Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yevgenia, Tesmenitsky"'
A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
Autor:
Viorel Simion, Haoyang Zhou, Stefan Haemmig, Jacob B. Pierce, Shanelle Mendes, Yevgenia Tesmenitsky, Daniel Pérez-Cremades, James F. Lee, Alex F. Chen, Nicoletta Ronda, Bianca Papotti, Jarrod A. Marto, Mark W. Feinberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Long non coding RNA molecules have been implicated in the immunopathology of a range of inflammatory pathologies. Here the authors show lncRNA MAARS regulates apoptosis via interaction with HuR in the context of atherosclerosis.
Externí odkaz:
https://doaj.org/article/a42036a2b39749688a2059d2a4192cf7
Autor:
Viorel Simion, Haoyang Zhou, Jacob B. Pierce, Dafeng Yang, Stefan Haemmig, Yevgenia Tesmenitsky, Galina Sukhova, Peter H. Stone, Peter Libby, Mark W. Feinberg
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Long noncoding RNAs (lncRNAs) play important roles in regulating diverse cellular processes in the vessel wall, including atherosclerosis. RNA-Seq profiling of intimal lesions revealed a lncRNA, VINAS (Vascular INflammation and Atherosclerosis lncRNA
Externí odkaz:
https://doaj.org/article/f22d8d77a09c4d4099a3cbfb05f31e86
Autor:
Andrew G. Cox, Diane C. Saunders, Peter B. Kelsey Jr., Allie A. Conway, Yevgenia Tesmenitsky, Julio F. Marchini, Kristin K. Brown, Jonathan S. Stamler, Dorothy B. Colagiovanni, Gary J. Rosenthal, Kevin J. Croce, Trista E. North, Wolfram Goessling
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 56-69 (2014)
Toxic liver injury is a leading cause of liver failure and death because of the organ’s inability to regenerate amidst massive cell death, and few therapeutic options exist. The mechanisms coordinating damage protection and repair are poorly unders
Externí odkaz:
https://doaj.org/article/b0dbc49cf4944575a2e417e636885493
Autor:
Grasiele Sausen, Frederik Kloss, Mi Kyung Yu, Gha Young Lee, Roberto Molinaro, Eduardo J. Folco, Jinjun Shi, Omid C. Farokhzad, Peter Libby, Yevgenia Tesmenitsky, Kevin Croce, Claudia Corbo, Galina K. Sukhova, Colette A. Bichsel, Eugenia Shvartz, Yuan Liu
Publikováno v:
Cardiovasc Res
Aims Recent evidence suggests that ‘vulnerable plaques’, which have received intense attention as underlying mechanism of acute coronary syndromes over the decades, actually rarely rupture and cause clinical events. Superficial plaque erosion has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b91fe1dfac79a82f4dbbe34fc73df
http://hdl.handle.net/10281/347768
http://hdl.handle.net/10281/347768
A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
Autor:
Shanelle Mendes, Daniel Pérez-Cremades, Bianca Papotti, Haoyang Zhou, Mark W. Feinberg, Stefan Haemmig, Alex F. Chen, Yevgenia Tesmenitsky, James F. Lee, Nicoletta Ronda, Jarrod A. Marto, Viorel Simion, Jacob B. Pierce
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a macrophage-specific lncRNA MAARS (Macrophage-Associated Atheroscler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39ac98ea74a6d1ad14e21dd1bdf754a
http://europepmc.org/articles/PMC7708640
http://europepmc.org/articles/PMC7708640
Autor:
Shah Kavi, Peter Libby, Tetsushi Nakao, Rob S. Sellar, Paul Carter, M. J. Gomes, Samuel D. Moscavitch, Yevgenia Tesmenitsky, Eugenia Shvartz, Marie McConkey, Victoria Ruvkun, Eva Kritikou, Shamsudheen K. Vellarikkal, Galina K. Sukhova, Waihay J. Wong, Benjamin L. Ebert, Andrew H. Lichtman, Amelie Vromman, Grasiele Sausen, Rajat M. Gupta
Publikováno v:
Circulation. 142
Introduction: Clonal hematopoiesis of indeterminate potential (CHIP) describes somatic mutations of bone marrow derived blood cells in the absence of overt hematological disease. CHIP correlates with aging and atherosclerotic cardiovascular diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b46214f176f5be6774b7593f633384
https://doi.org/10.1161/circ.142.suppl_3.15355
https://doi.org/10.1161/circ.142.suppl_3.15355
Autor:
Eugenia Shvartz, Frederik Kloss, Mi Kyung Yu, Gha Young Lee, Roberto Molinaro, Collette A Bichsel, Peter Libby, Omid C. Farokhzad, Yevgenia Tesmenitsky, Claudia Corbo, Galina K. Sukhova, Kevin Croce, Jinjun Shi
Publikováno v:
Circulation. 142
Introduction: Superficial plaque erosion has emerged as a growing cause of residual thrombotic complications of atherosclerosis in an era of effective lipid lowering, anti-hypertensive therapy, and smoking cessation. The mechanisms of plaque erosion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd5477b797386f4e9235fe2829b208ca
https://doi.org/10.1161/circ.142.suppl_3.15700
https://doi.org/10.1161/circ.142.suppl_3.15700
Autor:
Dafeng Yang, Haoyang Zhou, Viorel Simion, Stefan Haemmig, Yevgenia Tesmenitsky, Mark W. Feinberg, Peter Stone, Peter Libby, Jacob B. Pierce, Galina K. Sukhova
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
JCI Insight
JCI Insight
Long noncoding RNAs (lncRNAs) play important roles in regulating diverse cellular processes in the vessel wall, including atherosclerosis. RNA-Seq profiling of intimal lesions revealed a lncRNA, VINAS (Vascular INflammation and Atherosclerosis lncRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3156cdec99a71eb5877363e7131fb32c
https://doaj.org/article/f22d8d77a09c4d4099a3cbfb05f31e86
https://doaj.org/article/f22d8d77a09c4d4099a3cbfb05f31e86
Autor:
Johan Auwerx, Yevgenia Tesmenitsky, Peter Libby, Warren L. Lee, Jarrod A. Marto, Tianlun Yang, Dafeng Yang, Stefan Haemmig, Yihuan Deng, Daniel Freeman, A.K.M. Khyrul Wara, Viorel Simion, James F. Lee, Mark W. Feinberg, Lei Chen, Siavash Ghaffari, Debapria Das, Xinghui Sun, Eugenia Shvartz, Galina Sukova, Peter Stone, Roberto Molinaro, Norman Moullan
Publikováno v:
Science Translational Medicine. 12
Long noncoding RNAs (lncRNAs) are emerging regulators of biological processes in the vessel wall; however, their role in atherosclerosis remains poorly defined. We used RNA sequencing to profile lncRNAs derived specifically from the aortic intima of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16584239cc39de5c96d698187931faae
https://doi.org/10.1126/scitranslmed.aaw1868
https://doi.org/10.1126/scitranslmed.aaw1868
Autor:
Akm Khyrul, Wara, Shijia, Wang, Chun, Wu, Fang, Fang, Stefan, Haemmig, Brittany N, Weber, Ceren O, Aydogan, Yevgenia, Tesmenitsky, Hassan, Aliakbarian, John R, Hawse, Malayannan, Subramaniam, Lei, Zhao, Peter T, Sage, Ali, Tavakkoli, Amanda, Garza, Lydia, Lynch, Alexander S, Banks, Mark W, Feinberg
Publikováno v:
Cell reports
SUMMARY CD4+ T cells regulate inflammation and metabolism in obesity. An imbalance of CD4+ T regulatory cells (Tregs) is critical in the development of insulin resistance and diabetes. Although cytokine control of this process is well understood, tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b1f6cde659315b2a30c2d8a4f21a4f9
https://pubmed.ncbi.nlm.nih.gov/33378664
https://pubmed.ncbi.nlm.nih.gov/33378664