Effects of Steady Low-Intensity Exercise on High-Fat Diet Stimulated Breast Cancer Progression Via the Alteration of Macrophage Polarization

Autor: Min Kyoon Kim MD, PhD, Yesl Kim MS, SeungHwa Park MS, Eunju Kim PhD, Yerin Kim MS, Yuri Kim PhD, Jung-Hyun Kim PhD

Publikováno v: Integrative Cancer Therapies, Vol 19 (2020)

Physical inactivity and high-fat diet, especially high saturated fat containing diet are established risk factors for breast cancer that are amenable to intervention. High-fat diet has been shown to induce tumor growth and metastasis by alteration of

Externí odkaz: https://doaj.org/article/0fe63e50324e42f1bba98bffecbd37dc

Blood Transcriptomes of SARS-CoV-2–Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to Severity

Autor: Zeguo Sun, Zhongyang Zhang, Khadija Banu, Yorg Al Azzi, Anand Reghuvaran, Samuel Fredericks, Marina Planoutene, Susan Hartzell, Yesl Kim, John Pell, Gregory Tietjen, William Asch, Sanjay Kulkarni, Richard Formica, Meenakshi Rana, Jonathan S. Maltzman, Weijia Zhang, Enver Akalin, Peter S. Heeger, Paolo Cravedi, Madhav C. Menon

Publikováno v: medRxiv

BACKGROUND: Kidney transplant recipients (KTRs) with COVID-19 have poor outcomes compared to non-KTRs. To provide insight into management of immunosuppression during acute illness, we studied immune signatures from the peripheral blood during and aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be46dcb02e545af4bc874d8881e1f99b
https://doi.org/10.1681/asn.2022010125

Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation

Autor: Patrick Zhang, Gongyong Peng, Aiqin Cao, Yesl Kim, Shravani Pasupneti, Michael Snyder, Hassan Chaib, Ting Hsuan Wu, Yon K. Sung, Marlene Rabinovitch, Wen Tian, Norbert F. Voelkel, Allen B. Tu, Xinguo Jiang, Peter Maguire, Petra Dahms, Lingli Wang, Mark R. Nicolls, Marc Peters-Golden, Peter N. Kao, Marc Humbert, Peter Dorfmüller, Eric M. Shuffle, Roham T. Zamanian, James Chappell

Publikováno v: Tian, W, Jiang, X, Sung, Y K, Shuffle, E, Wu, T H, Kao, P N, Tu, A B, Dorfmüller, P, Cao, A, Wang, L, Peng, G, Kim, Y, Zhang, P, Chappell, J, Pasupneti, S, Dahms, P, Maguire, P, Chaib, H, Zamanian, R, Peters-Golden, M, Snyder, M P, Voelkel, N F, Humbert, M, Rabinovitch, M & Nicolls, M R 2019, ' Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation ', Circulation, vol. 140, no. 17, pp. 1409-1425 . https://doi.org/10.1161/CIRCULATIONAHA.119.040629
Circulation, 140(17), 1409-1425. Lippincott Williams and Wilkins
Circulation

Background: Bmpr2 (bone morphogenetic protein receptor 2) mutations are critical risk factors for hereditary pulmonary arterial hypertension (PAH) with approximately 20% of carriers developing disease. There is an unmet medical need to understand how

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a558c2d58d84632a97d1facafc6e68f1
https://research.vumc.nl/en/publications/83bc2207-15ad-48bd-9cf4-41ce521da2eb

Unripe Rubus coreanus Miquel suppresses migration and invasion of human prostate cancer cells by reducing matrix metalloproteinase expression

Autor: Yesl Kim, Seung Min Lee, Jung-Hyun Kim

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 78:1402-1411

Rubus coreanus Miquel (RCM) is used to promote prostate health and has been shown to have anti-oxidant and anti-carcinogenic activities. However, the effects and mechanisms of RCM on prostate cancer metastasis remain unclear. PC-3 and DU 145 cells we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80ede865c9d1cd1fab8775bccbe96fe
https://doi.org/10.1080/09168451.2014.921550

Rubus coreanus Miquel inhibits prostate cancer invasion and migration by reduction of MMP‐2 and MMP‐9 expression

Autor: Jung-Hyun Kim, Yesl Kim, Eunkyo Park

Publikováno v: The FASEB Journal. 26

The growing incidence of prostate cancer and the traditional use of Rubus coreanus Miquel (RCM) for prostate health led us to compare RCM extracts and to test their efficacy in inhibiting the metas...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8aac11f1fe94c4081862123ca4a0f148
https://doi.org/10.1096/fasebj.26.1_supplement.lb439