Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yevgeniy Yuzefpolskiy"'
Autor:
Samuel D. Klebanoff, Lauren B. Rodda, Chihiro Morishima, Mark H. Wener, Yevgeniy Yuzefpolskiy, Estelle Bettelli, Jane H. Buckner, Cate Speake, Marion Pepper, Daniel J. Campbell
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder that causes debilitating swelling and destruction of the joints. People with RA are treated with drugs that actively suppress one or more parts of their immune system, and these
Externí odkaz:
https://doaj.org/article/13459b7a9d15424893fed20f19913b0c
Autor:
David E Place, David R Williamson, Yevgeniy Yuzefpolskiy, Bhuvana Katkere, Surojit Sarkar, Vandana Kalia, Girish S Kirimanjeswara
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190384 (2017)
Progress towards a safe and effective vaccine for the prevention of tularemia has been hindered by a lack of knowledge regarding the correlates of protective adaptive immunity and a lack of tools to generate this knowledge. CD8+ T cells are essential
Externí odkaz:
https://doaj.org/article/a7458847cf2a4c4b90ebbd711dbeeda2
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162674 (2016)
MicroRNAs constitute a major post-transcriptional mechanism for controlling protein expression, and are emerging as key regulators during T cell development and function. Recent reports of augmented CD8 T cell activation and effector differentiation,
Externí odkaz:
https://doaj.org/article/86a76029019c40ed97ea5e620ef7020d
Autor:
Yevgeniy Yuzefpolskiy, Peter Morawski, Mitch Fahning, Cate Speake, Sandra Lord, Anu Chaudhary, Chihiro Morishima, Mark H. Wener, Mariko Kita, Lucas McCarthy, Jane H. Buckner, Daniel J. Campbell, Estelle Bettelli
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 208(7)
Multiple sclerosis (MS) is a demyelinating inflammatory disease of the CNS treated by diverse disease-modifying therapies that suppress the immune system. Severe acute respiratory syndrome coronavirus 2 mRNA vaccines have been very effective in immun
Autor:
Adithya Vegaraju, Vandana Kalia, Candice D. Church, Yevgeniy Yuzefpolskiy, Paul Nghiem, Florian M. Baumann, Surojit Sarkar, Martin Prlic, Abhishek Jha, Hanxi Xiao, Shashank Jatav, Stanley R. Riddell
Publikováno v:
Sci Transl Med
Inhibitory signaling in dysfunctional CD8 T cells through the programmed cell death 1 (PD-1) axis is well established in chronic viral infections and cancers. PD-1 is also transiently induced to high concentrations during priming of acute infections
Autor:
Ryma Toumi, Yevgeniy Yuzefpolskiy, Adithya Vegaraju, Hanxi Xiao, Kendall A. Smith, Surojit Sarkar, Vandana Kalia
Publikováno v:
Cell Reports. 39:110632
Differential interleukin-2 (IL-2) signaling and production are associated with disparate effector and memory fates. Whether the IL-2 signals perceived by CD8 T cells come from autocrine or paracrine sources, the timing of IL-2 signaling and their dif
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
The Journal of Immunology. 204:221.8-221.8
Differential IL-2 signaling is implicated in memory CD8 T cell fates. Autocrine IL-2 production is a hallmark of polyfunctional, long-lived lymphoid memory cells. Whether the IL-2 signals perceived by CD8 T cells come from autocrine or paracrine sour
Publikováno v:
The Journal of Immunology. 204:246.27-246.27
The general paradigm is that the tumor microenvironment is non-conducive to sustaining productive cytotoxic T cell responses due to suppressive and counter-immunity T cell extrinsic factors. It has been shown that the tumor microenvironment can harbo
Autor:
Girish S. Kirimanjeswara, Surojit Sarkar, Yevgeniy Yuzefpolskiy, David R. Williamson, Kalia, David E. Place, Bhuvana Katkere
Progress towards a safe and effective vaccine for the prevention of tularemia has been hindered by a lack of knowledge regarding the correlates of protective adaptive immunity and a lack of tools to generate this knowledge. CD8+T cells are essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b33d8536a3458ad688610745ec74fbe