Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yevgeniya I. Shurubor"'
Autor:
Nneka Southwell, Guido Primiano, Viraj Nadkarni, Nabeel Attarwala, Emelie Beattie, Dawson Miller, Sumaitaah Alam, Irene Liparulo, Yevgeniya I Shurubor, Maria Lucia Valentino, Valerio Carelli, Serenella Servidei, Steven S Gross, Giovanni Manfredi, Qiuying Chen, Marilena D'Aurelio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 7, Pp 1-26 (2023)
Abstract Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy‐dependent, mitochondrial diseases often affect skeletal muscle
Externí odkaz:
https://doaj.org/article/3ac8c9834e7f48439c744d6d9391fd6b
Autor:
Yevgeniya I. Shurubor, Andrey B. Krasnikov, Elena P. Isakova, Yulia I. Deryabina, Vladimir S. Yudin, Anton A. Keskinov, Boris F. Krasnikov
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 217 (2024)
In the example of a rat model with chronic hepatoencephalopathy (HE), changes in the organ morphology of rats affect the balance of metabolites of the tricarboxylic acid (TCA) cycle and metabolites of the glutamine–glutamate (Gln-Glu) cycle, namely
Externí odkaz:
https://doaj.org/article/1e3e80cca50e43f9b1f69c7aec763287
Preparative Biocatalytic Synthesis of α-Ketomethylselenobutyrate—A Putative Agent for Cancer Therapy
Autor:
Maksim V. Nikulin, Viktor V. Drobot, Yevgeniya I. Shurubor, Vytas K. Švedas, Boris F. Krasnikov
Publikováno v:
Molecules, Vol 28, Iss 17, p 6178 (2023)
Biomedical studies of the role of organic selenium compounds indicate that the amino acid derivative of L-selenomethionine, α-ketomethylselenobutyrate (KMSB), can be considered a potential anticancer therapeutic agent. It was noted that, in addition
Externí odkaz:
https://doaj.org/article/9c8ad6a8f6e6492e8a228547fbb476ef
Autor:
Anna L. Kaysheva, Arthur T. Kopylov, Alexander A. Stepanov, Kristina A. Malsagova, Alexander A. Izotov, Yevgeniya I. Shurubor, Boris F. Krasnikov
Publikováno v:
Metabolites, Vol 13, Iss 1, p 16 (2022)
A highly sensitive method for the qualitative and quantitative determination of amino- and carboxylic acids, as well as a number of urea and methionine cycle metabolites in the studied solutions, is presented. Derivatives (esterification) were obtain
Externí odkaz:
https://doaj.org/article/3e2b70c412c440d3805fb77c5c3f3949
Autor:
Tatyana I. Rakhmanova, Varvara Yu. Sekova, Natalya N. Gessler, Elena P. Isakova, Yulia I. Deryabina, Tatyana N. Popova, Yevgeniya I. Shurubor, Boris F. Krasnikov
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7670
This paper presents an analysis of the regulation activity of the partially purified preparations of cellular aconitate hydratase (AH) on the yeast Yarrowia lipolytica cultivated at extreme pH. As a result of purification, enzyme preparations were ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e29cece0ebba09fdde0e1df30e4f55
https://doi.org/10.3390/ijms24087670
https://doi.org/10.3390/ijms24087670
Autor:
Yevgeniya I. Shurubor, Alexander E. Rogozhin, Elena P. Isakova, Yulia I. Deryabina, Boris F. Krasnikov
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3647
Volume 24
Issue 4
Pages: 3647
The delayed consequences of the influence of hepatic encephalopathy (HE) on the metabolism of animals have not been studied enough. We have previously shown that the development of acute HE under the influence of the thioacetamide (TAA) toxin is acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1176ec479786b4157db8506d28dae8
https://doi.org/10.3390/ijms24043647
https://doi.org/10.3390/ijms24043647
Autor:
Yevgeniya I. Shurubor, Alexander E. Rogozhin, Elena P. Isakova, Yulia I. Deryabina, Boris F. Krasnikov
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1384
Exposure to the toxin thioacetamide (TAA) causes acute hepatic encephalopathy (HE), changes in the functioning of systemic organs, and an imbalance in a number of energy metabolites. The deferred effects after acute HE development are poorly understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed551afb8bb36f79a536012555ea595
https://doi.org/10.3390/ijms24021384
https://doi.org/10.3390/ijms24021384
Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection
Autor:
Yevgeniya I. Shurubor, Marilena D’Aurelio, Joanne Clark-Matott, Elena P. Isakova, Yulia I. Deryabina, M. Flint Beal, Arthur J. L. Cooper, Boris F. Krasnikov
Publikováno v:
Molecules, Vol 22, Iss 9, p 1388 (2017)
Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) play essential roles in cell energy metabolism. Dysregulation of the biosynthesis and functioning of both compounds may contribute to various pathological conditions. We describe here a simple and s
Externí odkaz:
https://doaj.org/article/4c7eaf3ef90a4746864aeebced8fb847
Autor:
Yaroslav Ya Tyno, A. B. Shevelev, Anna A. Lebedeva, Boris F. Krasnikov, Ekaterina Epova, Elena S. Bogdanova, Arthur J.L. Cooper, Yulia K. Biryukova, Yevgeniya I. Shurubor
Publikováno v:
Analytical biochemistry. 632
Nit2/ω-amidase catalyzes the hydrolysis of α-ketoglutaramate (KGM, the α-keto acid analogue of glutamine) to α-ketoglutarate and ammonia. The enzyme also catalyzes the amide hydrolysis of monoamides of 4- and 5-C-dicarboxylates, including α-keto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9706d3b755feed3663db261688716aa5
https://pubmed.ncbi.nlm.nih.gov/34391728
https://pubmed.ncbi.nlm.nih.gov/34391728
Autor:
Yulia I. Deryabina, Boris F. Krasnikov, Arthur J.L. Cooper, Yevgeniya I. Shurubor, E. P. Isakova, Andrey B Krasnikov, M. Flint Beal
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8918, p 8918 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences
Volume 21
Issue 23
Small biomolecules, such as coenzyme A (CoA) and acetyl coenzyme A (acetyl-CoA), play vital roles in the regulation of cellular energy metabolism. In this paper, we evaluated the delayed effect of the potent hepatotoxin thioacetamide (TAA) on the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06fdd3187425a4516a96154dd8b42bd
https://doi.org/10.3390/ijms21238918
https://doi.org/10.3390/ijms21238918