Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yexuan Yin"'
Autor:
Ling Wang, Zongliang Jiang, Delun Huang, Jingyue Duan, Chang Huang, Shannon Sullivan, Kaneha Vali, Yexuan Yin, Ming Zhang, Jill Wegrzyn, Xiuchun ( Cindy) Tian, Young Tang
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background The generation of induced pluripotent stem cells (iPSCs) has underdefined mechanisms. In addition, leukemia inhibitory factor (LIF) activated Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway is t
Externí odkaz:
https://doaj.org/article/1ab3031e31694fb7a4ff72bc39cdbd57
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 88-97 (2017)
The development of human induced pluripotent stem cells (iPSCs) holds great promise for regenerative medicine. However the iPSC induction efficiency is still very low and with lengthy reprogramming process. We utilized the highly potent transactivati
Externí odkaz:
https://doaj.org/article/3aa540e1de9843c19a33f02a1c2ecc84
Publikováno v:
Biology Open, Vol 8, Iss 12 (2019)
Human cell reprogramming remains extremely inefficient and the underlying mechanisms by different reprogramming factors are elusive. We found that NANOG and LIN28 (NL) synergize to improve OCT4, SOX2, KLF4 and MYC (OSKM)-mediated reprogramming by ∼
Externí odkaz:
https://doaj.org/article/ec32544efc6041bfbbd18dd64f5c1309
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 88-97 (2017)
The development of human induced pluripotent stem cells (iPSCs) holds great promise for regenerative medicine. However the iPSC induction efficiency is still very low and with lengthy reprogramming process. We utilized the highly potent transactivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c7ac3b306be39c33b336150aaef509
https://doi.org/10.1016/j.scr.2017.10.014
https://doi.org/10.1016/j.scr.2017.10.014
Publikováno v:
Biology Open, Vol 8, Iss 12 (2019)
Biology Open
Biology Open
Human cell reprogramming remains extremely inefficient and the underlying mechanisms by different reprogramming factors are elusive. We found that NANOG and LIN28 (NL) synergize to improve OCT4, SOX2, KLF4 and MYC (OSKM)-mediated reprogramming by ∼
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c294fc3f7cd30ab85d242d6d8d780cf5
http://bio.biologists.org/content/8/12/bio047225
http://bio.biologists.org/content/8/12/bio047225
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
FOXH1 is a primitive-streak specifier and ACTIVIN co-effector that plays an important role in development, and positively regulates the generation of human induced pluripotent stem cells (iPSCs) from somatic cells by OCT4, SOX2, KLF4, and MYC (OSKM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b4081e0d967a4083b6480e331a1452
https://doi.org/10.1038/s41598-019-52861-8
https://doi.org/10.1038/s41598-019-52861-8
Autor:
Alexander Chu, Antonio E. Garmendia, Chang Huang, Young Tang, Ling Wang, Kaneha Vali, Yexuan Yin, Jiaqi Zhu
Publikováno v:
Antiviral Research. 183:104937
Porcine reproductive and respiratory syndrome (PRRS), caused by PRRS virus (PRRSV) infection, imposes enormous economic impact to the world pork industry. Currently there is no effective treatment to prevent PRRSV infection in swine. We report that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ded2a808ded865907f4ffda7cc9f75
https://doi.org/10.1016/j.antiviral.2020.104937
https://doi.org/10.1016/j.antiviral.2020.104937
Autor:
Wang, Ling, Zongliang Jiang, Delun Huang, Jingyue Duan, Huang, Chang, Sullivan, Shannon, Kaneha Vali, Yexuan Yin, Zhang, Ming, Wegrzyn, Jill, Xiuchun Tian, Tang, Young
JAK/STAT3 Activity Is Needed to Activate Pluripotent Loci in Reprogramming. DNA methylation of Nanog promoter region measured by bisulfite sequencing for samples described in Fig. 6b. Filled and open circles represent methylated and unmethylated CpGs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14c6e1feb4320ce04a394a734cf66fa
