Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Yesim Gökmen-Polar"'
Autor:
Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-21 (2022)
Abstract The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity. However, imm
Externí odkaz:
https://doaj.org/article/9e5070068683451ebbd1a83b5eb66b7b
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Nonsurgical management of ductal carcinoma in situ is controversial and little is known about the long-term consequences of this approach. In this study, we aimed to determine the risk of (a) upstaging to invasive carcinoma at excision and (
Externí odkaz:
https://doaj.org/article/e20faec312f94160a9470204af5f2ec5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Studies have shown that the presence of tumor infiltrating lymphocytes (TILs) in Triple Negative Breast Cancer (TNBC) is associated with better prognosis. However, the molecular mechanisms underlying these immune cell differences are not wel
Externí odkaz:
https://doaj.org/article/d7464211fb4844b0b58056045ba5e363
Autor:
Yesim Gökmen-Polar, Jason D True, Edyta Vieth, Yuan Gu, Xiaoping Gu, Guihong D Qi, Amber L Mosley, Sunil S Badve
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204658 (2018)
Deleted in Liver Cancer-1 (DLC1), a member of the RhoGAP family of proteins, functions as a tumor suppressor in several cancers including breast cancer. However, its clinical relevance is unclear in breast cancer. In this study, expression of DLC1 wa
Externí odkaz:
https://doaj.org/article/cd563584e9fc4422a41fbd701a8a070e
Autor:
Yesim Gökmen-Polar, Robert W Cook, Chirayu Pankaj Goswami, Jeff Wilkinson, Derek Maetzold, John F Stone, Kristen M Oelschlager, Ioan Tudor Vladislav, Kristen L Shirar, Kenneth A Kesler, Patrick J Loehrer, Sunil Badve
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66047 (2013)
PurposeThymoma represents one of the rarest of all malignancies. Stage and completeness of resection have been used to ascertain postoperative therapeutic strategies albeit with limited prognostic accuracy. A molecular classifier would be useful to i
Externí odkaz:
https://doaj.org/article/41ed131d687c4a1aafa55ebc697a9d0a
Autor:
Sunil Badve, Chirayu Goswami, Yesim Gökmen-Polar, Robert P Nelson, John Henley, Nick Miller, Narjis A Zaheer, George W Sledge, Lang Li, Kenneth A Kesler, Patrick J Loehrer
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42669 (2012)
Histologic classification of thymomas has significant limitations with respect to both subtype definitions and consistency. In order to better understand the biology of the disease processes, we performed whole genome gene expression analysis. RNA wa
Externí odkaz:
https://doaj.org/article/fdb2b57e22cc4b80b1de2f0db9b9d5d6
Autor:
Sunil S, Badve, Yesim, Gökmen-Polar
Publikováno v:
American Society of Clinical Oncology Educational Book. :73-81
The increasing use of neoadjuvant therapy has resulted in therapeutic decisions being made on the basis of diagnostic needle core biopsy. For many patients, this method might yield the only fragment of tumor available for biomarker analysis, necessit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf69e8bb1aaeb69fb4405d0eb26f9449
https://doi.org/10.1200/edbk_351207
https://doi.org/10.1200/edbk_351207
Autor:
Nancy Klauber-DeMore, Cam Patterson, Michael J. Dial, Christoph H. Borchers, David Ketelsen, Harikrishna Nakshatri, Cheng Fan, George W. Sledge, Yesim Gökmen-Polar, Rajendra Bhati
2-Methoxyestradiol (2ME2), an estradiol metabolite with antiproliferative and antiangiogenic activities, is in phase I/II clinical trials for breast cancer. 2ME2 inhibits microtubule polymerization and causes cells to arrest in G2-M. The purpose of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069d3c98cedec764cb6ed5819d4106b4
https://doi.org/10.1158/0008-5472.c.6495242
https://doi.org/10.1158/0008-5472.c.6495242
Autor:
Nancy Klauber-DeMore, Cam Patterson, Michael J. Dial, Christoph H. Borchers, David Ketelsen, Harikrishna Nakshatri, Cheng Fan, George W. Sledge, Yesim Gökmen-Polar, Rajendra Bhati
Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc7a284062982b2ddafdf1234d80bff
https://doi.org/10.1158/0008-5472.22366664
https://doi.org/10.1158/0008-5472.22366664
Autor:
Nancy Klauber-DeMore, Cam Patterson, Michael J. Dial, Christoph H. Borchers, David Ketelsen, Harikrishna Nakshatri, Cheng Fan, George W. Sledge, Yesim Gökmen-Polar, Rajendra Bhati
Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322731aa7dc7e5327fe30b36d57838e2
https://doi.org/10.1158/0008-5472.22366661
https://doi.org/10.1158/0008-5472.22366661