Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Yeun-Mun Choo"'
Autor:
Dev Karan, Seema Dubey, Sumedha Gunewardena, Kenneth A. Iczkowski, Manohar Singh, Pengyuan Liu, Angelo Poletti, Yeun‐Mun Choo, Hui‐Zi Chen, Mark T. Hamann
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 1966-1979 (2024)
The androgen receptor (AR) is the main driver in the development of castration‐resistant prostate cancer, where the emergence of AR splice variants leads to treatment‐resistant disease. Through detailed molecular studies of the marine alkaloid ma
Externí odkaz:
https://doaj.org/article/8a6bd94c9bdf47e0a2052c8d7ddc3d56
Autor:
Zhiwei Bian, Menny M. Benjamin, Lucas Bialousow, Yintai Tian, G. Aaron Hobbs, Dev Karan, Yeun-Mun Choo, Mark T. Hamann, Xiaojuan Wang
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33204- (2024)
Sine oculis homeoprotein 1 (SIX1), a prominent representative of the homeodomain transcription factors within the SIX family, has attracted significant interest owing to its role in tumorigenesis, cancer progression, and prognostic assessments. Initi
Externí odkaz:
https://doaj.org/article/a201e0c4d5c54445b4f037ceae53416a
Autor:
Min-Yu Lee, Jun-Ping Shiau, Jen-Yang Tang, Ming-Feng Hou, Phoebe Sussana Primus, Chai-Lin Kao, Yeun-Mun Choo, Hsueh-Wei Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7751 (2023)
Triple-negative breast cancer (TNBC) is insensitive to target therapy for non-TNBC and needs novel drug discovery. Extracts of the traditional herb Boesenbergia plant in Southern Asia exhibit anticancer effects and contain novel bioactive compounds b
Externí odkaz:
https://doaj.org/article/73017c79c7604c21a9457bfa9679ac6c
Autor:
Scott Wyer, Danyelle M. Townsend, Zhiwei Ye, Antonis Kourtidis, Yeun-Mun Choo, André Luís Branco de Barros, Mohamed S. Donia, Mark T. Hamann
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112676- (2022)
Since the discovery of the kahalalide family of marine depsipeptides in 1993, considerable work has been done to develop these compounds as new and biologically distinct anti-cancer agents. Clinical trials and laboratory research have yielded a wealt
Externí odkaz:
https://doaj.org/article/e896a4d71c4840339a42753841d51db1
Publikováno v:
Ultrasonics Sonochemistry, Vol 79, Iss , Pp 105793- (2021)
Pandan (Pandanus amaryllifolius) is commonly used as a food ingredient in Southeast Asia due to its delicious flavor, appetizing aroma and bright green colour. Pandan plant is uniquely found only in certain parts of the world. Despite its increasing
Externí odkaz:
https://doaj.org/article/787e407e67394c9e96d6ec1362af77c0
Publikováno v:
Applied Sciences, Vol 12, Iss 21, p 11007 (2022)
In this study, the extraction efficiency of β-asarone from Malaysian Acorus calamus from Acoraceae family using conventional solvent extraction and ultrasound-assisted extraction techniques was compared. The results showed that the ultrasound-assist
Externí odkaz:
https://doaj.org/article/41a194b228354b45bec1ebf0af6484cf
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 647 (2022)
Manzamine-A is a marine-derived alkaloid which has anti-viral and anti-proliferative properties and is currently being investigated for its efficacy in the treatment of certain viruses (malaria, herpes, HIV-1) and cancers (breast, cervical, colorecta
Externí odkaz:
https://doaj.org/article/70a763f1613844898a53892b5697b1f0
Publikováno v:
Natural Product Research. :1-8
Two new bisanthraquinones, glabraquinone A and B (1–2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3e9e01d2ea079c33905b8d4bd325bb
https://doi.org/10.1080/14786419.2022.2147932
https://doi.org/10.1080/14786419.2022.2147932
Autor:
Alejandro M. S. Mayer, Mary L. Hall, Joseph Lach, Jonathan Clifford, Kevin Chandrasena, Caitlin Canton, Maria Kontoyianni, Yeun-Mun Choo, Dev Karan, Mark T. Hamann
Publikováno v:
Marine Drugs, Vol 19, Iss 9, p 506 (2021)
Manzamines are complex polycyclic marine-derived β-carboline alkaloids with reported anticancer, immunostimulatory, anti-inflammatory, antibacterial, antiviral, antimalarial, neuritogenic, hyperlipidemia, and atherosclerosis suppression bioactivitie
Externí odkaz:
https://doaj.org/article/b3bab1dd54084d17be970cacbdcf5f09
Autor:
Devadoss J. Samuvel, Nga T. Nguyen, Hartmut Jaeschke, John J. Lemasters, Xiaojuan Wang, Yeun-Mun Choo, Mark T. Hamann, Zhi Zhong
Publikováno v:
J Nat Prod
Oxidative stress plays an important role in acetaminophen (APAP) -induced hepatotoxicity. Platanosides (PTSs) isolated from the American sycamore tree (Platanus occidentalis) represent a potential new 4-molecule botanical-drug class of antibiotics ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1023811407229365813947c9df7a750
https://doi.org/10.1021/acs.jnatprod.2c00324
https://doi.org/10.1021/acs.jnatprod.2c00324