One-pot sequential functionalizations of meso-tetrathienylporphyrins via Heck–Mizoroki cross-coupling reactions

Autor: Ygor W. Vieira, Timothy J. Brocksom, Edson R. Leite, Maria Carolina Donatoni, Adriano C. Rabelo, Kleber T. de Oliveira

Publikováno v: Tetrahedron Letters. 57:3016-3020

Synthesis and sequential functionalizations of a new meso -tetraiodo(thien-2-yl)porphyrin and its Ni(II) derivative are described. The reactions for the preparation of these new porphyrins were optimized. Subsequently, four successive one-pot Heck–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d48a434bc4d52b2388a61d03cd9edc4
https://doi.org/10.1016/j.tetlet.2016.05.106

Anticonvulsant activity of thymoquinone and its structural analogues

Autor: Camila Carolina de Menezes Patrício Santos, Damião Pergentino de Sousa, Franklin F. F. Nóbrega, Reinaldo Nóbrega de Almeida, Rubens Batista Benedito, Marciana P. Uliana, Ygor W. Vieira, Timothy J. Brocksom

Publikováno v: Revista Brasileira de Farmacognosia, Vol 21, Iss 3, Pp 427-431 (2011)
Revista Brasileira de Farmacognosia, Vol 21, Iss 3, Pp 427-431 (2010)
Revista Brasileira de Farmacognosia v.21 n.3 2011
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
Revista Brasileira de Farmacognosia, Volume: 21, Issue: 3, Pages: 427-431, Published: 18 MAR 2010

It has been widely reported that the crude oil of Nigella sativa L., Ranunculaceae, seeds and its major chemical component thymoquinone present anticonvulsant activity. These facts led us to verify the pharmacological potential of five structurally r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051d9bc7b9e5320ce9cf009d3697060d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300012

Unequivocal structural assignments of three cycloheptenoid intermediates for guaiane sesquiterpenes: an experimental and theoretical approach

Autor: Layla R, Barbosa, Ygor W, Vieira, Valdemar, Lacerda, Kleber T, de Oliveira, Reginaldo B, dos Santos, Sandro J, Greco, Alvaro C, Neto, Eustaquio V R, de Castro, Timothy J, Brocksom

Publikováno v: Magnetic resonance in chemistry : MRC. 52(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0635eb4a66af4e13d0c3ef8929ff9e98
https://pubmed.ncbi.nlm.nih.gov/24723362

Antinociceptive Activity of Thymoquinone and its Structural Analogues: A Structure-Activity Relationship Study

Autor: Damião Pergentino de Sousa, Marciana P. Uliana, Ccmp Santos, R.N. de Almeida, Fff Nóbrega, Rubens Batista Benedito, Ygor W. Vieira, Timothy J. Brocksom

Publikováno v: Tropical Journal of Pharmaceutical Research; Vol 11, No 4 (2012); 605-610

Purpose: To investigate the structural features that influence the antinociceptive activity of thymoquinone and their structural analogues. Methods: The quinones were prepared by an oxidation procedure using molecular oxygen and catalysis with [CoII(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de98080892a9c65a67b06bd9767f9426
https://www.ajol.info/index.php/tjpr/article/view/80570

Oxidation of mono-phenols to para-benzoquinones: a comparative study

Autor: Maria Carolina Donatoni, Arlene G. Corrêa, Marciana P. Uliana, Ygor W. Vieira, Timothy J. Brocksom, Ursula Brocksom

Publikováno v: Journal of the Brazilian Chemical Society v.19 n.8 2008
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 19, Issue: 8, Pages: 1484-1489, Published: 2008
ResearcherID

The oxidation of mono-phenols to para-benzoquinones is of continuing interest due to the existence of numerous natural products containing this structural unit. The chemical reactivity of para-benzoquinones is also noteworthy, as oxidants and dienoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b1ed1453d05b03f6085afcb72f7332
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000800007