The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice.

Autor: Monteiro-Cardoso VF; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Translational Laboratories in Genetic Medicine, Agency for Science, Technology and Research, Singapore, Singapore., Yeo XY; Institute for Molecular and Cellular Biology, Agency for Science, Technology and Research, Singapore, Singapore; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Department of Medical Science, College of Medicine, CHA University, Pocheon, Republic of Korea., Bae HG; Institute for Molecular and Cellular Biology, Agency for Science, Technology and Research, Singapore, Singapore; Department of Life Sciences, Yeungnam University, Gyeongsan, South Korea., Mayan DC; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Translational Laboratories in Genetic Medicine, Agency for Science, Technology and Research, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore., Wehbe M; Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Lee S; Institute for Molecular and Cellular Biology, Agency for Science, Technology and Research, Singapore, Singapore., Krishna-K K; Department of Physiology and Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore., Baek SH; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Palomera LF; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Wu LH; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Pakkiri LS; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Shanmugam S; Translational Laboratories in Genetic Medicine, Agency for Science, Technology and Research, Singapore, Singapore., Sem KP; Translational Laboratories in Genetic Medicine, Agency for Science, Technology and Research, Singapore, Singapore., Yew MG; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Parsons MP; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland, Canada., Hayden MR; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada., Yeo LLL; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Division of Neurology, Department of Medicine, National University Hospital, Singapore, Singapore., Sharma VK; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Division of Neurology, Department of Medicine, National University Hospital, Singapore, Singapore., Drum C; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Liehn EA; Institute for Innovation and eHealth, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania; The Heart Center, Singapore, Singapore., Sajikumar S; Department of Physiology and Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore., Davanger S; Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Jo DG; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Chan MYY; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan BYQ; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Division of Neurology, Department of Medicine, National University Hospital, Singapore, Singapore., Jung S; Institute for Molecular and Cellular Biology, Agency for Science, Technology and Research, Singapore, Singapore; Department of Medical Science, College of Medicine, CHA University, Pocheon, Republic of Korea; Department of Physiology and Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore. Electronic address: jungsy0505@cha.ac.kr., Singaraja RR; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Translational Laboratories in Genetic Medicine, Agency for Science, Technology and Research, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore. Electronic address: mdcrrs@nus.edu.sg.

Publikováno v: Journal of lipid research [J Lipid Res] 2024 Nov 21; Vol. 66 (1), pp. 100712. Date of Electronic Publication: 2024 Nov 21.