Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yi‐Xi Liu"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Numerous vancomycin population pharmacokinetic models in neonates have been published; however, their predictive performances remain unknown. This study aims to evaluate their external predictability and explore the factors that might aff
Externí odkaz:
https://doaj.org/article/aa4f4e795fde45a5901f06aa698a1926
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundDepending on the renal function of patients and many other influencing factors, studies on vancomycin pharmacokinetics show significant inter- and intra-individual variability. The present study was conducted using a population pharmacokine
Externí odkaz:
https://doaj.org/article/b918d0235cbf43b784e12951fe88a326
Autor:
Zhi-ling Li, Yi-xi Liu, Zheng Jiao, Gang Qiu, Jian-quan Huang, Yu-bo Xiao, Shu-jin Wu, Chen-yu Wang, Wen-juan Hu, Hua-jun Sun
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The main goal of our study was to characterize the population pharmacokinetics of vancomycin in critically ill Chinese neonates to develop a pharmacokinetic model and investigate factors that have significant influences on the pharmacokinetics of van
Externí odkaz:
https://doaj.org/article/dfc61ab9ec134ef3869d5d084cf58b96
Publikováno v:
Chemical Science. 14:3493-3500
A copper-catalyzed asymmetric cascade cyclization via C(sp2)–O bond cleavage is disclosed, affording a range of chromeno[3,4-c]pyrroles bearing a triaryl oxa-quaternary carbon stereocenter in high yields and enantioselectivities.
Publikováno v:
Angewandte Chemie. 135
Publikováno v:
Chemical Science.
An organocatalytic intramolecular (4 + 2) annulation of enals with ynamides is disclosed, providing a convenient way to axially chiral indolines. The synthesized axially chiral skeleton was proved to be potentially applicable as a chiral ligand.
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 167
Background Efavirenz is a vital component used to treat HIV-1 infection. Nevertheless, it shows large between-subject variability, which affects both its therapeutic response and adverse effects. Objective To investigate the impact of gene polymorphi
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Background Depending on the renal function of patients and many other influencing factors, studies on vancomycin pharmacokinetics show significant inter- and intra-individual variability. The present study was conducted using a population pharmacokin
ObjectivePyrotinib, a novel oral irreversible dual pan-ErbB tyrosine kinase inhibitor (TKI), has been approved in China for the treatment of HER2-positive advanced or metastatic breast cancer. This study aimed to conduct a population pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e391516fd520a90c5ad62755a028b3
Publikováno v:
Zhongguo Dang Dai Er Ke Za Zhi
OBJECTIVE: To evaluate the efficacy and safety of C-reactive protein (CRP)-guided antibiotic treatment strategy for neonates with suspected early-onset sepsis (EOS). METHODS: A total of 428 neonates, with a gestational age of > 35 weeks, who were adm