Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Yi‐Min Sun"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Single-cell RNA sequencing (scRNA-seq) has emerged as a pivotal tool for exploring cellular landscapes across diverse species and tissues. Precise annotation of cell types is essential for understanding these landscapes, relying heavily on e
Externí odkaz:
https://doaj.org/article/48b3be47033d4f3aaf8d7f08531fdf48
Autor:
Fan-Lin Meng, Xiao-Ling Huang, Wen-Yan Qin, Kun-Bang Liu, Yan Wang, Ming Li, Yong-Hong Ren, Yan-Ze Li, Yi-Min Sun
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Annotating cells in the analysis of single-cell RNA-seq (scRNA-seq) data is one of the most challenging tasks that researchers are actively addressing. Manual cell annotation is generally considered the gold standard method, although it is l
Externí odkaz:
https://doaj.org/article/29f959646e334d26b1aa7492cfe319d1
Autor:
Yi-Min Sun, Xin-Yue Zhou, Xiao-Niu Liang, Jin-Ran Lin, Yi-Dan Xu, Chen Chen, Si-Di Wei, Qi-Si Chen, Feng-Tao Liu, Jue Zhao, Yi-Lin Tang, Bo Shen, Lin-Hua Gan, Boxun Lu, Zheng-Tong Ding, Yu An, Jian-Jun Wu, Jian Wang
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract So far, over 20 causative genes of monogenic Parkinson’s disease (PD) have been identified. Some causative genes of non-parkinsonian entities may also manifest with parkinsonism mimicking PD. This study aimed to investigate the genetic cha
Externí odkaz:
https://doaj.org/article/e271155b6d364fe2ace5dd21d8814500
Autor:
Xin-Hua Wu, Yang-Yang He, Zhang-Rong Chen, Ze-Yuan He, Yi Yan, Yangzhige He, Guang-Ming Wang, Yu Dong, Ying Yang, Yi-Min Sun, Yong-Hong Ren, Qiu-Yan Zhao, Xiao-Dan Yang, Li-Ying Wang, Cai-Jun Fu, Miao He, Si-Jin Zhang, Ji-Fen Fu, Hong Liu, Zhi-Cheng Jing
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Single cell transcriptomic sequencing (scRNA) can identify genes that are differentially expressed in cell populations in specific diseases. Here the authors perform scRNA sequencing in a high-altitude pulmonary hypertension (HAPH) cohort and show tr
Externí odkaz:
https://doaj.org/article/fd2e031871344431a25f4ada3f8a4986
Autor:
Lin‐Lin Han, Lan Wang, Zhi‐Heng Xu, Xiao‐Niu Liang, Meng‐Wei Zhang, Yun Fan, Yi‐Min Sun, Feng‐Tao Liu, Wen‐Bo Yu, Yi‐Lin Tang
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 2096-2104 (2021)
Abstract Objective Little is known about the disease progression of Parkinson's disease patients with subjective cognitive complaint (PD‐SCC). This longitudinal cohort study aims to compare the progression of clinical features and quality of life (
Externí odkaz:
https://doaj.org/article/7b300f29e396406bae0a0a7b1a8817d9
Autor:
Chen Chen, Min-Min Lou, Yi-Min Sun, Fang Luo, Feng-Tao Liu, Su-Shan Luo, Wen-Yuan Wang, Jian Wang
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionPhospholipase A2 Group VI (PLA2G6), encoding calcium-independent phospholipase A2, has been isolated as the gene responsible for an autosomal recessive form of early-onset Parkinson’s disease (namely, PARK14). Compared to idiopathic Par
Externí odkaz:
https://doaj.org/article/9e5ae1f8fe7847e98139a8dc746699bd
Publikováno v:
Clinical and Translational Neuroscience, Vol 7, Iss 2, p 11 (2023)
Background: Genetic and epigenetic modifiers of age at onset of Parkinson’s disease (PD) are largely unknown. It remains unclear whether DNA methylation (DNAm) age acceleration is linked to age at onset in PD patients of different ethnicities with
Externí odkaz:
https://doaj.org/article/fc52d68646e54f7484c54cf85b5b9667
Publikováno v:
Геодинамика и тектонофизика, Vol 10, Iss 2, Pp 507-539 (2019)
The modern theory of the evolving Earth is based on integrated isotopic data obtained for the accessible part of the planet and cosmic bodies, in which the U–Pb isotope system plays a key role. The theory is tested by the isotope systematics of oce
Externí odkaz:
https://doaj.org/article/01fc5ddebd9440f99c441ae4cf0b9143
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-9 (2019)
Abstract Background Hereditary spastic paraplegias (HSP) are of great clinical and genetic heterogeneity. According to the clinical features, HSP can be divided into pure or complicated subtypes which combined with other neurological symptoms includi
Externí odkaz:
https://doaj.org/article/620c1def2d544750b812461acbd4e768
Autor:
Cong Shen, Li Chen, Jing-Jie Ge, Jia-Ying Lu, Qi-Si Chen, Shu-Jin He, Xin-Yi Li, Jue Zhao, Yi-Min Sun, Ping Wu, Jian-Jun Wu, Feng-Tao Liu, Jian Wang
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: We aimed to characterize the cognitive profiles in multiple system atrophy (MSA) and explore the cerebral metabolism related to the cognitive decline in MSA using 18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography (PET).Methods:
Externí odkaz:
https://doaj.org/article/b80ca0a21bf5429db6a142a33e9d0055