Zobrazeno 1 - 10 of 1 020 pro vyhledávání: '"Yh, Lai"'
1
Akademický článek
Current Approaches to Vaccine Safety Using Observational Data: A Rationale for the EUMAEUS (Evaluating Use of Methods for Adverse Events Under Surveillance-for Vaccines) Study Design
Autor: Lana YH Lai, Faaizah Arshad, Carlos Areia, Thamir M. Alshammari, Heba Alghoul, Paula Casajust, Xintong Li, Dalia Dawoud, Fredrik Nyberg, Nicole Pratt, George Hripcsak, Marc A. Suchard, Dani Prieto-Alhambra, Patrick Ryan, Martijn J. Schuemie
Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)
Post-marketing vaccine safety surveillance aims to detect adverse events following immunization in a population. Whether certain methods of surveillance are more precise and unbiased in generating safety signals is unclear. Here, we synthesized infor
Externí odkaz: https://doaj.org/article/88f0b5452bdf4998868c6da1aeec7fb7
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2
Akademický článek
Bias, Precision and Timeliness of Historical (Background) Rate Comparison Methods for Vaccine Safety Monitoring: An Empirical Multi-Database Analysis
Autor: Xintong Li, Lana YH Lai, Anna Ostropolets, Faaizah Arshad, Eng Hooi Tan, Paula Casajust, Thamir M. Alshammari, Talita Duarte-Salles, Evan P. Minty, Carlos Areia, Nicole Pratt, Patrick B. Ryan, George Hripcsak, Marc A. Suchard, Martijn J. Schuemie, Daniel Prieto-Alhambra
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Using real-world data and past vaccination data, we conducted a large-scale experiment to quantify bias, precision and timeliness of different study designs to estimate historical background (expected) compared to post-vaccination (observed) rates of
Externí odkaz: https://doaj.org/article/7abbd4f540e14f1282e22242e106df3b
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5
Baseline phenotype and 30-day outcomes of people tested for COVID-19: an international network cohort including >3.32 million people tested with real-time PCR and >219,000 tested positive for SARS-CoV-2 in South Korea, Spain and the United States
Autor: Jason Thomas, Kristin Kostka, Carlos Areia, Paula Casajust, Andrew E. Williams, Mengchun Gong, Anna Ostropolets, George Hripcsak, Scott L. DuVall, Marc A. Suchard, Peter R. Rijnbeek, Jennifer C E Lane, Martina Recalde, Daniel R. Morales, Jose D. Posada, Adam B. Wilcox, Maria Tereza Fernandes Abrahão, Osaid Alser, Clair Blacketer, Fredrik Nyberg, Ying Zhang, Anthony G. Sena, Christian G. Reich, Sergio Fernandez-Bertolin, Patrick B. Ryan, Lin Zhang, Jitendra Jonnagaddala, Thomas Falconer, Seng Chan You, David Vizcaya, Frank J. DeFalco, Vignesh Subbian, Michael E. Matheny, Karthik Natarajan, Waheed-Ul-Rahman Ahmed, Asieh Golozar, Thamir M. Alshammari, Hamed Abedtash, Heba Alghoul, Lana Yh Lai, Matthew E. Spotnitz, Elena Roel, Alan Andryc, Nigam H. Shah, Vojtech Huser, Kristine E. Lynch, Karishma Shah, Yin Guan, Stephen Fortin, Talita Duarte-Salles, Daniel Prieto-Alhambra, Lisa M. Schilling, Albert Prats-Uribe
Publikováno v: medRxiv
Early identification of symptoms and comorbidities most predictive of COVID-19 is critical to identify infection, guide policies to effectively contain the pandemic, and improve health systems’ response. Here, we characterised socio-demographics an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf23ce20f05a189682ab7386b0a03126
https://zenodo.org/record/4428299
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6
In vivo effect of endothelin-1 on plasma calcium and parathyroid hormone concentrations
Autor: SJ Hwang, JC Tsai, Chang Jm, YH Lai
Publikováno v: Journal of Endocrinology. 165:179-184
We have previously reported an in vitro inhibitory effect of endothelin-1 (ET-1) on parathyroid hormone (PTH) secretion. In the present experiment, ET-1 was infused into rabbits to study the in vivo effect of ET-1 on the changes in calcium, magnesium
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2968ca58361ae56797f336a8df4af27c
https://doi.org/10.1677/joe.0.1650179
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7
Prediction of equilibrated postdialysis BUN by an artificial neural network in high-efficiency hemodialysis
Autor: CY Yang, YH Lai, Jinn-Yuh Guh, LM Chen, JM Yang
Publikováno v: American Journal of Kidney Diseases. 31:638-646
In urea kinetic modeling, postdialysis blood urea nitrogen (BUN) is usually underestimated with an overestimation of the Kt/V especially in high-efficiency hemodialysis (HD). Thus, an artificial neural network (ANN) was used to predict the equilibrat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1427787151f8358702b7893bc993b495
https://doi.org/10.1053/ajkd.1998.v31.pm9531180
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8
Traditional Chinese medicines as immunosuppressive agents
Autor: Ramgolam V, Sg, Ang, Yh, Lai, Cs, Loh, Hui Kim Yap
Publikováno v: Europe PubMed Central
Traditional Chinese Medicines (TCM) have been used for centuries in China to treat various immune-mediated disorders.This review focuses on the clinical and experimental studies that have been performed with TCM as immunosuppressive agents for the tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::863ddc6be348372090985ca20c969b5a
https://pubmed.ncbi.nlm.nih.gov/10748958
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9
Photochemical and Thermal Decomposition of Bis(3-chloro-2-methylphenyl)diazomethane
Autor: YH Lai
Publikováno v: Australian Journal of Chemistry. 44:1151
The reactions of diarylcarbene (2c) generated from the photolytic and thermal decomposition of diaryldiazomethane (1c) were investigated. The effect of steric hindrance in (2c) was insufficient to stabilize the carbene under the photolytic conditions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::359b3770b9489d5a424e0d38a2d7e842
https://doi.org/10.1071/ch9911151
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