Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Yi Hsin Hsu"'
Autor:
Heng-Huan Lee, Ying-Nai Wang, Wen-Hao Yang, Weiya Xia, Yongkun Wei, Li-Chuan Chan, Yu-Han Wang, Zhou Jiang, Shouping Xu, Jun Yao, Yufan Qiu, Yi-Hsin Hsu, Wei-Lun Hwang, Meisi Yan, Jong-Ho Cha, Jennifer L. Hsu, Jia Shen, Yuanqing Ye, Xifeng Wu, Ming-Feng Hou, Lin-Ming Tseng, Shao-Chun Wang, Mei-Ren Pan, Chin-Hua Yang, Yuan-Liang Wang, Hirohito Yamaguchi, Da Pang, Gabriel N. Hortobagyi, Dihua Yu, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Human ribonuclease 1 (hRNase 1) regulates innate immunity, hemostasis and RNA clearance. Here, the authors report an alternative function of hRNase 1 as a secretory ligand of Eph receptor EphA4 to enhance breast cancer stemness and promote breast tum
Externí odkaz:
https://doaj.org/article/951d591c8f644e74b61e110feda5e096
Autor:
Lei Nie, Yongkun Wei, Fei Zhang, Yi-Hsin Hsu, Li-Chuan Chan, Weiya Xia, Baozhen Ke, Cihui Zhu, Rong Deng, Jun Tang, Jun Yao, Yu-Yi Chu, Xixi Zhao, Ye Han, Junwei Hou, Longfei Huo, How-Wen Ko, Wan-Chi Lin, Hirohito Yamaguchi, Jung-Mao Hsu, Yi Yang, Dean N. Pan, Jennifer L. Hsu, Celina G. Kleer, Nancy E. Davidson, Gabriel N. Hortobagyi, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
EZH2 phosphorylation by CDK2 promotes progression of triple-negative breast cancer (TNBC). Here, the authors show that this signaling axis downregulates ERα, and thus combinatorial blockade of CDK2 and EZH2 sensitizes TNBC cells to tamoxifen.
Externí odkaz:
https://doaj.org/article/db070b7abc844972aa2cc8c48facb949
Autor:
Jung-Mao Hsu, Weiya Xia, Yi-Hsin Hsu, Li-Chuan Chan, Wen-Hsuan Yu, Jong-Ho Cha, Chun-Te Chen, Hsin-Wei Liao, Chu-Wei Kuo, Kay-Hooi Khoo, Jennifer L. Hsu, Chia-Wei Li, Seung-Oe Lim, Shih-Shin Chang, Yi-Chun Chen, Guo-xin Ren, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
PD-L1 accumulates on cancer stem cells and favours immune evasion but the mechanism underlying this accumulation are unknown. Here the authors show that epithelial-mesenchymal transition induces glycosylation and stabilisation of PD-L1; antagonising
Externí odkaz:
https://doaj.org/article/b6e5e0697fa048aeb6392035c75e7d85
Autor:
Mien-Chie Hung, Jun Qin, Yue Chen, Rosa F. Hwang, Huamin Wang, Jason B. Fleming, Chao-Kai Chou, How-Wen Ko, Weiya Xia, Shih-Shin Chang, Hsin-Wei Liao, Chia-Wei Li, Wei-Chao Chang, Hung-Ling Wang, Jennifer L. Hsu, Yi-Hsin Hsu, Shing-Jyh Chang, Pei-Chih Lee, Yongkun Wei, Ya'an Kang, Jung-Mao Hsu, Yan Wang
Correlation between Gli1 and PRMT1 Levels (S1); Identification of a PRMT1-Methylated Site in Gli1 (S2); Effects of R597 on Gli1 Transcriptional Activity (S3); Tumorigenicity of Wild-Type Gli1 and R597K-Mutated Gli1 (S4); Regulation of Gli1 by PRMT1 I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a32d0574da644c2cf06625b806b0ebe
https://doi.org/10.1158/0008-5472.22412594.v1
https://doi.org/10.1158/0008-5472.22412594.v1
Autor:
Mien-Chie Hung, Jun Qin, Yue Chen, Rosa F. Hwang, Huamin Wang, Jason B. Fleming, Chao-Kai Chou, How-Wen Ko, Weiya Xia, Shih-Shin Chang, Hsin-Wei Liao, Chia-Wei Li, Wei-Chao Chang, Hung-Ling Wang, Jennifer L. Hsu, Yi-Hsin Hsu, Shing-Jyh Chang, Pei-Chih Lee, Yongkun Wei, Ya'an Kang, Jung-Mao Hsu, Yan Wang
Enzymes from list of Gli1-binding proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41150271cc54f3a1400a3ac4101cfd1d
https://doi.org/10.1158/0008-5472.22412585
https://doi.org/10.1158/0008-5472.22412585
Autor:
Mien-Chie Hung, Jun Qin, Yue Chen, Rosa F. Hwang, Huamin Wang, Jason B. Fleming, Chao-Kai Chou, How-Wen Ko, Weiya Xia, Shih-Shin Chang, Hsin-Wei Liao, Chia-Wei Li, Wei-Chao Chang, Hung-Ling Wang, Jennifer L. Hsu, Yi-Hsin Hsu, Shing-Jyh Chang, Pei-Chih Lee, Yongkun Wei, Ya'an Kang, Jung-Mao Hsu, Yan Wang
The oncogenic transcription factor Gli1 is a critical effector in the Hedgehog (Hh) pathway, which is necessary for the development and progression of pancreatic ductal adenocarcinoma (PDAC). Although TGFβ and K-Ras are known regulators of Gli1 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01169a18e6f0c5304a6fdb06219457a5
https://doi.org/10.1158/0008-5472.c.6508469.v1
https://doi.org/10.1158/0008-5472.c.6508469.v1
Autor:
Mien-Chie Hung, Chau-Ting Yeh, Wei-Chen Lee, Tse-Ching Chen, Yi-Hsin Hsu, Chia-Wei Li, Shih-Shin Chang, Ting-Jung Wu
Supplementary Table S1. List of antibodies used for the immunoblotting, immunofluorescence, and immunohistochemistry. Supplementary Table S2. List of inhibitors used in this study with stock concentration and dilution. Supplementary Table S3. List of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4211adc8bd61c404aae1d5cc49a12ac4
https://doi.org/10.1158/1078-0432.22458974.v1
https://doi.org/10.1158/1078-0432.22458974.v1
Autor:
Mien-Chie Hung, Chau-Ting Yeh, Wei-Chen Lee, Tse-Ching Chen, Yi-Hsin Hsu, Chia-Wei Li, Shih-Shin Chang, Ting-Jung Wu
Supplementary Figure S1. Immunoblot and heatmap of EMT regulators in HCC. Supplementary Figure S2. immunofluorescence, immunoblot, and cell counting of HCC cells with or without Snail knockdown. Supplementary Figure S3. Identification of TNF-α media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddfaebb49591936f345944283dcde53
https://doi.org/10.1158/1078-0432.22458977
https://doi.org/10.1158/1078-0432.22458977
Autor:
Mien-Chie Hung, Chau-Ting Yeh, Wei-Chen Lee, Tse-Ching Chen, Yi-Hsin Hsu, Chia-Wei Li, Shih-Shin Chang, Ting-Jung Wu
Purpose: Surgical resection is considered as a curative treatment modality for hepatocellular carcinoma; however, the incidence of postoperative tumor recurrence is high, leading to worse patient survival. Persistent hepatitis (inflammation) is one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2379f1d4e6cc75154d8646f9ed14f553
https://doi.org/10.1158/1078-0432.c.6524105
https://doi.org/10.1158/1078-0432.c.6524105
Autor:
Mien-Chie Hung, Jun Qin, Yue Chen, Rosa F. Hwang, Huamin Wang, Jason B. Fleming, Chao-Kai Chou, How-Wen Ko, Weiya Xia, Shih-Shin Chang, Hsin-Wei Liao, Chia-Wei Li, Wei-Chao Chang, Hung-Ling Wang, Jennifer L. Hsu, Yi-Hsin Hsu, Shing-Jyh Chang, Pei-Chih Lee, Yongkun Wei, Ya'an Kang, Jung-Mao Hsu, Yan Wang
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216ac920271adcf5251f301be672c37b
https://doi.org/10.1158/0008-5472.22412591
https://doi.org/10.1158/0008-5472.22412591