Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yi, Patel"'
Publikováno v:
Europe PubMed Central
Although the role of CD28 in T cell costimulation is firmly established, the mechanisms by which it exerts its costimulatory actions are less clear. In many circumstances it is difficult to distinguish the effects of CD28 from subsequent actions of c
Publikováno v:
Europe PubMed Central
A major obstacle in understanding the signaling events that follow CD28 receptor ligation arises from the fact that CD28 acts as a costimulus to TCR engagement, making it difficult to assess the relative contribution of CD28 signals as distinct from
Publikováno v:
Europe PubMed Central
Ag recognition is an essential component for an effective T cell response. However, T cell activation is also subject to additional regulation by accessory molecules. CD28 provides essential costimulatory signals that allow T cells to proliferate, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bc30fb5a60971ea2a438679669ce6ece
http://europepmc.org/abstract/med/9498743
http://europepmc.org/abstract/med/9498743
Publikováno v:
Europe PubMed Central
CD28 and CTLA-4 are related receptors that differentially regulate T cell activation. Despite the fact that they bind the same ligands, CD28 is a classical costimulator enhancing proliferation whereas CTLA-4 appears to perform negative regulatory fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::35977e47297b34f463d2c3f767a1a2f6
http://europepmc.org/abstract/med/9780158
http://europepmc.org/abstract/med/9780158
Autor:
Patel YI; Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA., Natarajan S; Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA., Ramakrishna S; Pulmonary and Critical Care Medicine, Geisinger Commonwealth School of Medicine, Scranton, USA., Ochieng P; Pulmonary and Critical Care Medicine, Geisinger Commonwealth School of Medicine, Scranton, USA.
Publikováno v:
Cureus [Cureus] 2023 May 28; Vol. 15 (5), pp. e39613. Date of Electronic Publication: 2023 May 28 (Print Publication: 2023).
Autor:
Jena A; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Mishra S; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Deepak P; Inflammatory Bowel Diseases Center, Division of Gastroenterology,Washington University in Saint Louis School of Medicine, St. Louis, MO, USA. Electronic address: deepak.parakkal@wustl.edu., Kumar-M P; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Sharma A; Clinical Immunology and Rheumatology Wing, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Patel YI; Department of Rheumatology, Hull University Teaching Hospitals NHS Trust, Hull, UK. Electronic address: yusuf.patel9@nhs.net., Kennedy NA; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK. Electronic address: nick.kennedy1@nhs.net., Kim AHJ; Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: akim@wustl.edu., Sharma V; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Electronic address: sharma.vishal@pgimer.edu.in., Sebastian S; IBD Unit - Gastroenterology, Hull University Teaching Hospitals NHS Trust, Hull, UK. Electronic address: shaji.sebastian4@nhs.net.
Publikováno v:
Autoimmunity reviews [Autoimmun Rev] 2022 Jan; Vol. 21 (1), pp. 102927. Date of Electronic Publication: 2021 Aug 30.
Autor:
Choy E; CREATE Centre, Division of Infection and Immunity, Cardiff University School of Medicine, Wales, UK.; Cardiff and Vale University Health Board, Cardiff, Wales, UK., Groves L; Health Economics and Outcomes Research Ltd, Cardiff, UK., Sugrue D; Health Economics and Outcomes Research Ltd, Cardiff, UK., Hurst M; Health Economics and Outcomes Research Ltd, Cardiff, UK., Houghton J; Health Economics and Outcomes Research Ltd, Cardiff, UK., Venkatachalam S; Cannock and Wolverhampton Rheumatology Centre, The Royal Wolverhampton NHS Trust, Wolverhampton, UK., Patel YI; Hull University Teaching Hospitals NHS Trust, Hull, UK., Maxwell JR; Sheffield Teaching Hospitals, Sheffield, UK., Pollock KG; Bristol Myers Squibb, Uxbridge Business Park, Sanderson Road, Uxbridge, Middlesex, UK., Henning S; Bristol Myers Squibb, Uxbridge Business Park, Sanderson Road, Uxbridge, Middlesex, UK. sadie.henning@bms.com.
Publikováno v:
BMC rheumatology [BMC Rheumatol] 2021 Feb 04; Vol. 5 (1), pp. 3. Date of Electronic Publication: 2021 Feb 04.
Autor:
Isaacs JD; Arthritis Research UK Experimental Arthritis Treatment Centre, Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne.; Musculoskeletal Unit, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne., Salih A; Warrington and Halton Hospitals NHS Foundation Trust, Warrington Hospital, Warrington., Sheeran T; Rheumatology Centre, Cannock Chase Hospital, Cannock., Patel YI; Department of Rheumatology, Hull Royal Infirmary, Hull., Douglas K; Department of Rheumatology, Dudley Group NHS Foundation Trust, Dudley., McKay ND; Rheumatic Diseases Unit, Western General Hospital, Edinburgh., Naisbett-Groet B; Roche Products Ltd, Welwyn Garden City., Choy E; CREATE Centre, Division of Infection and Immunity, Cardiff University, Cardiff, UK.
Publikováno v:
Rheumatology advances in practice [Rheumatol Adv Pract] 2019 Apr 19; Vol. 3 (1), pp. rkz010. Date of Electronic Publication: 2019 Apr 19 (Print Publication: 2019).
Publikováno v:
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2000 Feb; Vol. 39 (2), pp. 119-21.
Publikováno v:
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2000 Jan; Vol. 39 (1), pp. 108-10.