Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yi Chih Chiu"'
Autor:
Meng-Hsuan Lin, Chao-Cheng Cho, Yi-Chih Chiu, Chia-Yu Chien, Yi-Ping Huang, Chi-Fon Chang, Chun-Hua Hsu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Meng-Hsuan Lin et al. investigate MERS-CoV macro domain binding selectivity with NAD and NAD metabolites under various conditions. At physiological temperature, NAD is observed to have enhanced binding affinity to the MERS-CoV macro domain, shedding
Externí odkaz:
https://doaj.org/article/c746f4f54dab40188dea1673f5a05a7b
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Poly-ADP-ribosylation (PARylation) is a well-known regulatory event in eukaryotes but has not yet been observed in bacteria. Here, the authors solve the structure of a bacterial PAR-glycohydrolase and provide evidence for a prokaryotic PARylation mac
Externí odkaz:
https://doaj.org/article/ee938e1dfa4b4d808584c20cfe83a6c4
Publikováno v:
International Journal of Biological Macromolecules. 188:914-923
Microbial urate oxidase has emerged as a potential source of therapeutic properties for hyperuricemia in arthritic gout and renal disease. The thermostability and long-term thermal tolerance of the enzyme need to be established to prolong its therape
Publikováno v:
ACS Catalysis. 11:11075-11090
Autor:
Chun-Hua Hsu, Chia-Yu Chien, Yi-Ping Huang, Chi-Fon Chang, Chao-Cheng Cho, Yi-Chih Chiu, Meng-Hsuan Lin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
The macro domain is an ADP-ribose (ADPR) binding module, which is considered to act as a sensor to recognize nicotinamide adenine dinucleotide (NAD) metabolites, including poly ADPR (PAR) and other small molecules. The recognition of macro domains wi
Publikováno v:
2022 IEEE International Conference on Imaging Systems and Techniques (IST).
Autor:
Jangam Vikram Kumar, Tien‐Sheng Tseng, Yuan‐Chao Lou, Shu‐Yi Wei, Tsung‐Han Wu, Hao‐Cheng Tang, Yi‐Chih Chiu, Chun‐Hua Hsu, Chinpan Chen
Publikováno v:
Protein Sci
In Staphylococcus aureus, vancomycin‐resistance‐associated response regulator (VraR) is a part of the VraSR two‐component system, which is responsible for activating a cell wall‐stress stimulon in response to an antibiotic that inhibits cell
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5611, p 5611 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5611, p 5611 (2021)
Volume 22
Issue 11
Urate oxidase initiates the uric acid degradation pathways and is extensively used for protein drug development for gout therapy and serum uric acid diagnosis. We first present the biochemical and structural elucidation of a urate oxidase from the ex
Publikováno v:
ACS Infectious Diseases
The pandemic outbreak of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has threatened the global public health and economy since late December 2019. SARS-CoV-2 encodes the conserved macro domain within nonstructur
Publikováno v:
Journal of structural biology. 212(1)
BCP1 is a protein enriched in the nucleus that is required for Mss4 nuclear export and identified as the chaperone of ribosomal protein Rpl23 in Saccharomyces cerevisiae. According to sequence homology, BCP1 is related to the mammalian BRCA2-interact