Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Yi Ru Pan"'
Autor:
Chiao-Ping Chen, Tsai-Hsien Hung, Ping-Chih Hsu, Chun-Nan Yeh, Wen-Kuan Huang, Yi-Ru Pan, Yu-Tien Hsiao, Chih-Hong Lo, Chiao-En Wu
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40299- (2024)
Background: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality. Chemotherapy is crucial in NSCLC treatment, and targeting Wee1 kinase, a key regulator of the G2/M cell cycle checkpoint, may enhance the efficacy of
Externí odkaz:
https://doaj.org/article/f4213b2038d249e2b86209cfa475d6af
Autor:
Chiao-Ping Chen, Shu-Fu Lin, Chun-Nan Yeh, Wen-Kuan Huang, Yi-Ru Pan, Yu-Tien Hsiao, Chih-Hong Lo, Chiao-En Wu
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29055- (2024)
Background: Anaplastic thyroid cancer (ATC), a rare and aggressive malignancy with a poor prognosis, has shown promise with the approved dabrafenib/trametinib combination for BRAFV600E mutation. Co-occurring PI3KCA mutations, identified as negative p
Externí odkaz:
https://doaj.org/article/ed076d5ed71b4007a7754c1b3c015f77
Autor:
Chiao-Ping Chen, Chun-Nan Yeh, Yi-Ru Pan, Wen-Kuan Huang, Yu-Tien Hsiao, Chih-Hong Lo, Chiao-En Wu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115389- (2023)
Patients with advanced biliary tract cancer (BTC) have a poor prognosis, and novel treatments are needed. Gemcitabine, the standard of care for BTC, induces DNA damage; however, the ability of cancer cells to repair DNA dampens its effects. To improv
Externí odkaz:
https://doaj.org/article/28151b94a1054d259facfdc9571eff83
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Antimicrobial peptides are important components of the host innate immune system, forming the first line of defense against infectious microorganisms. Among them, liver-expressed antimicrobial peptides (LEAPs) are a family of antimicrobial peptides t
Externí odkaz:
https://doaj.org/article/3689dc35d3a14b5eb65ed6d4fbfb844a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cholangiocarcinoma (CCA) is the second most common primary liver malignancy and carries a dismal prognosis due to difficulties in achieving an optimal resection, and poor response to current standard-of-care systemic therapies. We previously devised
Externí odkaz:
https://doaj.org/article/8cb5f1dfc98441fca69497dde575bc5a
Autor:
Chiao-En Wu, Chiao-Ping Chen, Wen-Kuan Huang, Yi-Ru Pan, Erhan Aptullahoglu, Chun-Nan Yeh, John Lunec
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
KIT and PDGFRA play a major role in the oncogenic process in gastrointestinal stroma tumors (GIST) and small molecules have been employed with great success to target the KIT and PDGFRA pathways in this cancer. However, approximately 10% of patients
Externí odkaz:
https://doaj.org/article/72f0d93c72be43c786986b48217fa31c
Autor:
Yi‐Ru Pan, Chiao‐En Wu, Yu‐Chao Wang, Yi‐Chen Yeh, Meng‐Lun Lu, Yi‐Ping Hung, Yee Chao, Da‐Wei Yeh, Chien‐Hsing Lin, Jason Chia‐Hsun Hsieh, Ming‐Huang Chen, Chun‐Nan Yeh
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Objective Immune checkpoint inhibitors (ICIs) have become the standard of care in various cancers, although the predictive tool is still unknown. Methods This study aimed to develop a novel gene panel by selecting DNA damage response (DDR) g
Externí odkaz:
https://doaj.org/article/32eaf414769d41edbd652067a66e7adf
Autor:
Yi-Ru Pan, Chih-Cheng Chen, Yu-Tien Chan, Hsiao-Jung Wang, Fan-Tso Chien, Yeng-Long Chen, Jing-Lan Liu, Muh-Hwa Yang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The mechanism underlying the dissemination of diffuse large B-cell lymphoma (DLBCL) is unclear. Here, the authors show that STAT3 controls amoeboid migration in DLBCL via the transcriptional activation of RHOH, which then releases RhoA from RhoGDIγ-
Externí odkaz:
https://doaj.org/article/95f73b88a6d342eb9cd45626c936f80a
Autor:
Shin-Yi Chung, Yi-Ping Hung, Yi-Ru Pan, Yu-Chan Chang, Chiao-En Wu, Dennis Shin-Shian Hsu, Peter Mu-Hsin Chang, Meng-Lun Lu, Chi-Ying F. Huang, Yeu Su, Michael Hsiao, Chun-Nan Yeh, Ming-Huang Chen
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 885 (2021)
Cholangiocarcinoma is the most common primary malignant tumor of the bile duct. The current standard first-line treatment for advanced or metastatic cholangiocarcinoma is gemcitabine and cisplatin. However, few effective treatment choices exist for r
Externí odkaz:
https://doaj.org/article/6e5f453b2e3b47deae6f73e1420b860b
Autor:
Chun-Nan Yeh, Wen-Kuan Huang, Chun-Wei Lu, Chiao-Ping Chen, Sheng-Hsuan Lin, Yi-Ru Pan, Chiao-En Wu
Publikováno v:
Biological Trace Element Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b3cf14d08d23dabd841288eeaaacaf
https://doi.org/10.1007/s12011-023-03618-y
https://doi.org/10.1007/s12011-023-03618-y