Zobrazeno 1 - 10 of 82 pro vyhledávání: '"Yi Chien Tsai"'
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Akademický článek
MHC-I upregulation safeguards neoplastic T cells in the skin against NK cell-mediated eradication in mycosis fungoides
Autor: Yun-Tsan Chang, Pacôme Prompsy, Susanne Kimeswenger, Yi-Chien Tsai, Desislava Ignatova, Olesya Pavlova, Christoph Iselin, Lars E. French, Mitchell P. Levesque, François Kuonen, Malgorzata Bobrowicz, Patrick M. Brunner, Steve Pascolo, Wolfram Hoetzenecker, Emmanuella Guenova
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer-associated immune dysfunction is a major challenge for effective therapies. The emergence of antibodies targeting tumor cell-surface antigens led to advancements in the treatment of hematopoietic malignancies, particularly blood cance
Externí odkaz: https://doaj.org/article/1a3bf0a991644740869501ab71bb08ef
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3
Akademický článek
Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets
Autor: Monika Ettinger, Teresa Burner, Anshu Sharma, Yun-Tsan Chang, Angelika Lackner, Pacôme Prompsy, Isabella M. Deli, Judith Traxler, Gerald Wahl, Sabine Altrichter, Rupert Langer, Yi-Chien Tsai, Suraj R. Varkhande, Leonie C. Schoeftner, Christoph Iselin, Iris K. Gratz, Susanne Kimeswenger, Emmanuella Guenova, Wolfram Hoetzenecker
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Darier disease (DD) is a rare, inherited multi-organ disorder associated with mutations in the ATP2A2 gene. DD patients often have skin involvement characterized by malodorous, inflamed skin and recurrent, severe infections. Therapeutic opti
Externí odkaz: https://doaj.org/article/8eec8722afcf4e4cb83878c6585c3720
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