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TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs.

Autor: Suzuki S; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan., Sargent RG; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; California Pacific Medical Center Research Institute, San Francisco, California, USA., Illek B; Childrens Hospital Oakland Research Institute, Oakland, California, USA., Fischer H; Childrens Hospital Oakland Research Institute, Oakland, California, USA., Esmaeili-Shandiz A; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA., Yezzi MJ; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; California Pacific Medical Center Research Institute, San Francisco, California, USA., Lee A; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; Present address: Graduate Program in Biochemistry, Molecular, Cellular, and Developmental Biology, University of California-Davis, Davis, California, USA., Yang Y; California Pacific Medical Center Research Institute, San Francisco, California, USA.; Present address: Molecular Department, Hunter Laboratories, Campbell, California, USA., Kim S; Liver Center, University of California-San Francisco, San Francisco, California, USA.; Present address: Heinrich-Heine-Universität Düsseldorf, Institut für Genetik, Düsseldorf, Germany., Renz P; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; California Pacific Medical Center Research Institute, San Francisco, California, USA.; Present address: Graduate Program in the Department of Biosystems Science and Engineering, ETH, Zürich, Switzerland., Qi Z; Department of Laboratory Medicine, University of California-San Francisco, San Francisco, California, USA., Yu J; Department of Laboratory Medicine, University of California-San Francisco, San Francisco, California, USA., Muench MO; Department of Laboratory Medicine, University of California-San Francisco, San Francisco, California, USA.; Liver Center, University of California-San Francisco, San Francisco, California, USA.; Blood Systems Research Institute, San Francisco, California, USA., Beyer AI; Blood Systems Research Institute, San Francisco, California, USA., Guimarães AO; Blood Systems Research Institute, San Francisco, California, USA., Ye L; Department of Medicine, University of California-San Francisco, San Francisco, California, USA., Chang J; Department of Medicine, University of California-San Francisco, San Francisco, California, USA., Fine EJ; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Cradick TJ; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Bao G; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA., Rahdar M; Department of Pediatrics, Stanford University, Stanford, California, USA., Porteus MH; Department of Pediatrics, Stanford University, Stanford, California, USA., Shuto T; Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan., Kai H; Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan., Kan YW; Department of Medicine, University of California-San Francisco, San Francisco, California, USA.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Helen Diller Family Comprehensive Cancer Center, Institute for Human Genetics, Cardiovascular Research Institute, University of California-San Francisco, San Francisco, California, USA., Gruenert DC; Department of Otolaryngology - Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; California Pacific Medical Center Research Institute, San Francisco, California, USA.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Helen Diller Family Comprehensive Cancer Center, Institute for Human Genetics, Cardiovascular Research Institute, University of California-San Francisco, San Francisco, California, USA.; Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont, USA.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2016 Jan 05; Vol. 5, pp. e273. Date of Electronic Publication: 2016 Jan 05.