Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Yew Kwang Ong"'
Publikováno v:
Military Medical Research, Vol 7, Iss 1, Pp 1-18 (2020)
Abstract The coronavirus disease (COVID-19) pandemic has led to a global struggle to cope with the sheer numbers of infected persons, many of whom require intensive care support or eventually succumb to the illness. The outbreak is managed by a combi
Externí odkaz:
https://doaj.org/article/42669d87f6ba4d47bb24a03f9703b033
Autor:
Akshamal M. Gamage, Kai Sen Tan, Wharton O. Y. Chan, Zhe Zhang Ryan Lew, Jing Liu, Chee Wah Tan, Deepa Rajagopalan, Quy Xiao Xuan Lin, Le Min Tan, Prasanna Nori Venkatesh, Yew Kwang Ong, Mark Thong, Raymond Tzer Pin Lin, Shyam Prabhakar, De Yun Wang, Lin-Fa Wang
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The dynamics of SARS-CoV-2 infection in COVID-19 patients are highly variable, with a subset of patients demonstrating prolonged virus shedding, which poses a significant challenge for disease management and transmission control. In this stu
Externí odkaz:
https://doaj.org/article/90f0bab02d34444a9ecc6db6b4004829
Autor:
Zhuang Gui Chen, Zhao Ni Wang, Yan Yan, Jing Liu, Ting Ting He, Kim Thye Thong, Yew Kwang Ong, Vincent T. K. Chow, Kai Sen Tan, De Yun Wang
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Cell-surface mucins are expressed in apical epithelial cells of the respiratory tract, and contribute a crucial part of the innate immune system. Despite anti-inflammatory or antiviral functions being revealed for certain cell-sur
Externí odkaz:
https://doaj.org/article/4a2688ce2698416eaf7592268e425539
Host Antiviral Response Suppresses Ciliogenesis and Motile Ciliary Functions in the Nasal Epithelium
Autor:
Qianmin Chen, Kai Sen Tan, Jing Liu, Hsiao Hui Ong, Suizi Zhou, Hongming Huang, Hailing Chen, Yew Kwang Ong, Mark Thong, Vincent T. Chow, Qianhui Qiu, De-Yun Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundRespiratory viral infections are one of the main drivers of development and exacerbation for chronic airway inflammatory diseases. Increased viral susceptibility and impaired mucociliary clearance are often associated with chronic airway in
Externí odkaz:
https://doaj.org/article/30c3af8b4c974e1f9ec3ea10345691e4
Autor:
Akshamal M Gamage, Kai Sen Tan, Wharton O Y Chan, Jing Liu, Chee Wah Tan, Yew Kwang Ong, Mark Thong, Anand K Andiappan, Danielle E Anderson, De Yun Wang, Lin-Fa Wang
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009130 (2020)
The novel coronavirus SARS-CoV-2 is the causative agent of Coronavirus Disease 2019 (COVID-19), a global healthcare and economic catastrophe. Understanding of the host immune response to SARS-CoV-2 is still in its infancy. A 382-nt deletion strain la
Externí odkaz:
https://doaj.org/article/22bd2e51569a4104a446fde97cbfe7b9
Autor:
Yang Peng, Wei-jie Guan, Kai Sen Tan, Zhenchao Zhu, Zhuo Chen, Haiyu Hong, Zhaoni Wang, Tengfei Tian, Xiaoxue Zi, Yew Kwang Ong, Mark Thong, Li Shi, Qintai Yang, Qianhui Qiu, De-Yun Wang
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 14, Iss 1, Pp 1-9 (2018)
Abstract Background Upper airway inflammatory diseases are associated with abnormal expression of nasal epithelial forkhead-box J1 (FOXJ1) which regulates motile cilia formation. We sought to investigate whether aberrant FOXJ1 localizations correlate
Externí odkaz:
https://doaj.org/article/007ab4877e0749d89bf8db4cb23b7e05
Autor:
Kai Sen Tan, Anand Kumar Andiappan, Bernett Lee, Yan Yan, Jing Liu, See Aik Tang, Josephine Lum, Ting Ting He, Yew Kwang Ong, Mark Thong, Hui Fang Lim, Hyung Won Choi, Olaf Rotzschke, Vincent T Chow, De Yun Wang
Publikováno v:
Cells, Vol 8, Iss 9, p 986 (2019)
The human nasal epithelium is the primary site of exposure to influenza virus, the initiator of host responses to influenza and the resultant pathologies. Influenza virus may cause serious respiratory infection resulting in major complications, as we
Externí odkaz:
https://doaj.org/article/6281ea9ac8104afc8eaa166cf5bc8eb2
Autor:
Han Wen Mak, Shan Hui Lee, Jeremy Chee, Ivan Tham, Boon Cher Goh, Siew Shuen Chao, Yew Kwang Ong, Kwok Seng Loh, Chwee Ming Lim
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126108 (2015)
Nasopharyngeal cancer (NPC) is endemic among Chinese populations in Southeast Asia. However, the outcomes of non-Chinese NPC patients in Singapore are not well reported.To determine if non-Chinese NPC patients have a different prognosis and examine t
Externí odkaz:
https://doaj.org/article/0ed150b4f7c54bc88a4c94c98cff8da8
Publikováno v:
Surgical Techniques Development, Vol 2, Iss 1, Pp e5-e5 (2012)
Preservation of olfactory function during anterior skull base surgery has been previously described. However, its feasibility during oncological resection remains undefined. The aim of this study was to clarify the feasibility of preserving olfactory
Externí odkaz:
https://doaj.org/article/96cbee0df07348d0b01d8f24ce0188ea
Autor:
Xinni Xu, Anil Gopinathan, Yew Kwang Ong, Mark Kim Thye Thong, Woei Shyang Loh, Kwok Seng Loh
Publikováno v:
Head & Neck. 45:1604-1614
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::294d3914cc0f83b8f0687a43115f5f08
https://doi.org/10.1002/hed.27367
https://doi.org/10.1002/hed.27367