Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yi Peter Hu"'
Autor:
Xun Meng, Wenhao Hu, Shu-Hui Liu, Yu Qian, Guoqiang Hua, Yi Peter Hu, Jianjian Zhang, Junyi Pu, Hui Zhang, Biao Zhou, Lijun Wang, Caiwei Chen, Linjie Ma, Rong Pan, Mingqiao Wang, Zhaohui Wang, Yue Zhang, Jing Shi, Guoxiang Fu, Yi Shen, Qianqian Zhao, Tao Meng, Weining Weng
Supplementary Figure S1 shows Exatecan cytotoxicity and sensitivity to multidrug resistant genes. Supplementary Figure S2 shows Exatecan and DXd/SN-38 sensitivity to multidrug resistant genes. Supplementary Figure S3 shows Exatecan toxicity in rat. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ce6bdaea1330850b6fd2c3b851fe07
https://doi.org/10.1158/2159-8290.22553455.v1
https://doi.org/10.1158/2159-8290.22553455.v1
Autor:
Xun Meng, Wenhao Hu, Shu-Hui Liu, Yu Qian, Guoqiang Hua, Yi Peter Hu, Jianjian Zhang, Junyi Pu, Hui Zhang, Biao Zhou, Lijun Wang, Caiwei Chen, Linjie Ma, Rong Pan, Mingqiao Wang, Zhaohui Wang, Yue Zhang, Jing Shi, Guoxiang Fu, Yi Shen, Qianqian Zhao, Tao Meng, Weining Weng
Supplementary note shows the analytical characterization of the ADCs, and synthesis of drug-linkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21bfe40e4106b1e91b818c166ebebc5f
https://doi.org/10.1158/2159-8290.22553452
https://doi.org/10.1158/2159-8290.22553452
Autor:
Xun Meng, Wenhao Hu, Shu-Hui Liu, Yu Qian, Guoqiang Hua, Yi Peter Hu, Jianjian Zhang, Junyi Pu, Hui Zhang, Biao Zhou, Lijun Wang, Caiwei Chen, Linjie Ma, Rong Pan, Mingqiao Wang, Zhaohui Wang, Yue Zhang, Jing Shi, Guoxiang Fu, Yi Shen, Qianqian Zhao, Tao Meng, Weining Weng
Supplementary Table S1 shows cytotoxicity of exatecan compared to DXd. Supplementary Table S2 shows selected hematologic parameters and biochemical parameters from the repeat-dose administration of exatecan mesylate studies in rats. Supplementary Tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c3030dcc4f49fa87088a68b94ff786
https://doi.org/10.1158/2159-8290.22553449.v1
https://doi.org/10.1158/2159-8290.22553449.v1
Autor:
Xun Meng, Wenhao Hu, Shu-Hui Liu, Yu Qian, Guoqiang Hua, Yi Peter Hu, Jianjian Zhang, Junyi Pu, Hui Zhang, Biao Zhou, Lijun Wang, Caiwei Chen, Linjie Ma, Rong Pan, Mingqiao Wang, Zhaohui Wang, Yue Zhang, Jing Shi, Guoxiang Fu, Yi Shen, Qianqian Zhao, Tao Meng, Weining Weng
Antibody–drug conjugates (ADC) using DNA topoisomerase I inhibitor DXd/SN-38 have transformed cancer treatment, yet more effective ADCs are needed for overcoming resistance. We have designed an ADC class using a novel self-immolative T moiety for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1001d2baf053a41af37a7c38feee09
https://doi.org/10.1158/2159-8290.c.6534720.v1
https://doi.org/10.1158/2159-8290.c.6534720.v1
Autor:
Lisa E. Humphrey, Jennie Hauser, Wenhui Li, Michael G. Brattain, Sandip B. Patil, Michelle Panasiewicz, Yi Peter Hu
Publikováno v:
Cancer Research. 68:8004-8013
This study identifies a novel cross-talk paradigm between the type I insulin-like growth factor receptor (IGF1R) and epidermal growth factor receptor (EGFR) in colon cancer cells. IGF1R activation by ligand exposure in growth factor–deprived cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3562957e5da6a7ca7924de2d4deb0147
https://doi.org/10.1158/0008-5472.can-08-0280
https://doi.org/10.1158/0008-5472.can-08-0280
Autor:
Jennie Hauser, Lisa E. Humphrey, Srinivas Venkateswarlu, Elizabeth Zborowska, Wenhui Li, Michael G. Brattain, Gillian M. Howell, James K V Willson, Patricia J. St. Clair, Yi Peter Hu, Natalia Sergina
Publikováno v:
Journal of Biological Chemistry. 280:27383-27392
The role of the ErbB family in supporting the malignant phenotype was characterized by stable transfection of a single chain antibody (ScFv5R) against ErbB2 containing a KDEL endoplasmic reticulum retention sequence into GEO human colon carcinoma cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e35d7c6cc109a6c8c51e9b19e52cb4
https://doi.org/10.1074/jbc.m414238200
https://doi.org/10.1074/jbc.m414238200
Autor:
Yi Peter Hu1,2, Venkateswarlud, Srinivas3, Serginall, Natalia3, Howell, Gillian1, St. Clair, Patricia3, Humphrey, Lisa E.1, Wenhui Li3, Hauser, Jennie1, Zborowska, Elizabeth4, Willson, James K. V.4, Brattain, Michael G.1 Michael.brattain@roswellpark.org
Publikováno v:
Journal of Biological Chemistry. 7/22/2005, Vol. 280 Issue 29, p27383-27392. 10p. 27 Graphs.
Autor:
Dominguez, Ivan1, Yi, Peter Hu2, Sharratt, Elizabeth3, Howell, Gillian2, Spernyak, Joseph3, Wang, Jing2, Brattain, Michael2, Rajput, Ashwani3
Publikováno v:
Journal of Surgical Research. Feb2008, Vol. 144 Issue 2, p222-223. 2p.