Zobrazeno 1 - 10
of 4 853
pro vyhledávání: '"Yi PAN"'
Autor:
Tianci Kong, Tiancheng Yu, Jiaxin Zhao, Zhenhua Hu, Neal Xiong, Jian Wan, Xiaoliang Dong, Yi Pan, Huilin Zheng, Lei Zhang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Single-cell RNA sequencing (scRNA-seq) is a key technology for investigating cell development and analysing cell diversity across various diseases. However, the high dimensionality and extreme sparsity of scRNA-seq data pose great challenges
Externí odkaz:
https://doaj.org/article/dd205984395948c1a7ea6ef443b21940
Publikováno v:
Big Data Mining and Analytics, Vol 7, Iss 3, Pp 828-842 (2024)
Accurately diagnosing Alzheimer’s disease is essential for improving elderly health. Meanwhile, accurate prediction of the mini-mental state examination score also can measure cognition impairment and track the progression of Alzheimer’s disease.
Externí odkaz:
https://doaj.org/article/2ffa80bb3a8243c49ce8ea7b9e67c65d
Publikováno v:
Big Data Mining and Analytics, Vol 7, Iss 3, Pp 781-793 (2024)
Autism Spectrum Disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the machine learni
Externí odkaz:
https://doaj.org/article/f6b9248fc5f34a758e6154165052503c
Autor:
Shan Liang, Zongbiao Duan, Xuemei He, Xia Yang, Yaqin Yuan, Qianjin Liang, Yi Pan, Guoan Zhou, Min Zhang, Shulin Liu, Zhixi Tian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Seed size/weight plays an important role in determining crop yield, yet only few genes controlling seed size have been characterized in soybean. Here, we perform a genome-wide association study and identify a major quantitative trait locus (
Externí odkaz:
https://doaj.org/article/86558fe2e26a43b2aa796dcee9d3a22b
Autor:
Tianshi Mao, Jie Chen, Tong Su, Long Xie, Xinyan Qu, Ruli Feng, Yi Pan, Jie Wan, Xiaoyun Cui, Wenhao Jia, Qun Gao, Qian Lin
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Glucagon-like peptide-1 receptor (GLP1R) agonists have been shown to reduce major cardiovascular events in diabetic patients, but their role in heart failure (HF) remains controversial. Recent evidence implies their potential bene
Externí odkaz:
https://doaj.org/article/ddf9bd0d96194944bd33b060d1371099
Autor:
Jia Xu, Yilin Liu, Qing Wang, Xiangzhang Tao, Shengyang Ni, Weigang Zhang, Lei Yu, Yi Pan, Yi Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Alkylamine structures represent one of the most functional and widely used in organic synthesis and drug design. However, the general methods for the functionalization of the shielded and deshielded alkyl radicals remain elusive. Here, we re
Externí odkaz:
https://doaj.org/article/a353595d512c4c43a470c47d5e0e3891
Autor:
Li-Min Lei, Fu-Xing-Zi Li, Xiao Lin, Feng Xu, Su-Kang Shan, Bei Guo, Ming-Hui Zheng, Ke-Xin Tang, Yi Wang, Qiu-Shuang Xu, Wen-Lu Ouyang, Jia-Yue Duan, Yun-Yun Wu, Ye-Chi Cao, Zhi-Ang Zhou, Si-Yang He, Yan-Lin Wu, Xi Chen, Zheng-Jun Lin, Yi Pan, Ling-Qing Yuan, Zhi-Hong Li
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Recently, environmental temperature has been shown to regulate bone homeostasis. However, the mechanisms by which cold exposure affects bone mass remain unclear. In our present study, we observed that exposure to cold temperature (CT) decrea
Externí odkaz:
https://doaj.org/article/3b2ab9d30b6147afb6c8b61824265322
Autor:
Mini Han Wang, Lumin Xing, Yi Pan, Feng Gu, Junbin Fang, Xiangrong Yu, Chi Pui Pang, Kelvin Kam-Lung Chong, Carol Yim-Lui Cheung, Xulin Liao, Xiaoxiao Fang, Jie Yang, Ruoyu Zhou, Xiaoshu Zhou, Fengling Wang, Wenjian Liu
Publikováno v:
Big Data Mining and Analytics, Vol 7, Iss 2, Pp 445-484 (2024)
This study explores the potential of Artificial Intelligence (AI) in early screening and prognosis of Dry Eye Disease (DED), aiming to enhance the accuracy of therapeutic approaches for eye-care practitioners. Despite the promising opportunities, cha
Externí odkaz:
https://doaj.org/article/b81d8db3ceab44448e3301eeef2ce200
Autor:
Shene Chiou, Aysha H Al-Ani, Yi Pan, Komal M Patel, Isabella Y Kong, Lachlan W Whitehead, Amanda Light, Samuel N Young, Marilou Barrios, Callum Sargeant, Pradeep Rajasekhar, Leah Zhu, Anne Hempel, Ann Lin, James A Rickard, Cathrine Hall, Pradnya Gangatirkar, Raymond KH Yip, Wayne Cawthorne, Annette V Jacobsen, Christopher R Horne, Katherine R Martin, Lisa J Ioannidis, Diana S Hansen, Jessica Day, Ian P Wicks, Charity Law, Matthew E Ritchie, Rory Bowden, Joanne M Hildebrand, Lorraine A O’Reilly, John Silke, Lisa Giulino-Roth, Ellen Tsui, Kelly L Rogers, Edwin D Hawkins, Britt Christensen, James M Murphy, André L Samson
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1717-1749 (2024)
Abstract Necroptosis is a lytic form of regulated cell death reported to contribute to inflammatory diseases of the gut, skin and lung, as well as ischemic-reperfusion injuries of the kidney, heart and brain. However, precise identification of the ce
Externí odkaz:
https://doaj.org/article/3261c59629e24716b5f237cbc3d2531c
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 3, Pp 354-372 (2024)
Glucagon-like peptide-1 (GLP-1) is a 30-amino acid peptide hormone that is mainly expressed in the intestine and hypothalamus. In recent years, basic and clinical studies have shown that GLP-1 is closely related to lipid metabolism, and it can partic
Externí odkaz:
https://doaj.org/article/809df444cc3e4f27b7f16085267e3d93