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pro vyhledávání: '"Yeshwanth Mahesh"'
Autor:
Shreya Sharma, Harsha Rani, Yeshwanth Mahesh, Mohit Kumar Jolly, Jagannath Dixit, Vijayalakshmi Mahadevan
Publikováno v:
Translational Oncology, Vol 43, Iss , Pp 101848- (2024)
Epithelial to Mesenchymal transition (EMT) drives cancer metastasis and is governed by genetic and epigenetic alterations at multiple levels of regulation. It is well established that loss/mutation of p53 confers oncogenic function to cancer cells an
Externí odkaz:
https://doaj.org/article/898d5d91d55147e98f5707a79da5070f
Autor:
Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Prakruthi Manjunatha, Shaurya Goyal, Vignesh A Kasiviswanathan, Yeshwanth Mahesh, Soundharya Ramu, Isabelle McMullen, Jason A. Somarelli, Mohit Kumar Jolly
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-16 (2023)
Abstract Background Epithelial-mesenchymal plasticity (EMP) involves bidirectional transitions between epithelial, mesenchymal and multiple intermediary hybrid epithelial/mesenchymal phenotypes. While the process of epithelial-mesenchymal transition
Externí odkaz:
https://doaj.org/article/4fb827dce11f464388ebd3aef912b8ec
The zymogen protease Plasminogen (Plg) and its active form plasmin (Plm) carry out important functions in the blood clot disintegration (breakdown of fibrin fibers) process. Inhibition of plasmin effectively reduces fibrinolysis to circumvent heavy b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4007634f22c8e53dfbbdda487873c427
Autor:
Srinivasulu Cheemanapalli, Chandrasekaran Palaniappan, Yeshwanth Mahesh, Yuvaraj Iyyappan, Suresh Yarrappagaari, Sekar Kanagaraj
Publikováno v:
Computers in Biology and Medicine. 152:106349
Syringic acid (SA) is an active carcinogenesis inhibitor; however, the low bioavailability and unstable functional groups hinder its activity. Here, a chemically synthesized novel SA analog (SA10) is evaluated for its anticancer activity using in-vit