Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yi Meen Chou"'
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(18):2643-2646
Publikováno v:
Journal of the Chinese Chemical Society. 46:601-605
The reaction of mercaptoacetaldehyde dialkyl acetals 1a-c in the presence of sulfuric acid, polyphosphoric acid and zinc chloride is described. Other than the disulfide reported previously, new compounds 1,2-bis-(mercapto)ethylene, 1,2,3-tris-(mercap
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:607-610
The prototype biselectrostatic chain, 6-(hydroxymethyl)-2,11-diamino-5,8-dithiaundecane linked to the 4-phenylphenol, 3-phenylphenol and 2-phenyl-4-quinoline derivatives bind strongly to double helical DNA with binding constants of 1.5 × 105, 3.9 ×
Publikováno v:
ChemInform. 28
The base alkylation of 2,3-dimercapto-1-propanol with alkyl halides leads in good yield to 2,3-bis(alkylthio)-1-propanol and dialkyl sulfide. The reaction of 2,3-bis(alkylthio)-1-propanol with catalytic concentrated sulfuric acid proceeds with rearra
Publikováno v:
ChemInform. 30
A series of bithienyl-pyrimidines having cationic side chain have been developed as antitumor agents. This work illustrates the overwhelming importance of the bithienyl unit for efficient DNA binding. The X-ray structure of 4-(2′,2″-thien-5-yl)-2
Publikováno v:
Journal of the Chinese Chemical Society. 43:73-75
The HAPP-Fe complex was more active than HAPP-Cu complex in cleavage of DNA in the presence of dithiothreitol and hydrogen peroxide. In contrast, the HAPP-Cu complex was found to bind more strongly with λ-DNA, whereas the HAPP-Fe binds weakly. It wa
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(18)
A series of bithienyl-pyrimidines having cationic side chain have been developed as antitumor agents. This work illustrates the overwhelming importance of the bithienyl unit for efficient DNA binding. The X-ray structure of 4-(2′,2″-thien-5-yl)-2
Publikováno v:
The Journal of organic chemistry. 61(23)
The base alkylation of 2,3-dimercapto-1-propanol with alkyl halides leads in good yield to 2,3-bis(alkylthio)-1-propanol and dialkyl sulfide. The reaction of 2,3-bis(alkylthio)-1-propanol with catalytic concentrated sulfuric acid proceeds with rearra