediated immune responses. In the present study, we examine strategies to enhance epitope-specific cytotoxic T lymphocyte (CTL) responses using DNA constructs, expressing a minimal class I epito
Autor:
Bruce Beutler, K. Michael Pollard, John C. Scatizzi, Dwight H. Kono, Argyrios N. Theofilopoulos, Brian R. Lawson, Roberto Baccala, Jennifer D. Gahan, Yi Ting Koh
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(10)
Nucleic acid (NA)–sensing TLRs (NA-TLRs) promote the induction of anti-nuclear Abs in systemic lupus erythematosus. However, the extent to which other nonnuclear pathogenic autoantibody specificities that occur in lupus and independently in other a