Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yexin Ouyang"'
Publikováno v:
Archives of Biochemistry and Biophysics. :1-11
FRET was used to investigate the structural and kinetic effects that PKC phosphorylations exert on Ca 2+ and myosin subfragment-1 dependent conformational transitions of the cardiac thin filament. PKC phosphorylations of cTnT were mimicked by glutama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a522e10132b2c75c0501fa45c58d97
https://doi.org/10.1016/j.abb.2014.03.013
https://doi.org/10.1016/j.abb.2014.03.013
Publikováno v:
Archives of Biochemistry and Biophysics. 537:198-209
The in situ structural coupling between the cardiac troponin (cTn) Ca 2+ -sensitive regulatory switch (CRS) and strong myosin cross-bridges was investigated using Forster resonance energy transfer (FRET). The double cysteine mutant cTnC(T13C/N51C) wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e544506de847502988f90bb2fb1b496
https://doi.org/10.1016/j.abb.2013.07.013
https://doi.org/10.1016/j.abb.2013.07.013
Publikováno v:
Analytical Biochemistry. 432:106-114
A rapid assay operable under isothermal or nonisothermal conditions is described, where the sensitivity of a typical molecular beacon (MB) system is improved by using thermostable RNase H to enzymatically cleave an MB composed of a DNA stem and an RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f939778505b1d06057a143c9e35a35
https://doi.org/10.1016/j.ab.2012.09.015
https://doi.org/10.1016/j.ab.2012.09.015
Publikováno v:
Journal of Biological Chemistry. 287:7661-7674
The regulatory function of cardiac troponin I (cTnI) involves three important contiguous regions within its C-domain: the inhibitory region (IR), the regulatory region (RR), and the mobile domain (MD). Within these regions, the dynamics of regional s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfbc8b0314bd56c926d2b8da0ec089c
https://doi.org/10.1074/jbc.m111.281600
https://doi.org/10.1074/jbc.m111.281600
Publikováno v:
Journal of Molecular Biology. 400:1036-1045
Residue Ser151 of cardiac troponin I (cTnI) is known to be phosphorylated by p21-activated kinase 3 (PAK3). It has been found that PAK3-mediated phosphorylation of cTnI induces an increase in the sensitivity of myofilament to Ca(2+), but the detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2576bd688760ccdf0471ca66c46dba2e
https://doi.org/10.1016/j.jmb.2010.06.007
https://doi.org/10.1016/j.jmb.2010.06.007
Publikováno v:
Journal of Biological Chemistry. 284:16432-16441
Cardiac thin filament deactivation is initiated by Ca2+ dissociation from troponin C (cTnC), followed by multiple structural changes of thin filament proteins. These structural transitions are the molecular basis underlying the thin filament regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7901bc8d71a06d062509ec2053eb1d
https://doi.org/10.1074/jbc.m808075200
https://doi.org/10.1074/jbc.m808075200
Publikováno v:
Acta Ecologica Sinica. 26:317-325
The total nitrogen, phosphorus, biomass, pH, dissolved oxygen in and temperatures of three eutrophic waters were investigated in the rapid-growth season of phytoplankton (July-October). Chloromonas rosae was cultivated in water samples from three eut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2903e7d994ba5270fc54abcd984c1494
https://doi.org/10.1016/s1872-2032(06)60007-3
https://doi.org/10.1016/s1872-2032(06)60007-3
Publikováno v:
Journal of Biological Chemistry. 279:44621-44627
We have addressed the functional and structural roles of three domains of the chloroplast Rieske iron-sulfur protein; that is, the flexible hinge that connects the transmembrane helix to the soluble cluster-bearing domain, the N-terminal stromal prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f442f53034b05e8a4fc1a46e96115a
https://doi.org/10.1074/jbc.m406955200
https://doi.org/10.1074/jbc.m406955200
Mutations in cardiac troponin I (cTnI) that cause hypertrophic cardiomyopathy (HCM) have been reported to change the contractility of cardiac myofilaments, but the underlying molecular mechanism remains elusive. In this study, Forster resonance energ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34523358bdb12c745805d43a28a29628
https://europepmc.org/articles/PMC3616153/
https://europepmc.org/articles/PMC3616153/
Autor:
Mohammad Robiul Hossan, Cornelius F. Ivory, Yexin Ouyang, Wen-Ji Dong, Prashanta Dutta, Danny Bottenus
Publikováno v:
Lab on a chip. 11(22)
This paper describes the detection of a cardiac biomarker, cardiac troponin I (cTnI), spiked into depleted human serum using cationic isotachophoresis (ITP) in a 3.9 cm long poly(methyl methacrylate) (PMMA) microfluidic channel. The microfluidic chip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3134fd90a168a49a51ef26d7b7f472b9
https://pubmed.ncbi.nlm.nih.gov/21935555
https://pubmed.ncbi.nlm.nih.gov/21935555