Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yi Tian Ting"'
Autor:
Peter J. Eggenhuizen, Rachel M. Y. Cheong, Cecilia Lo, Janet Chang, Boaz H. Ng, Yi Tian Ting, Julie A. Monk, Khai L. Loh, Ashraf Broury, Elean S. V. Tay, Chanjuan Shen, Yong Zhong, Steven Lim, Jia Xi Chung, Rangi Kandane-Rathnayake, Rachel Koelmeyer, Alberta Hoi, Ashutosh Chaudhry, Paolo Manzanillo, Sarah L. Snelgrove, Eric F. Morand, Joshua D. Ooi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Antigen-specific regulatory T cells (Tregs) suppress pathogenic autoreactivity and are potential therapeutic candidates for autoimmune diseases such as systemic lupus erythematosus (SLE). Lupus nephritis is associated with autoreactivity to
Externí odkaz:
https://doaj.org/article/8948013d714c4e8e98c3470282119cef
Autor:
Haniyeh Aghababa, Yi Tian Ting, Devaki Pilapitiya, Jacelyn M.S. Loh, Paul G. Young, Thomas Proft
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 225-240 (2022)
Streptococcus pyogenes, a leading human pathogen, is responsible for a wide range of diseases, including skin and soft tissue infections and severe invasive diseases. S. pyogenes produces a large arsenal of virulence factors, including several immune
Externí odkaz:
https://doaj.org/article/9ba5dab223574f529bcd0c7819a75fbf
Autor:
Mai T. Tran, Pouya Faridi, Jia Jia Lim, Yi Tian Ting, Goodluck Onwukwe, Pushpak Bhattacharjee, Claerwen M. Jones, Eleonora Tresoldi, Fergus J. Cameron, Nicole L. La Gruta, Anthony W. Purcell, Stuart I. Mannering, Jamie Rossjohn, Hugh H. Reid
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Epitopes formed by fusion of more than one self peptide, such as proinsulin and other β cell proteins, can result in the formation of non-self hybrid peptides that can potentially trigger autoimmune responses. Here the authors show how TRBV5 + T cel
Externí odkaz:
https://doaj.org/article/6cfc61766a5b4c9d973ece4ad2e9ab57
Autor:
Peter J. Eggenhuizen, Boaz H. Ng, Janet Chang, Rachel M.Y. Cheong, Anusha Yellapragada, Wey Y. Wong, Yi Tian Ting, Julie A. Monk, Poh-Yi Gan, Stephen R. Holdsworth, Joshua D. Ooi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Heterologous immunity, when the memory T cell response elicited by one pathogen recognizes another pathogen, has been offered as a contributing factor for the high variability in coronavirus disease 2019 (COVID-19) severity outcomes. Here we demonstr
Externí odkaz:
https://doaj.org/article/f33870b382f64739b74e931f64392c17
Autor:
Yi Tian Ting, Paul W. R. Harris, Gaelle Batot, Margaret A. Brimble, Edward N. Baker, Paul G. Young
Publikováno v:
IUCrJ, Vol 3, Iss 1, Pp 10-19 (2016)
Bacterial type I signal peptidases (SPases) are membrane-anchored serine proteases that process the signal peptides of proteins exported via the Sec and Tat secretion systems. Despite their crucial importance for bacterial virulence and their attract
Externí odkaz:
https://doaj.org/article/89787dd770a949b9b59d2d376c2965eb
Autor:
Ries J Langley, Yi Tian Ting, Fiona Clow, Paul G Young, Fiona J Radcliff, Jeong Min Choi, Richard P Sequeira, Silva Holtfreter, Heather Baker, John D Fraser
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006549 (2017)
Staphylococcus aureus is an opportunistic pathogen that produces many virulence factors. Two major families of which are the staphylococcal superantigens (SAgs) and the Staphylococcal Superantigen-Like (SSL) exoproteins. The former are immunomodulato
Externí odkaz:
https://doaj.org/article/40b9902d97ac42128986edcdb616c876
Autor:
Aghababa, Haniyeh1, Yi Tian Ting2,3, Pilapitiya, Devaki1,4, Loh, Jacelyn M. S.1,5, Young, Paul G.2,5 p.young@auckland.ac.nz, Proft, Thomas1,5 t.proft@auckland.ac.nz
Publikováno v:
Virulence. Dec2022, Vol. 13 Issue 1, p225-240. 16p.
Autor:
Joshua Ooi, Rachel Cheong, Peter Eggenhuizen, Janet Chang, Ashraf Broury, Boaz Ng, Khai Loh, Elean Tay, Chanjuan Shen, Julie Monk, Yong Zhong, Steven Lim, Jia Xi Chung, Rangi Kandane-Rathnayake, Rachel Koelmeyer, Alberta Hoi, Ashutosh Chaudhry, Sarah Snelgrove, Yi Tian Ting, Eric Morand
Antigen-specific regulatory T cells (Tregs) suppress pathogenic autoreactivity and are potential therapeutic candidates for autoimmune diseases such as systemic lupus erythematosus (SLE). Lupus nephritis is associated with autoreactivity to the Smith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c23e569baa19cc5b0782896c277ceed
https://doi.org/10.21203/rs.3.rs-2663329/v1
https://doi.org/10.21203/rs.3.rs-2663329/v1
Autor:
Goodluck Onwukwe, Mai T. Tran, Jamie Rossjohn, Jia Jia Lim, Eleonora Tresoldi, Nicole L. La Gruta, Claerwen M. Jones, Pouya Faridi, Pushpak Bhattacharjee, Anthony W. Purcell, Fergus J. Cameron, Hugh H. Reid, Yi Tian Ting, Stuart I. Mannering
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
HLA-DQ8, a genetic risk factor in type I diabetes (T1D), presents hybrid insulin peptides (HIPs) to autoreactive CD4+ T cells. The abundance of spliced peptides binding to HLA-DQ8 and how they are subsequently recognised by the autoreactive T cell re
Autor:
Murray McKinnon, Nathan J. Felix, Nicole L. La Gruta, Claerwen M. Jones, Vivianne Malmström, Jia Jia Lim, Anthony W. Purcell, Jamie Rossjohn, Tiing Jen Loh, Yi Tian Ting, Daniel Baker, Pirooz Zareie, Lars Klareskog, Khai Lee Loh, Frederik Stevenaert, Anish Suri, Ravi Sharma, Hugh H. Reid
Publikováno v:
Science Immunology. 6
Individuals expressing HLA-DR4 bearing the shared susceptibility epitope (SE) have an increased risk of developing rheumatoid arthritis (RA). Posttranslational modification of self-proteins via citrullination leads to the formation of neoantigens tha