Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells

Autor: Chopard, Christophe, Tong, Phuoc Bao Viet, Toth, Petra, Schatz, Malvina, Yezdi, Hocine, Debaisieux, Solène, Mettling, Clément, Gross, Antoine, Pugniere, Martine, Tu, Annie, Strub, Jean Marc, Mesnard, Jean-Michel, Vitale, Nicolas, Beaumelle, Bruno

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, 2018, 9 (1), pp.2251. ⟨10.1038/s41467-018-04674-y⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.2251. ⟨10.1038/s41467-018-04674-y⟩
Nature Communications, 2018, 9
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-04674-y⟩

Most HIV-1 Tat is unconventionally secreted by infected cells following Tat interaction with phosphatidylinositol (4,5) bisphosphate (PI(4,5)P2) at the plasma membrane. Extracellular Tat is endocytosed by uninfected cells before escaping from endosom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9ac8b602dd05d826b05f6c2a35180a46
https://hal.archives-ouvertes.fr/hal-02655916