Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yi Seok, Chang"'
Autor:
Leah Stein, Karthikeyan Murugesan, Julie W. Reeser, Zachary Risch, Michele R. Wing, Anoosha Paruchuri, Eric Samorodnitsky, Emily L. Hoskins, Thuy Dao, Amy Smith, Dat Le, Melissa A. Babcook, Yi Seok Chang, Matthew R. Avenarius, Muhammad Imam, Aharon G. Freud, Sameek Roychowdhury
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Genomic alterations in fibroblast growth factor receptor (FGFR) genes are present in a small number of metastatic pancreatic ductal adenocarcinomas (PDAC) and may represent an emerging subgroup of patients likely to benefit from FGFR targete
Externí odkaz:
https://doaj.org/article/a41e0b6fdf164294aff1b7579f669da5
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Active surveillance (AS) can be considered as an alternative to immediate surgery in low-risk papillary thyroid microcarcinoma (PTMC) without clinically apparent lymph nodes, gross extrathyroidal extension (ETE), and/or distant metastasis according t
Externí odkaz:
https://doaj.org/article/11e528a54a304bd086dd1ed27b9ccd1c
Autor:
Brynn Hollingsworth, Jennifer A. Sipos, Luke K Genutis, Yi Seok Chang, Christopher J. Walker, Pamela Brock, Electron Kebebew, Patience Green, Fadi Nabhan, W. G. Li, Sandya Liyanarachchi, Gilbert J. Cote, Steven I. Sherman, Sissy M. Jhiang, Albert de la Chapelle, Shuai Xue, Zachary A. Hurst, Huiling He, Eric Menq
Publikováno v:
Thyroid. 29:530-539
Background: Thyroid cancer patients with radioiodine-refractory (RAI-R) disease, resulting from insufficient RAI delivery and/or RAI resistance, have increased mortality and limited treatment options. To date, studies have largely focused on tumor mu
Publikováno v:
Cancer Research. 78:6121-6133
The sodium iodide symporter (NIS) is a classical iodide pump typically localized within the cell plasma membrane in thyroid cells, where NIS expression is believed to ensure success of mainstay radioiodide therapy in thyroid cancers. Although radioio
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Frontiers in Endocrinology
Frontiers in Endocrinology
Active surveillance (AS) can be considered as an alternative to immediate surgery in low-risk papillary thyroid microcarcinoma (PTMC) without clinically apparent lymph nodes, gross extrathyroidal extension (ETE), and/or distant metastasis according t
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(34)
Chemotherapy is a double-edged sword. It is anticancer because of its cytotoxicity. Paradoxically, by increasing chemoresistance and cancer metastasis, it is also procancer. However, the underlying mechanisms for chemotherapy-induced procancer activi
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Chemotherapy is a double-edged sword. It is anticancer because of its cytotoxicity. Paradoxically, by increasing chemoresistance and cancer metastasis, it is also procancer. However, the underlying mechanisms for chemotherapy-induced procancer activi
Autor:
Ewan K.A. Millar, Erik Zmuda, Michael C. Ostrowski, Swati P. Jalgaonkar, Stephen J. McConoughey, Chris C. Wolford, Stephanie L. Roller, Marino E. Leon, Yi-Seok Chang, Robert L. Sutherland, Anand S. Merchant, Tsonwin Hai, Charles L. Shapiro, Sandra A O'Toole, Johnna L. Dominick, Xin Yin
Publikováno v:
Journal of Clinical Investigation. 123:2893-2906
Host response to cancer signals has emerged as a key factor in cancer development; however, the underlying molecular mechanism is not well understood. In this report, we demonstrate that activating transcription factor 3 (ATF3), a hub of the cellular
Autor:
Tsonwin Hai, Alan Aderem, Yi-Seok Chang, Stephen A. Ramsey, Stephen J. McConoughey, Xin Yin, Christopher C. Wolford
Publikováno v:
Journal of Cell Science. 123:3558-3565
The activating transcription factor 3 (ATF3) gene is induced by a variety of signals, including many of those encountered by cancer cells. We present evidence that ATF3 is induced by TGFβ in the MCF10CA1a breast cancer cells and plays an integral ro
Publikováno v:
Gene Expression. 15:1-11
Activating transcription factor 3 (ATF3) gene encodes a member of the ATF family of transcription factors and is induced by various stress signals. All members of this family share the basic region-leucine zipper (bZip) DNA binding motif and bind to