Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Yi Han Chen"'
Autor:
Hui Xiong, Bowen Lin, Junyang Liu, Renhong Lu, Zheyi Lin, Chengwen Hang, Wenjun Liu, Lei Zhang, Jie Ding, Huixin Guo, Mingshuai Zhang, Siyu Wang, Zheng Gong, Duanyang Xie, Yi Liu, Dan Shi, Dandan Liang, Zhen Liu, Yi-Han Chen, Jian Yang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-15 (2024)
Abstract The spalt (Sal) gene family has four members (Sall1-4) in vertebrates, all of which play pivotal roles in various biological processes and diseases. However, the expression and function of SALL2 in development are still less clear. Here, we
Externí odkaz:
https://doaj.org/article/7f36bf6a9986410aa90e27140ca18bd1
A new paradigm for generating high-quality cardiac pacemaker cells from mouse pluripotent stem cells
Autor:
Zheyi Lin, Bowen Lin, Chengwen Hang, Renhong Lu, Hui Xiong, Junyang Liu, Siyu Wang, Zheng Gong, Mingshuai Zhang, Desheng Li, Guojian Fang, Jie Ding, Xuling Su, Huixin Guo, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Jian Yang, Yi-Han Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Cardiac biological pacing (BP) is one of the future directions for bradyarrhythmias intervention. Currently, cardiac pacemaker cells (PCs) used for cardiac BP are mainly derived from pluripotent stem cells (PSCs). However, the production of
Externí odkaz:
https://doaj.org/article/df6e07473b8847cf9f3322eccaafe683
Akademický článek
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Autor:
Chengwen Hang, Mohamed S. Moawad, Zheyi Lin, Huixin Guo, Hui Xiong, Mingshuai Zhang, Renhong Lu, Junyang Liu, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Yi-Han Chen, Jian Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Cardiovascular diseases (CVDs) have the highest mortality worldwide. Human pluripotent stem cells (hPSCs) and their cardiomyocyte derivatives (hPSC-CMs) offer a valuable resource for disease modeling, pharmacological screening, an
Externí odkaz:
https://doaj.org/article/3c628a341eea423facccdc0b34287cd0
Autor:
Huixin Guo, Chengwen Hang, Bowen Lin, Zheyi Lin, Hui Xiong, Mingshuai Zhang, Renhong Lu, Junyang Liu, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Jian Yang, Yi-Han Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Background Transcription factors HAND1 and HAND2 (HAND1/2) play significant roles in cardiac organogenesis. Abnormal expression and deficiency of HAND1/2 result in severe cardiac defects. However, the function and mechanism of HAND1/2 in reg
Externí odkaz:
https://doaj.org/article/3e5e1570bfcc445c934141367de89f64
Publikováno v:
IEEE Access, Vol 12, Pp 190598-190610 (2024)
This paper presents the integration of several deep learning techniques for defect inspection of plated through-hole (PTH) on printed circuit boards (PCBs). In our proposed system, the object detection technology of You Only Look Once (YOLO) allocate
Externí odkaz:
https://doaj.org/article/e002fbe0ceb04cbf95b41523b5cbbc46
Autor:
Xiuxiu Liu, Maoying Han, Wendong Weng, Yan Li, Wenjuan Pu, Kuo Liu, Xufeng Li, Lingjuan He, Ruilin Sun, Ruling Shen, Yulong He, Dandan Liang, Yi-Han Chen, Qing-Dong Wang, Jan S. Tchorz, Bin Zhou
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-7 (2023)
Abstract A genetic system, ProTracer, has been recently developed to record cell proliferation in vivo. However, the ProTracer is initiated by an infrequently used recombinase Dre, which limits its broad application for functional studies employing f
Externí odkaz:
https://doaj.org/article/003857d550184788a930ee3f005fbb6c
Autor:
Hongyu Liu, Ran Duan, Xiaoyu He, Jincu Qi, Tianming Xing, Yahan Wu, Liping Zhou, Lingling Wang, Yujing Shao, Fulei Zhang, Huixing Zhou, Xingdong Gu, Bowen Lin, Yuanyuan Liu, Yan Wang, Yi Liu, Li Li, Dandan Liang, Yi-Han Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Alternative splicing crucially affects various biological processes, however, its function in heart development is largely unknown. Here, the authors show an essential role of alternative splicing factor PTBP1 in ventricular chamber development.
Externí odkaz:
https://doaj.org/article/5098094dd0a341e888c799de0b07fb37
Publikováno v:
Science China. Life sciences. 60(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ebd20cad0b510e233548bc3dbb4b60b
https://pubmed.ncbi.nlm.nih.gov/28349305
https://pubmed.ncbi.nlm.nih.gov/28349305
Autor:
Duanyang Xie, Ke Xiong, Xuling Su, Guanghua Wang, Luxin Wang, Qicheng Zou, Caihong Zhang, Yuting Cao, Yi Liu, Yi-Han Chen
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/c62ab78c30f849ef827ec025c2652eee