Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yeun-Jin Ju"'
Autor:
Kee-Ho Lee, Sang Hoon Kim, Gil Hong Park, Gyesoon Yoon, Myung-Haing Cho, Su-Jae Lee, Hee-Yong Chung, Su Hwa Jang, Chang-Mo Kang, Yeun-Jin Ju, Bu-Yeo Kim, Hee Young Kim, Sun Hee Yoon, Young-Hoon Han, Miyong Yun
Supplementary Figures S1-S7 from p31comet Induces Cellular Senescence through p21 Accumulation and Mad2 Disruption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf36381f2ec905b8925d8f56a5cfdbd4
https://doi.org/10.1158/1541-7786.22519495
https://doi.org/10.1158/1541-7786.22519495
Autor:
Yang Hyun Kim, Kee Ho Lee, Gil Hong Park, Sung Hee Hong, Jeong Eun Park, Yeun Jin Ju, Eun Ran Park, Seon Rang Woo, Hyun Joo, Hyun-Jin Shin
Publikováno v:
Journal of Microbiology and Biotechnology. 23:1785-1790
The synthetic machinery of ATF4 (activating transcription factor 4) is activated in response to various stress conditions involved in nutrient restriction, endoplasmic reticulum homeostasis, and oxidation. Stress-induced inhibition of proteasome acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd9eaac4c250510d6ba669513cb8d17
https://doi.org/10.4014/jmb.1309.09027
https://doi.org/10.4014/jmb.1309.09027
Autor:
Yeun Jin Ju, Kee Ho Lee, Hyun Jin Shin, Miyong Yun, Jeong Eun Park, Joon Kim, Myung-Haing Cho, Hyun Yoo Joo, Su-Hyeon Kim, Eun Ran Park, Yan Nan Shen, Seon Rang Woo, Sung Hee Hong, Sang-Gu Hwang
Publikováno v:
Biochemical and Biophysical Research Communications. 424:681-686
Upon apoptotic stimulation, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a cytosolic enzyme normally active in glycolysis, translocates into the nucleus and activates an apoptotic cascade therein. In the present work, we show that SIRT1 prevents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d459957527340e085361adce11a17ced
https://doi.org/10.1016/j.bbrc.2012.07.006
https://doi.org/10.1016/j.bbrc.2012.07.006
Autor:
Sang Hoon Kim, Gil Hong Park, Chang Mo Kang, Hee Young Kim, Gyesoon Yoon, Kee-Ho Lee, Myung-Haing Cho, Yeun-Jin Ju, Hee-Yong Chung, Sun Hee Yoon, Miyong Yun, Young-Hoon Han, Su Hwa Jang, Bu-Yeo Kim, Su Jae Lee
Publikováno v:
Molecular Cancer Research. 7:371-382
Functional suppression of spindle checkpoint protein activity results in apoptotic cell death arising from mitotic failure, including defective spindle formation, chromosome missegregation, and premature mitotic exit. The recently identified p31comet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502d0b95419d1e8e044cbfe4af3c3345
https://doi.org/10.1158/1541-7786.mcr-08-0056
https://doi.org/10.1158/1541-7786.mcr-08-0056
Autor:
Yong-Su Yi, Hyun Mi Choi, Jeong Eun Park, Kyung Mi Lee, Kee-Ho Lee, Ham Yong-Ho, Yeun-Jin Ju, Miyong Yun, Juneyoung Lee, Gil-Hong Park, Tae Jin Kim, Gwi Jung Han, Jong Hoon Lee, Jong Seol Han
Publikováno v:
Experimental & Molecular Medicine. 38:686-693
The gradual loss of telomeric DNA can contribute to replicative senescence and thus, having longer telomeric DNA is generally considered to provide a longer lifespan. Maintenance and stabilization of telomeric DNA is assisted by binding of multiple D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd30fe7cfdfa868a31ee79ba318cea1
https://doi.org/10.1038/emm.2006.81
https://doi.org/10.1038/emm.2006.81
Autor:
Lynda Chin, Linda A. Cannizzaro, K. Lenhard Rudolph, Yeun Jin Ju, Ronald A. DePinho, Sarah R. Weiler, Roger A. Greenberg, Kee Ho Lee
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3381-3386
Telomerase inhibition has been touted as a novel cancer-selective therapeutic goal based on the observation of high telomerase levels in most cancers and the importance of telomere maintenance in long-term cellular growth and survival. Here, the impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769b4287addff48cb8de392779baf0c0
https://doi.org/10.1073/pnas.051629198
https://doi.org/10.1073/pnas.051629198
Autor:
Sang-Gu Hwang, Hyun Yoo Joo, Haekwon Kim, Sang Hoon Kim, Miyong Yun, Eun Ran Park, Seon Rang Woo, Sung Hee Hong, Yeun Jin Ju, In Chul Park, Kee Ho Lee, Gil Hong Park, Myung-Haing Cho, Kyoung Mi Juhn, Hyun Jin Shin, Jeong Eun Park, Chang Mo Kang, Hyun Jin Yun, Jae Min Jeong
Publikováno v:
Biochemical and biophysical research communications. 417(1)
Highlights: Black-Right-Pointing-Pointer Under conditions of telomere erosion, cells become extremely sensitive to H{sub 2}O{sub 2}. Black-Right-Pointing-Pointer Chromosomal regions adjacent to telomeres are cleaved by H{sub 2}O{sub 2} under such con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5293f9d331ec2ef5f1b1cb2a77bd145e
https://pubmed.ncbi.nlm.nih.gov/22138403
https://pubmed.ncbi.nlm.nih.gov/22138403
Autor:
Jung-Kee Lee, Seon Rang Woo, Myung-Haing Cho, Gil Hong Park, Yeun Jin Ju, Sung Hee Hong, In Chul Park, Kee Ho Lee, Kyoung Mi Juhn, Hyun Yoo Joo, Jeong Eun Park, Sang-Gu Hwang, Hyun Jin Shin, Chang Mo Kang, Hae Kwon Kim, Eun Ran Park
Publikováno v:
Biochemical and biophysical research communications. 404(2)
The anticancer effect of paclitaxel is attributable principally to irreversible promotion of microtubule stabilization and is hampered upon development of chemoresistance by tumor cells. Telomere shortening, and eventual telomere erosion, evoke chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3497ff1421e762b2906192c49be450d2
https://pubmed.ncbi.nlm.nih.gov/21144828
https://pubmed.ncbi.nlm.nih.gov/21144828
Autor:
Gil Hong Park, Young Hoon Han, Jeong Eun Park, Hyun-Chul Kim, Won Bong Park, Kyoung Mi Juhn, Seon Rang Woo, Chang Mo Kang, Young Do Yoo, Hyun Jin Shin, Myung-Haing Cho, Sung Hee Hong, Sang-Gu Hwang, Yeun Jin Ju, Kee Ho Lee
Publikováno v:
Biochemical and biophysical research communications. 402(2)
A combination of a radiotherapeutic regimen with telomerase inhibition is valuable when tumor cells are to be sensitized to radiation. Here, we describe cell clones unresponsive to radiosensitization after telomere shortening. After extensive divisio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8593ae7e8bf3b036d809b14a14ee10a
https://pubmed.ncbi.nlm.nih.gov/20875790
https://pubmed.ncbi.nlm.nih.gov/20875790
Autor:
Miyong Yun, Yeun Jin Ju, Jeong Eun Park, Won Bong Park, Kee Ho Lee, Myung Haeng Cho, Myung Jin Park, Kwok-Kin Wong, Kyoung Mi Juhn, Gil Hong Park, Jae Min Jeong, Kang Yell Choi
Publikováno v:
International Journal of Oncology.
Loss of p53 tumor suppressor facilitates acquisition of telomerase activity. In fact, both p53 inactivation and telomerase activation are frequently found in human cancers. p53 inactivation, however, eliminates or attenuates the biological responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95169a1af47c9d68079f1fd5f592aedb
https://doi.org/10.3892/ijo.29.4.753
https://doi.org/10.3892/ijo.29.4.753