Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yi Ling Goh"'
Autor:
GuangRong Peh, Terence Tay, Lee Ling Tan, Elaine Tiong, Jiawu Bi, Yi Ling Goh, Suming Ye, Fu Lin, Cheryl Jia Xin Tan, Yong Zi Tan, Joel Wong, Huimin Zhao, Fong Tian Wong, Ee Lui Ang, Yee Hwee Lim
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Halogenation of pyrrole requires strong electrophilic reagents and often leads to undesired polyhalogenated products. Biocatalytic halogenation is a highly attractive approach given its chemoselectivity and benign reaction conditions. While
Externí odkaz:
https://doaj.org/article/32c428dbb39e42669bd32c18f1dff135
Autor:
GuangRong Peh, Gregory A. Gunawan, Terence Tay, Elaine Tiong, Lee Ling Tan, Shimin Jiang, Yi Ling Goh, Suming Ye, Joel Wong, Christopher J. Brown, Huimin Zhao, Ee Lui Ang, Fong Tian Wong, Yee Hwee Lim
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1081 (2023)
RadH is one of the flavin-dependent halogenases that has previously exhibited promising catalytic activity towards hydroxycoumarin, hydroxyisoquinoline, and phenolic derivatives. Here, we evaluated new functional homologs of RadH and expanded its spe
Externí odkaz:
https://doaj.org/article/685de206982d4cb3b414fc26b0efd08c
Autor:
Lim, GuangRong Peh, Gregory A. Gunawan, Terence Tay, Elaine Tiong, Lee Ling Tan, Shimin Jiang, Yi Ling Goh, Suming Ye, Joel Wong, Christopher J. Brown, Huimin Zhao, Ee Lui Ang, Fong Tian Wong, Yee Hwee
Publikováno v:
Biomolecules; Volume 13; Issue 7; Pages: 1081
RadH is one of the flavin-dependent halogenases that has previously exhibited promising catalytic activity towards hydroxycoumarin, hydroxyisoquinoline, and phenolic derivatives. Here, we evaluated new functional homologs of RadH and expanded its spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ac6b66714e7ac42b592dbb8ae0aa4557
Autor:
Guangrong Peh, Terence Tay, Lee Ling Tan, Elaine Tiong, Yi Ling Goh, Suming Ye, Fu Lin, Cheryl Jia Xin Tan, Yong Zi Tan, Joel Wong, Huimin Zhao, Fong Tian Wong, Ee Lui Ang, Yee Hwee Lim
Halogenation of pyrrole requires strong electrophilic reagents and often leads to undesired polyhalogenated products. Biocatalytic halogenation is a highly attractive approach given its chemoselectivity and benign reaction conditions. Whilst there ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0356a8693e87a5a7d6d79f28a75fa1
https://doi.org/10.26434/chemrxiv-2022-t1mrn
https://doi.org/10.26434/chemrxiv-2022-t1mrn
Publikováno v:
ACS Medicinal Chemistry Letters. 8:516-520
Over the last few decades, resveratrol has gained significance due to its impressive array of biological activities; however, its true potential as a drug has been severely constrained by its poor bioavailability. Indeed, several studies have implica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30360d57d1cbcb4dbaaf3bf411d6246
https://doi.org/10.1021/acsmedchemlett.7b00018
https://doi.org/10.1021/acsmedchemlett.7b00018
Autor:
Eileen Yi Ling Goh, Yan Liu, Christina Jia Ying Chu, Jie Chang, Armando Borgna, Chuandayani Gunawan Gwie, Dapeng Liu
Publikováno v:
Applied Catalysis A: General. 523:118-129
The catalytic performance of ZSM-11 zeolites was studied in ethanol conversion to produce light olefins and BTX. Compared to HZSM-5 with same SiO2/Al2O3 ratio, it was found that HZSM-11 possesses significant advantages, resulting in higher stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f4d9bce9fa62ed1df3b51236d280e8
https://doi.org/10.1016/j.apcata.2016.05.030
https://doi.org/10.1016/j.apcata.2016.05.030
Autor:
Vikrant A. Adsool, Yi Ling Goh
Publikováno v:
Organic & Biomolecular Chemistry. 13:11597-11601
Exploration of novel chemical space, a modern trend in medicinal chemistry, is heavily reliant on synthetic access to new and interesting building blocks. In this direction, the following work describes an expedient synthesis of one such moiety, 3-fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ab9840981f36fc4946dda6f4e6fe4a
https://doi.org/10.1039/c5ob02066b
https://doi.org/10.1039/c5ob02066b
Autor:
Sridhar Santhanakrishnan, Tiong Wei Tan, Eric Tam, Zhimei Li, Sze Yue Wong, Cheryl Zi Hui Lim, Yi Ling Goh, Christina L. L. Chai, Tuan Minh Nguyen, Esther H. Q. Ong, Jeffrey Hill, Qiang Yu, Haiyan Yang, Xia Jiang, Puay Leng Lee
Publikováno v:
ChemMedChem. 10:173-182
3-Deazaneplanocin A (DzNep) is a potential epigenetic drug for the treatment of various cancers. DzNep has been reported to deplete histone methylations, including oncogenic EZH2 complex, giving rise to epigenetic modifications that reactivate many s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d79c60c92330be31558cb330b5a6c1
https://doi.org/10.1002/cmdc.201402315
https://doi.org/10.1002/cmdc.201402315
Autor:
Sridhar Santhanakrishnan, Yi Ling Goh, Zhengqiu Li, Eric Tam, Sze Yue Wong, Shao Q. Yao, Xiamin Cheng, Christina L. L. Chai
Publikováno v:
Chemistry - An Asian Journal. 8:1818-1828
3-Deazaneplanocin A (DzNep), a global histone methylation inhibitor, has attracted significant interest in epigenetic research in recent years. The molecular mechanism of action and the cellular off-targets of DzNep, however, are still not well-under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ffd3dfa101199e318f402f28058fb9
https://doi.org/10.1002/asia.201300303
https://doi.org/10.1002/asia.201300303
Autor:
Eric Tam, Choon Boon Cheong, Vikrant A. Adsool, Yi Ling Goh, Paul H. Bernardo, Anthony D. William, Charles W. Johannes
Publikováno v:
ChemInform. 45
A novel one-pot two-step approach allows the conversion of iodo substituted azide (I) into the target amine (II) on multigram scale.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c6e59d567dfcea442f8cc79f44af89f
https://doi.org/10.1002/chin.201437069
https://doi.org/10.1002/chin.201437069