Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yi Caudle"'
Autor:
Yanxiao Xiang, Hui Yan, Jun Zhou, Qi Zhang, Gregory Hanley, Yi Caudle, Gene LeSage, Xiumei Zhang, Deling Yin
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123447 (2015)
Emerging evidence implied that chronic stress has been exerting detrimental impact on immune system functions in both humans and animals. Toll-like receptors (TLRs) have been shown to play an essential role in modulating immune responses and cell sur
Externí odkaz:
https://doaj.org/article/53841f37c0cf429c898c05e3bd9cdc94
Publikováno v:
J Infect Dis
Publikováno v:
The Journal of Infectious Diseases. 218:300-311
BackgroundmicroRNA-23b (miR-23b) is a multiple functional miRNA. We hypothesize that miR-23b plays a role in the pathogenesis of sepsis. Our study investigated the effect of miR-23b on sepsis-induced immunosuppression.MethodsMice were treated with mi
Publikováno v:
Journal of Neuroimmunology. 314:30-41
Depending on the duration and severity, psychological tension and physical stress can enhance or suppress the immune system in both humans and animals. Although it has been established that chronic stress exerts a significant suppressive effect on im
Autor:
James Denney, Hui Yan, Deling Yin, Yi Caudle, Charles A. Stuart, Gene LeSage, Ronald C. Hamdy, Krishna Singh, Christopher R. Daniels, Hui Li, Balvin H.L. Chua
Publikováno v:
Biochemistry and Biophysics Reports
Sepsis is an exaggerated systemic inflammatory response to persistent bacteria infection with high morbidity and mortality rate clinically. β-arrestin 2 modulates cell survival and cell death in different systems. However, the effect of β-arrestin
Publikováno v:
Apoptosis. 21:546-557
Elevated circulatory free fatty acids (FFAs) especially saturated FFAs, such as palmitate (PA), are detrimental to the heart. However, mechanisms responsible for this phenomenon remain unknown. Here, the role of JAK2/STAT3 in PA-induced cytotoxicity
Publikováno v:
The Journal of Immunology. 204:78.4-78.4
Psychological and physical stress can suppress the immune system in both humans and animals. The mechanism by which stress affects immune responses, however, remains poorly defined. Recent evidence demonstrated that nitric oxide (NO) modulates cell-m
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 103
Cardiovascular dysfunction is a major complication associated with sepsis induced mortality. Cardiac fibrosis plays a critical role in sepsis induced cardiac dysfunction. The mechanisms of the activation of cardiac fibrosis is unclarified. In this st
Autor:
Hui Li, Xiumei Zhang, Jun Zhou, Deling Yin, Dan Hu, Yi Caudle, Yianxiao Xiang, Xiaohua Yang, Hui Yan
Publikováno v:
Cellular Immunology. 295:92-98
Sepsis, a major clinical problem with high morbidity and mortality, is caused by overwhelming systemic host-inflammatory response. Toll-like receptors (TLRs) play a fundamental role in induction of hyperinflammation and tissue damage in sepsis. In th
Autor:
Lei He, Deling Yin, Yimin Feng, Ying Zhang, Yi Caudle, Shuwei Qiu, Yi Li, Charles A. Stuart, Gene LeSage, Ying Peng
Publikováno v:
The Journal of Immunology. 194:1021-1030
Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects including immunosuppression. However, the mechanisms are unclear. TLRs and acetylcholine are wid